4-cyclohexyl-alpha-methylnaphthalene-1-acetic acid

Product Name: 4-cyclohexyl-alpha-methylnaphthalene-1-acetic acid
CAS No.: 71109-09-6
Chemical Name: 4-cyclohexyl-alpha-methylnaphthalene-1-acetic acid
Synonyms: PM-150;Quadrisol;CERM 10202;Vedaprofen CRS;Vedaprofen Standard;4-Cyclohexyl-α-Methyl-;Vedaprofen, 10 mM in DMSO;2-(4-Cyclohexil-1-naphthyl)-propionic Acid;2-(1-cyclohexylnaphthalen-4-yl)propanoic acid;2-(4-Cyclohexylnaphthalen-1-yl)propanoic acid
CBNumber: CB2916590
Molecular Formula: C19H22O2
Formula Weight: 282.38
MOL File: 71109-09-6.mol

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4-cyclohexyl-alpha-methylnaphthalene-1-acetic acid Property

Melting point:: 150°C
Boiling point:: 465.9±14.0 °C(Predicted)
Density: 1.132±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: DMF: 25 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml
form: Solid
pka: 4.90±0.30(Predicted)
color: White to off-white
BRN: 5568831
EPA Substance Registry System: 1-Naphthaleneacetic acid, 4-cyclohexyl-.alpha.-methyl- (71109-09-6)

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Safety

WGK Germany: 3
Toxicity: LD50 orally in rat: 400 mg/kg (Godfroid)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0001093
Product name: Vedaprofen
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0001093
Price: $150
Updated: 2024/03/01

Sigma-Aldrich

Product number: 32533
Product name: Vedaprofen
Purity: VETRANAL
Packaging: 10mg
Price: $254
Updated: 2024/03/01

Cayman Chemical

Product number: 15960
Product name: Vedaprofen
Purity: ≥95%
Packaging: 500μg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 15960
Product name: Vedaprofen
Purity: ≥95%
Packaging: 1mg
Price: $110
Updated: 2024/03/01

Cayman Chemical

Product number: 15960
Product name: Vedaprofen
Purity: ≥95%
Packaging: 5mg
Price: $144
Updated: 2024/03/01

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4-cyclohexyl-alpha-methylnaphthalene-1-acetic acid Chemical Properties,Usage,Production

Chemical Properties

Crystalline Solid

Uses

Propionic acid type non-steroidal anti-inflammatory drug (NSAID).

Definition

ChEBI: A racemate composed of equal amounts of (R)- and (S)-vedaprofen. Used for control of pain and inflammation particularly associated with chronic musculoskeletal disorders and soft tissue trauma in dogs and horses and for tr atment of pain due to horse colic.

Biological Activity

Vedaprofen is a non-steroidal anti-inflammatory drug (NSAID) th at has been found to have antimicrobial activity. Vedaprofen is primarily used as a veterinary analgesic and anti-inflammatory for arthritis and pain. Its anti-inflammatory activity is due to cyclooxygenase inihbition, while its antimicrobial activity is less certain. Vedaprofen can kill B. subtilis by permeabilizing its membrane. Other studies have shown vedaprofen can target the Escherichia coli DNA polymerase III β subunit.

4-cyclohexyl-alpha-methylnaphthalene-1-acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-cyclohexyl-alpha-methylnaphthalene-1-acetic acid Suppliers

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71109-09-6, 4-cyclohexyl-alpha-methylnaphthalene-1-acetic acidRelated Search:

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4-cyclohexyl-alpha-methylnaphthalene-1-acetic acid

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4-Cyclohexyl-a-methyl-1-naphthaleneacetic Acid

CERM 10202

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2-(1-cyclohexylnaphthalen-4-yl)propanoic acid

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Vedaprofen,Inhibitor,nonsteroidal,PM150,PM-150,Escherichia coli,inhibit,CERM-10202,CERM10202,COX,serum TxB2,sliding clamp,anti-inflammatory drug,E. coli,PM 150,COX-1 selective,exudate PGE2,Cyclooxygenase,NSAID

2-(4-Cyclohexylnaphthalen-1-yl)propanoic acid

Vedaprofen, 10 mM in DMSO

71109-09-6

Aromatics

Intermediates & Fine Chemicals

Pharmaceuticals