1-benzyl-4-piperidone oxime
- Product Name
- 1-benzyl-4-piperidone oxime
- CAS No.
- 949-69-9
- Chemical Name
- 1-benzyl-4-piperidone oxime
- Synonyms
- 1-benzyl-4-piperidon;Cinitapride Impurity 5;Cinitapride Impurity 14;1-benzyl-4-piperidone oxime;1-Benzylpiperidine-4-oneoxime;1-Benzyl-piperidin-4-one oxime;N-benzyl-4-(N-hydroxyimino)piperidine;4-Piperidinone,1-(phenylMethyl)-, oxiMe;N-(1-Benzylpiperidin-4-ylidene)hydroxylamine;N-benzyl 4- (N-hydroxyimine) piperidine, oxime
- CBNumber
- CB2928072
- Molecular Formula
- C12H16N2O
- Formula Weight
- 204.27
- MOL File
- 949-69-9.mol
1-benzyl-4-piperidone oxime Property
- Melting point:
- 126-128 °C(Solv: chloroform (67-66-3); ligroine (8032-32-4))
- Boiling point:
- 338.5±35.0 °C(Predicted)
- Density
- 1.12±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 12.14±0.20(Predicted)
- Appearance
- White to light yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- L478938
- Product name
- 1-BENZYL-4-PIPERIDINONE OXIME
- Purity
- AldrichCPR
- Packaging
- 10MG
- Price
- $30.7
- Updated
- 2025/07/31
- Product number
- B704078
- Product name
- 1-benzyl-piperidin-4-oneoxime
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- R147
- Product name
- 1-Benzyl-piperidin-4-oneoxime
- Packaging
- 10g
- Price
- $40
- Updated
- 2021/12/16
- Product number
- FB147939
- Product name
- 1-Benzyl-piperidin-4-oneoxime
- Packaging
- 100mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- FB147939
- Product name
- 1-Benzyl-piperidin-4-oneoxime
- Packaging
- 250mg
- Price
- $110
- Updated
- 2021/12/16
1-benzyl-4-piperidone oxime Chemical Properties,Usage,Production
Synthesis
3612-20-2
949-69-9
General procedure for the synthesis of (1-benzylpiperidin-4-) ketoxime from N-benzylpiperidone: N-benzylpiperidone (1.89 g, 10 mmol) was dissolved in 50 mL of anhydrous ethanol, potassium carbonate (2.76 g, 20 mmol) and hydroxylamine hydrochloride (1.04 g, 15 mmol) were added sequentially, and the reaction was stirred for 6 hours at room temperature. After completion of the reaction, the reaction mixture was concentrated and diluted by adding water. The aqueous phase was extracted with ethyl acetate, the organic phase was washed with saturated sodium chloride solution, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford (1-benzylpiperidin-4-)ketoxime (2.04 g, 100% yield) as a white solid, and mass spectrometry analysis showed MS: 205.0 [M + H]+.
References
[1] Patent: US2017/44187, 2017, A1. Location in patent: Paragraph 0086; 0087
[2] European Journal of Medicinal Chemistry, 2010, vol. 45, # 7, p. 2827 - 2840
[3] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 14, p. 4085 - 4090
[4] Tetrahedron, 1995, vol. 51, # 17, p. 5143 - 5156
[5] Journal of Medicinal Chemistry, 2013, vol. 56, # 22, p. 9089 - 9099
1-benzyl-4-piperidone oxime Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-benzyl-4-piperidone oxime manufacturers
- Product
- 1-benzyl-4-piperidone oxime 949-69-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-16
- Product
- 1-benzyl-4-piperidone oxime 949-69-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100
- Release date
- 2021-12-23
- Product
- 1-benzyl-4-piperidone oxime 949-69-9
- Price
- US $19.00/g
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5ton/Month
- Release date
- 2021-12-15