5-Aminopyridine-2-carboxamide
- Product Name
- 5-Aminopyridine-2-carboxamide
- CAS No.
- 145255-19-2
- Chemical Name
- 5-Aminopyridine-2-carboxamide
- Synonyms
- 5-AMinopicolinaMide;5-Aminopyridine-2-carboxamide;5-AMino-2-pyridine carboxaMide;2-Pyridinecarboxamide, 5-amino-;2-Pyridinecarboxamide,5-amino-(9CI);5-AMINOPYRIDINE-2-CARBOXAMIDE,PURITY;5-aminopyridine-2-carboxylic acid amide;5-Aminopyridine-2-carboxamide ISO 9001:2015 REACH;5-AMINOPYRIDINE-2-CARBOXAMIDE,PURITY:95% MIN(HPLC)
- CBNumber
- CB2947758
- Molecular Formula
- C6H7N3O
- Formula Weight
- 137.14
- MOL File
- 145255-19-2.mol
5-Aminopyridine-2-carboxamide Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- Appearance
- Light yellow to light brown Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A616620
- Product name
- 5-Aminopyridine-2-carboxamide
- Packaging
- 1g
- Price
- $235
- Updated
- 2021/12/16
- Product number
- FA144413
- Product name
- 5-Aminopicolinamide
- Packaging
- 500mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- FA144413
- Product name
- 5-Aminopicolinamide
- Packaging
- 100mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- FA144413
- Product name
- 5-Aminopicolinamide
- Packaging
- 250mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- 076515
- Product name
- 5-Aminopyridine-2-carboxamide
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $278
- Updated
- 2021/12/16
5-Aminopyridine-2-carboxamide Chemical Properties,Usage,Production
Uses
5-Aminopyridine-2-carboxamide is a synthetic building block used as a reactant in the discovery of carboline analogs as potent MAPKAP-K2 inhibitors.
Synthesis
55338-73-3
145255-19-2
General procedure for the synthesis of 5-amino-2-pyridinecarboxamide from 3-amino-6-cyanopyridine: To an 18 mL reaction vial was added a mixed solution of 30% H2O2 (1 mL), 3 N NaOH (3 mL) and MeOH (2.5 mL). To the above mixed solution was added 3-amino-6-cyanopyridine (450 mg, 3.78 mmol) at room temperature. The reaction mixture was stirred at room temperature for 45 minutes and the progress of the reaction was monitored by thin layer chromatography (TLC) to confirm complete consumption of the ingredients. Upon completion of the reaction, the mixture was diluted with water and filtered to collect the solid product. The solid was washed with deionized water and dried to give 480 mg of 5-amino-2-pyridinecarboxamide in 92% yield.
References
[1] Patent: US9138427, 2015, B2. Location in patent: Page/Page column 287
[2] Journal of Medicinal Chemistry, 1994, vol. 37, # 1, p. 18 - 25
[3] Patent: WO2006/17443, 2006, A2. Location in patent: Page/Page column 151
5-Aminopyridine-2-carboxamide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Aminopyridine-2-carboxamide manufacturers
- Product
- 5-Aminopyridine-2-carboxamide 145255-19-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-27
- Product
- 5-Aminopyridine-2-carboxamide 145255-19-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 5-Aminopyridine-2-carboxamide 145255-19-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08