cis-4-(Trifluoromethyl)cyclohexanol
- Product Name
- cis-4-(Trifluoromethyl)cyclohexanol
- CAS No.
- 75091-92-8
- Chemical Name
- cis-4-(Trifluoromethyl)cyclohexanol
- Synonyms
- cis-4-(Trifluoromethyl)cyclohexanol;cis-4-(Trifluoromethyl)cyclohexan-1-ol;Cyclohexanol, 4-(trifluoroMethyl)-, cis-;(1S,4s)-4-(trifluoromethyl)cyclohexan-1-ol
- CBNumber
- CB2947268
- Molecular Formula
- C7H11F3O
- Formula Weight
- 168.16
- MOL File
- 75091-92-8.mol
cis-4-(Trifluoromethyl)cyclohexanol Property
- Boiling point:
- 160.4±35.0 °C(Predicted)
- Density
- 1.231±0.06 g/cm3(Predicted)
- storage temp.
- Store at Room Tem.
- pka
- 14.88±0.40(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P370+P378In case of fire: Use … for extinction.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
cis-4-(Trifluoromethyl)cyclohexanol Chemical Properties,Usage,Production
Synthesis
402-45-9
75091-92-8
Step A: Synthesis of 4-(trifluoromethyl)cyclohexanol; 4-hydroxytrifluorotoluene (5 g, 30.8 mmol) was placed in a high-pressure hydrogenation reactor, dissolved in acetic acid (15 ml) and platinum oxide (PtO, 500 mg) was added as a catalyst. The reactor was pressurized using hydrogen (50 psi) and the reaction was carried out at room temperature for 16 hours. Upon completion of the reaction, the reaction mixture was filtered through a diatomaceous earth pad to remove the catalyst, and the pH was adjusted by adding 1N sodium hydroxide solution to the filtrate, which was subsequently extracted with diethyl ether. The organic phase was dried over anhydrous magnesium sulfate (MgSO4) and concentrated under reduced pressure at room temperature to afford cis-4-(trifluoromethyl)cyclohexanol (4.5 g, 87% yield). Mass spectrometry analysis showed [M + H]+ peak of 169, corresponding to the molecular ion peak (M + 1) of the target compound.
References
[1] Patent: WO2008/7930, 2008, A1. Location in patent: Page/Page column 27
[2] , 1970, vol. 6, # 10, p. 2063 - 2067
[3] Zhurnal Organicheskoi Khimii, 1970, vol. 6, # 10, p. 2055 - 2060
cis-4-(Trifluoromethyl)cyclohexanol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from cis-4-(Trifluoromethyl)cyclohexanol manufacturers
- Product
- cis-4-(Trifluoromethyl)cyclohexanol 75091-92-8
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-24
- Product
- CIS-4-(TRIFLUOROMETHYL)CYCLOHEXANOL 75091-92-8
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 200kg/month
- Release date
- 2020-11-03
- Product
- cis-4-(Trifluoromethyl)cyclohexanol 75091-92-8
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99.9%
- Supply Ability
- 20tons
- Release date
- 2020-09-22