Pivagabine
- Product Name
- Pivagabine
- CAS No.
- 69542-93-4
- Chemical Name
- Pivagabine
- Synonyms
- Tonerg;CXB 722;Pivagabine;PG 2 (pharmaceutical);4-PivalaMidobutanoic acid;4-(Pivaloylamino)butanoic acid;N-trimethylacetyl-4-aminobutyric acid;4-(2,2-Dimethylpropionamido)butanoic acid;4-[(2,2-dimethylpropionyl)amino]butyric acid;Butanoic acid,4-[(2,2-diMethyl-1-oxopropyl)aMino]-
- CBNumber
- CB2928582
- Molecular Formula
- C9H17NO3
- Formula Weight
- 187.24
- MOL File
- 69542-93-4.mol
Pivagabine Property
- Boiling point:
- 397.0±25.0 °C(Predicted)
- Density
- 1.053±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Soluble in DMSO
- pka
- 4.66±0.10(Predicted)
- form
- Solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D462238
- Product name
- 4-(2,2-Dimethylpropionylamino)butyricAcid
- Packaging
- 250mg
- Price
- $285
- Updated
- 2021/12/16
- Product number
- CHM0102236
- Product name
- 4-[(2,2-DIMETHYLPROPANOYL)AMINO]BUTANOIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $852.55
- Updated
- 2021/12/16
- Product number
- CHM0102236
- Product name
- 4-[(2,2-DIMETHYLPROPANOYL)AMINO]BUTANOIC ACID
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1227.82
- Updated
- 2021/12/16
- Product number
- CHM0102236
- Product name
- 4-[(2,2-DIMETHYLPROPANOYL)AMINO]BUTANOIC ACID
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1548.26
- Updated
- 2021/12/16
- Product number
- CS-0028165
- Product name
- Pivagabine
- Packaging
- 5mg
- Price
- $95
- Updated
- 2021/12/16
Pivagabine Chemical Properties,Usage,Production
Description
Tonerg was launched in Italy for treatment of acute and post traumatic stress syndrome and "burnout" syndrome. It inhibits hypothalamic release of corticotropinreleasing factor (CRF) and effectively antagonizes the activation of CRF induced stress (neuroendocrine, autonomic and behavior responses). Tonerg is an atypical antidepressant because it does not involve the monoaminergic system and differs in effect from benzodiazepines (complete opposite effect of Diazepam). The entire molecule is responsible for activity. It is lipophilic, orally bioavailable, and has a halflife of 4-6 hr. Tonerg has a positive effect on sleep disorders by reducing insomnia, improving anxiety by 20% and depression by 23%.
Originator
Angelini (Italy)
Definition
ChEBI: Pivagabine is an organooxygen compound and an organonitrogen compound. It is functionally related to a gamma-amino acid.
brand name
Tonerg
Pivagabine Preparation Products And Raw materials
Raw materials
Preparation Products
Pivagabine Suppliers
- Tel
- --
- Fax
- --
- enamine@enamine.net
- Country
- Ukraine
- ProdList
- 6216
- Advantage
- 67
- Tel
- --
- Fax
- --
- y.barysheva@ukrorgsynth.com
- Country
- Ukraine
- ProdList
- 6230
- Advantage
- 38
- Tel
- --
- Fax
- --
- north.america@otavachemicals.com
- Country
- Ukraine
- ProdList
- 6495
- Advantage
- 72