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5-nitro-2-(4-nitrophenyl)-1H-benzimidazole

Product Name
5-nitro-2-(4-nitrophenyl)-1H-benzimidazole
CAS No.
1772-39-0
Chemical Name
5-nitro-2-(4-nitrophenyl)-1H-benzimidazole
Synonyms
MMP2-IN-2;5-nitro-2-(4-nitrophenyl)-1H-benzimidazole;5-Nitro-2-(4-nitrophenyl)-1H-benzoimidazole;5-Nitro-2-(4-nitrophenyl)benziMidazole, 95%;1H-Benzimidazole, 6-nitro-2-(4-nitrophenyl)-;6-Nitro-2-(4-nitrophenyl)-1H-benzo[d]imidazole
CBNumber
CB2923941
Molecular Formula
C13H8N4O4
Formula Weight
284.23
MOL File
1772-39-0.mol
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5-nitro-2-(4-nitrophenyl)-1H-benzimidazole Property

Melting point:
300 °C
Boiling point:
565.2±56.0 °C(Predicted)
Density 
1.544±0.06 g/cm3(Predicted)
form 
Solid
pka
9.07±0.10(Predicted)
color 
Light brown to brown
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0151110
Product name
5-NITRO-2-(4-NITROPHENYL)-1H-BENZOIMIDAZOLE
Purity
95.00%
Packaging
5MG
Price
$500.27
Updated
2021/12/16
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5-nitro-2-(4-nitrophenyl)-1H-benzimidazole Chemical Properties,Usage,Production

Description

NSC-657186 is a novel selective non-zinc-binding MMP-2 inhibitor.

Uses

MMP2-IN-2 (compound 42) is a potent and selective MMP-2 (matrix metalloproteinases) inhibitor, with an IC50 of 4.2 μM. MMP2-IN-2 also shows inhibitory activity against MMP-13, MMP-9 and MMP-8, with IC50 values of 12, 23.3, and 25 μM, respectively[1].

IC 50

MMP-2: 4.2 ± 0.2 μM (IC50); MMP13: 12 ± 7 μM (IC50); MMP-9: 23.3 ± 10. μM (IC50); MMP-8: 25 ± 10 μM (IC50)

References

[1] Laghezza A, et al. Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors. Bioorg Med Chem. 2020 Feb 1;28(3):115257. DOI:10.1016/j.bmc.2019.115257

5-nitro-2-(4-nitrophenyl)-1H-benzimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

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5-nitro-2-(4-nitrophenyl)-1H-benzimidazole Suppliers

China 16 South Korea 1 United States 1 Global 18
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
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China
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30123
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Henan Lien Chemical Products Co., Ltd.
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03716091-9097 13383857418
Fax
03716091-9097
Email
1520689222@qq.com
Country
China
ProdList
4862
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58
Henan Lien Chemical Products Co., Ltd.
Tel
0371-63357898 15378766539
Email
535046669@qq.com
Country
China
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4641
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58
Beijing Haite lesk Technology Co., Ltd
Tel
15210893940; 15116916250
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QQ: 237008221
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chemistryliu@163.com
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China
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7327
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Energy Chemical
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021-58432009 400-005-6266
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021-58436166
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marketing@energy-chemical.com
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China
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44918
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Shanghai Chino Pharmaceutical Technology Co., Ltd
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021-021-51557188 15901710861
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QQ: 569058060
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sales@channelpharm.com
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China
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1228
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Bide Pharmatech Ltd.
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400-1647117 13681763483
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product02@bidepharm.com
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China
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59936
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Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
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029-029-81120477 17792793610
Email
1033@dideu.com
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China
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9935
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58
TargetMol Chemicals Inc.
Tel
4008200310
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marketing@tsbiochem.com
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China
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24961
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Nantong QuanYi Biotechnology Co., Ltd
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0513-66337626 18051384581
Email
sales@chemhifuture.com
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China
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5929
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58

1772-39-0, 5-nitro-2-(4-nitrophenyl)-1H-benzimidazoleRelated Search:

TIMTEC-BB SBB010040 4-(1H-BENZOIMIDAZOL-2-YL)-PHENYLAMINE 2-(4-NITRO-PHENYL)-1H-IMIDAZOLE 4-(1H-IMIDAZOL-2-YL)-PHENYLAMINE 2-(4-Aminophenyl)-1H-benzimidazol-5-amine 5-nitro-2-(4-nitrophenyl)-1H-benzimidazole

  • 5-nitro-2-(4-nitrophenyl)-1H-benzimidazole
  • 5-Nitro-2-(4-nitrophenyl)benziMidazole, 95%
  • 5-Nitro-2-(4-nitrophenyl)-1H-benzoimidazole
  • MMP2-IN-2
  • 6-Nitro-2-(4-nitrophenyl)-1H-benzo[d]imidazole
  • 1H-Benzimidazole, 6-nitro-2-(4-nitrophenyl)-
  • 1772-39-0