Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-
- Product Name
- Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-
- CAS No.
- 70209-81-3
- Chemical Name
- Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-
- Synonyms
- Component B1b;Ivermectin B1b;IvermectinH2B1b;avermectin H2B1b;Dihydroavermectin B1b;22,23-Dihydroavermectin B1b;22,23- dihydroavermectin B1b (Ivermectin B1b);22,23-Dihydro-34-nor-5-O-demethylavermectin A1a;DihydroaverMectin B1b, 22,23-DihydroaverMectin B1b;22,23-Dihydro-5-O-demethyl-25-de(1-methylpropyl)-25-isopropylavermectin A1a
- CBNumber
- CB2918291
- Molecular Formula
- C47H72O14
- Formula Weight
- 861.07
- MOL File
- 70209-81-3.mol
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- Property
- Boiling point:
- 934.1±65.0 °C(Predicted)
- Density
- 1.24±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- form
- A solid
- pka
- 12.42±0.70(Predicted)
- Stability:
- Temperature sensitive
Safety
- RIDADR
- 2588
- HazardClass
- 6.1(a)
- PackingGroup
- II
N-Bromosuccinimide Price
- Product number
- 23824
- Product name
- Ivermectin B1b
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $311
- Updated
- 2024/03/01
- Product number
- 23824
- Product name
- Ivermectin B1b
- Purity
- ≥95%
- Packaging
- 2.5mg
- Price
- $1316
- Updated
- 2024/03/01
- Product number
- I940825
- Product name
- IvermectinB1b
- Packaging
- 2.5mg
- Price
- $1220
- Updated
- 2021/12/16
- Product number
- D3570-04A
- Product name
- Ivermectin B1b
- Packaging
- 500ug
- Price
- $478
- Updated
- 2021/12/16
- Product number
- API0017173
- Product name
- B1-BETA-IVERMECTIN COMPONENT
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.15
- Updated
- 2021/12/16
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- Chemical Properties,Usage,Production
Uses
Ivermectin B1b is a minor component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19.
Uses
Ivermectin B1b (dihydroavermectin B1b) is the minor component (<20%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectin/milbemycins are also potent insecticides. In vitro, the B1b (25-iso-propyl) analogue is slightly more potent than the 25-sec-butyl (B1a) analogue as an inhibitor of nematode larval development and paralysis, and also a more sensitive probe for ivermectin resistance.
Definition
ChEBI: A macrocyclic lactone that is avermectin B1b in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the minor component of ivermectin.
brand name
Stromectol (Merck).
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- Preparation Products And Raw materials
Raw materials
Preparation Products
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- Suppliers
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View Lastest Price from Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- manufacturers
- Product
- Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- 70209-81-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%-99.9%
- Supply Ability
- 100kg
- Release date
- 2020-01-10