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Thalidomide-O-PEG3-amine HCl

Product Name
Thalidomide-O-PEG3-amine HCl
CAS No.
2387510-82-7
Chemical Name
Thalidomide-O-PEG3-amine HCl
Synonyms
Thalidomide-PEG4-NH2 HCl;4-(H2N-PEG4)-Thalidomide HCl;Thalidomide-O-PEG3-amine HCl;Thalidomide-PEG4-NH2, HCl salt;Thalidomide 4'-ether-PEG3-amine;Thalidomide-PEG4-NH2 (hydrochloride);Thalidomide-O-PEG3-amine hydrochloride;4-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethoxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride;1H-Isoindole-1,3(2H)-dione, 4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)
CBNumber
CB29023930
Formula Weight
485.92
MOL File
2387510-82-7.mol
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Thalidomide-O-PEG3-amine HCl Property

form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

aablocks
Product number
AA01LQ01
Product name
Thalidomide-PEG4-NH2 (hydrochloride)
Purity
≥95%(HPLC)
Packaging
5mg
Price
$89
Updated
2026/05/21
aablocks
Product number
AA01LQ01
Product name
Thalidomide-PEG4-NH2 (hydrochloride)
Purity
≥95%(HPLC)
Packaging
10mg
Price
$142
Updated
2026/05/21
aablocks
Product number
AA01LQ01
Product name
Thalidomide-PEG4-NH2 (hydrochloride)
Purity
≥95%(HPLC)
Packaging
25mg
Price
$318
Updated
2026/05/21
aablocks
Product number
AA01LQ01
Product name
Thalidomide-PEG4-NH2 (hydrochloride)
Purity
≥95%(HPLC)
Packaging
50mg
Price
$508
Updated
2026/05/21
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Thalidomide-O-PEG3-amine HCl Chemical Properties,Usage,Production

Uses

Thalidomide-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

Biological Activity

Thalidomide 4'-ether-PEG3-amine is a functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a short PEG linker ready for conjugation to a target protein ligand. This product has been recently renamed. The previous name for this product was Thalidomide - linker 11

IC 50

Cereblon

storage

Store at -20°C

References

[1] Fischer ES, et al. Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature. 2014 Aug 7;512(7512):49-53.[Content Brief] DOI:10.1038/nature13527

Thalidomide-O-PEG3-amine HCl Preparation Products And Raw materials

Raw materials

Preparation Products

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Thalidomide-O-PEG3-amine HCl Suppliers

Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
89686
Advantage
60
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 19372819560
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9621
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
Jilin Province Woda Biotechnology Co., Ltd.
Tel
13504435624
Email
1927928688@qq.com
Country
China
ProdList
1639
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310 15002144251
Email
marketing@tsbiochem.com
Country
China
ProdList
24956
Advantage
58
Xianning Shen Lan Biomedical Research and Development Co., Ltd.
Tel
18171815831
Email
1341138380@qq.com
Country
China
ProdList
4509
Advantage
58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
6206333 13167063860
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
49998
Advantage
58
Jilin Chinese Academy of Sciences-yanshen Technology
Tel
18143011203
Email
ET-market@chemextension.com
Country
China
ProdList
36825
Advantage
58
Nantong Hanfang Biotechnology Co. , Ltd.
Tel
hanfangpharma@126.com; 18616537568
Email
hanfangpharma@126.com
Country
China
ProdList
25801
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Email
sales1@amateksci.com
Country
China
ProdList
8528
Advantage
58
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View Lastest Price from Thalidomide-O-PEG3-amine HCl manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Thalidomide-O-PEG3-amine hydrochloride 2387510-82-7
Price
US $0.00/mg
Min. Order
100mg
Purity
>99.00%
Supply Ability
100mg
Release date
2024-04-01

2387510-82-7, Thalidomide-O-PEG3-amine HClRelated Search:


  • Thalidomide-O-PEG3-amine HCl
  • Thalidomide-PEG4-NH2 (hydrochloride)
  • Thalidomide-O-PEG3-amine hydrochloride
  • 4-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethoxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
  • Thalidomide-PEG4-NH2, HCl salt
  • 1H-Isoindole-1,3(2H)-dione, 4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)
  • Thalidomide 4'-ether-PEG3-amine
  • 4-(H2N-PEG4)-Thalidomide HCl
  • Thalidomide-PEG4-NH2 HCl
  • 2387510-82-7