Melanotan II acetate
- Product Name
- Melanotan II acetate
- Chemical Name
- Melanotan II acetate
- CBNumber
- CB2947970
- Formula Weight
- 0
- MOL File
- Mol file
Melanotan II acetate Property
- solubility
- DMF: 30 mg/ml
DMF: PBS (pH 7.2) (1:4): 0.20 mg/ml
DMSO: 15 mg/ml
Ethanol: 1 mg/ml
N-Bromosuccinimide Price
- Product number
- 27316
- Product name
- Melanotan II (acetate)
- Packaging
- 1mg
- Price
- $153
- Updated
- 2024/03/01
- Product number
- 27316
- Product name
- Melanotan II (acetate)
- Packaging
- 5mg
- Price
- $684
- Updated
- 2024/03/01
- Product number
- CHM0091905
- Product name
- MELANOTAN II ACETATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.27
- Updated
- 2021/12/16
Melanotan II acetate Chemical Properties,Usage,Production
Description
Melanotan II is an agonist of melanocortin receptor 1 (MC1R), MC3R, MC4R, and MC5R (Kis = 0.67, 34, 6.6, and 46 nM, respectively, in COS cells expressing human recombinant receptors).1 It improves recovery of sciatic nerve function after mechanical injury in rats, and increases cisplatin-induced decreases in sensory nerve conduction velocity when administered at a dose of 20, but not 2 or 50, µg/kg.2 Melanotan II (1 nmol, i.c.v.) increases oxygen consumption and protein levels of uncoupling protein 1 (UCP1) in brown adipose tissue homogenates and decreases food intake, body weight, and serum levels of leptin, glucose, insulin, and cholesterol (Item No. 9003100) in chow-fed and diet-induced obese rats.3WARNING This product is not for human or veterinary use.
References
[1] HELGI B SCHIÖTH . Selectivity of Cyclic [d-Nal7] and [d-Phe7] Substituted MSH Analogues for the Melanocortin Receptor Subtypes[J]. Peptides, 1997, 18 7: Pages 1009-1013. DOI: 10.1016/s0196-9781(97)00079-x
[2] MARIËL P TER LAAK. The potent melanocortin receptor agonist melanotan-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat[J]. European journal of pharmacology, 2003, 462 1: Pages 179-183. DOI: 10.1016/s0014-2999(02)02945-x
[3] G LI. Unabated anorexic and enhanced thermogenic responses to melanotan II in diet-induced obese rats despite reduced melanocortin 3 and 4 receptor expression.[J]. Journal of Endocrinology, 2004, 182 1: 123-132. DOI: 10.1677/joe.0.1820123
Melanotan II acetate Preparation Products And Raw materials
Raw materials
Preparation Products
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