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Pivagabine

Product Name
Pivagabine
CAS No.
69542-93-4
Chemical Name
Pivagabine
Synonyms
Tonerg;CXB 722;Pivagabine;PG 2 (pharmaceutical);4-PivalaMidobutanoic acid;4-(Pivaloylamino)butanoic acid;N-trimethylacetyl-4-aminobutyric acid;4-(2,2-Dimethylpropionamido)butanoic acid;4-[(2,2-dimethylpropionyl)amino]butyric acid;Butanoic acid,4-[(2,2-diMethyl-1-oxopropyl)aMino]-
CBNumber
CB2928582
Molecular Formula
C9H17NO3
Formula Weight
187.24
MOL File
69542-93-4.mol
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Pivagabine Property

Boiling point:
397.0±25.0 °C(Predicted)
Density 
1.053±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in DMSO
pka
4.66±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D462238
Product name
4-(2,2-Dimethylpropionylamino)butyricAcid
Packaging
250mg
Price
$285
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0102236
Product name
4-[(2,2-DIMETHYLPROPANOYL)AMINO]BUTANOIC ACID
Purity
95.00%
Packaging
1G
Price
$852.55
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0102236
Product name
4-[(2,2-DIMETHYLPROPANOYL)AMINO]BUTANOIC ACID
Purity
95.00%
Packaging
2.5G
Price
$1227.82
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0102236
Product name
4-[(2,2-DIMETHYLPROPANOYL)AMINO]BUTANOIC ACID
Purity
95.00%
Packaging
5G
Price
$1548.26
Updated
2021/12/16
ChemScene
Product number
CS-0028165
Product name
Pivagabine
Packaging
5mg
Price
$95
Updated
2021/12/16
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Pivagabine Chemical Properties,Usage,Production

Description

Tonerg was launched in Italy for treatment of acute and post traumatic stress syndrome and "burnout" syndrome. It inhibits hypothalamic release of corticotropinreleasing factor (CRF) and effectively antagonizes the activation of CRF induced stress (neuroendocrine, autonomic and behavior responses). Tonerg is an atypical antidepressant because it does not involve the monoaminergic system and differs in effect from benzodiazepines (complete opposite effect of Diazepam). The entire molecule is responsible for activity. It is lipophilic, orally bioavailable, and has a halflife of 4-6 hr. Tonerg has a positive effect on sleep disorders by reducing insomnia, improving anxiety by 20% and depression by 23%.

Originator

Angelini (Italy)

Definition

ChEBI: Pivagabine is an organooxygen compound and an organonitrogen compound. It is functionally related to a gamma-amino acid.

brand name

Tonerg

Pivagabine Preparation Products And Raw materials

Raw materials

Preparation Products

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Pivagabine Suppliers

AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
15928766785 15928766785
Fax
QQ961458712
Email
wupengcheng@astatech.cn
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China
ProdList
1999
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
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China
ProdList
16687
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50
Zhengzhou Guancheng Laboratory equipment Sales
Tel
0371-88888888 272369594
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QQ:272369594
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2723695949@qq.com
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China
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5011
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SanoChem (Chengdu) Tech. Co., Ltd.
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28-87999436 02887999436
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QQ:2746983436
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sales@sano-chem.com
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China
ProdList
3929
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Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
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China
ProdList
131981
Advantage
58
Shanghai He Huan Chemical Co., Ltd.
Tel
021-60345187 13917602471
Fax
021-60345187
Email
lzz841106@aliyun.com
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China
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9908
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Suzhou Rovathin Foreign Trade Co.,Ltd
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0512-65816829 18662214788
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0512-65816829
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info@rovathin.com.cn
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China
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9385
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Baoji Guokang Healthchem co.,ltd
Tel
+8615604608665 15604608665
Email
dominicguo@gk-bio.com
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CHINA
ProdList
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767
Fax
QQ 3610331285
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China
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Chengdu Jiuding Chemical Technology Co., Ltd. - Song Bo
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Changzhou Kechem Bio-Scientific Co., LTD.
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0519-68985668 13685222090
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840
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psaitong@jm-bio.com
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Shanghai Haohong Pharmaceutical Co., Ltd.
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400-8210725 4008210725
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malulu@leyan.com
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39997
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Kaifeng Mingren Pharmaceutical Co.,LTD
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Changzhou Bojia Biomedical Technology Co., Ltd.
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2122619822
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czbjpharma@126.com
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Nanjing Wogni Chemical Co., Ltd.
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foxerhy@163.com
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TargetMol Chemicals Inc.
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Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
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Jining Yize Pharmaceutical Technology Co., Ltd
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RD International Technology Co., Limited
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9180
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Nanjing Finetech Chemical Co., Ltd.
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69542-93-4, PivagabineRelated Search:


  • 4-[(2,2-dimethylpropionyl)amino]butyric acid
  • 4-(Pivaloylamino)butanoic acid
  • 4-PivalaMidobutanoic acid
  • CXB 722
  • PG 2 (pharmaceutical)
  • Tonerg
  • Butanoic acid,4-[(2,2-diMethyl-1-oxopropyl)aMino]-
  • Pivagabine
  • N-trimethylacetyl-4-aminobutyric acid
  • 4-(2,2-Dimethylpropionamido)butanoic acid
  • Pivagabine,blood-brain,γ-Aminobutyric acid Receptor,psychoactive,CXB722,derivative,Inhibitor,inhibit,foot,factor,barrier,CXB 722,shock,Gamma-aminobutyric acid Receptor,GABA Receptor,neuromodulatory,corticotropin-releasing
  • 69542-93-4