ChemicalBook > CAS DataBase List > 3-Bromo-L-phenylalanine

3-Bromo-L-phenylalanine

Uses

Product Name: 3-Bromo-L-phenylalanine
CAS No.: 82311-69-1
Chemical Name: 3-Bromo-L-phenylalanine
Synonyms: L-3-Br-phe;L-3-BR-PHE-OH;3-Br-L-Phe-OH;L-Phe(3-Br)-OH;RRSYY(Avadomide)-5;(L)-Bromophenyl alanine;m-Bromo-L-phenylalanine;3-Bromo-L-phenylalanine;L-Phenylalanine, 3-bromo-;3-Bromo-L-phenylalanine,95%
CBNumber: CB2948139
Molecular Formula: C9H10BrNO2
Formula Weight: 244.09
MOL File: 82311-69-1.mol

Less

3-Bromo-L-phenylalanine Property

Boiling point:: 368.4±32.0 °C(Predicted)
Density: 1.588±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 2.16±0.10(Predicted)
form: solid
color: White to off white
optical activity: Consistent with structure
Water Solubility: Slightly soluble in water.

Less

Safety

HS Code: 2922498590

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

Less

N-Bromosuccinimide Price

TRC

Product number: B789320
Product name: 3-Bromo-L-phenylalanine
Packaging: 250mg
Price: $40
Updated: 2021/12/16

TRC

Product number: B789320
Product name: 3-Bromo-L-phenylalanine
Packaging: 1g
Price: $65
Updated: 2021/12/16

Usbiological

Product number: 265342
Product name: 3-Bromo- L-phenylalanine
Packaging: 1g
Price: $379
Updated: 2021/12/16

Activate Scientific

Product number: AS39494
Product name: (S)-2-Amino-3-(3-bromophenyl)propanoic acid
Purity: 98% ee
Packaging: 1g
Price: $16
Updated: 2021/12/16

Chem-Impex

Product number: 14322
Product name: 3-Bromo- L-phenylalanine
Purity: ≥ 99% (HPLC)
Packaging: 250MG
Price: $30
Updated: 2021/12/16

Less

3-Bromo-L-phenylalanine Chemical Properties,Usage,Production

Uses

3-Bromo-L-phenylalanine is used in preparation of lifitegrast intermediate.

Chemical Properties

White to off-white powder

Uses

It is applied in the facile removal of leader peptides from lanthipeptides by incorporation of a hydroxy acid.

Uses

3-Bromo-L-phenylalanine is used in preparation of lifitegrast intermediate.

Synthesis

82278-73-7

82311-69-1

The general procedure for the synthesis of (S)-2-amino-3-(3-bromophenyl)propionic acid from (S)-3-(3-bromophenyl)-2-((tert-butoxycarbonyl)amino)propionic acid was as follows: (S)-3-(3-bromophenyl)-2-((tert-butoxycarbonyl)amino)propionic acid (5.0 g, 14.5 mmol) was suspended in a 1,4-dioxane solution of 4 M hydrochloric acid (75 mL ) and the reaction was stirred at room temperature for 16 hours. Upon completion of the reaction, the white precipitate was collected by filtration and washed with ether (Et2O) to afford (S)-2-amino-3-(3-bromophenyl)propionic acid (3.2 g, 89% yield) as a white solid, and the product did not require further purification. The nuclear magnetic resonance hydrogen spectrum (1H NMR, CDCl3) data of the product were as follows: δ 8.32 (2H, s), 7.50-7.48 (2H, m), 7.34-7.29 (2H, m), 4.22 (1H, t, J=6.2 Hz), 3.13-3.11 (2H, m).

References

[1] Patent: WO2008/47109, 2008, A1. Location in patent: Page/Page column 42
[2] Patent: WO2006/114606, 2006, A1. Location in patent: Page/Page column 61

3-Bromo-L-phenylalanine Preparation Products And Raw materials

Raw materials

Preparation Products

Less

3-Bromo-L-phenylalanine Suppliers

China 162 Germany 1 India 1 United Kingdom 3 United States 9 Global 176

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Shanghai HC Biotech Co., Ltd

Tel: 021-20227858
Fax: +86-21-20227857
Email: sale@hcbiotech.com.cn
Country: China
ProdList: 1095
Advantage: 55

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Suzhou haiyu Biochem Industrial Co., LTD

Tel: 512-68097639 18013585858
Fax: 0512-
Email: 744942877@qq.com
Country: China
ProdList: 915
Advantage: 62

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Shenzhen Sungening Bio-Tech Co., Ltd

Tel: +86-0755-89668383
Fax: +86-0755-89594066/4038
Email: sales@sungening.com
Country: China
ProdList: 1319
Advantage: 65

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7782
Advantage: 58

DONGSHENG CHIRAL PHARMA

Tel: 15800326364 18051538752
Email: 582512789@qq.com
Country: China
ProdList: 449
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9874
Advantage: 55

Taizhou Tongxin Bio-Tech Co., Ltd

Tel: 0523-86818997 18652728585
Email: sales@allyrise.com
Country: China
ProdList: 2966
Advantage: 60

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9637
Advantage: 58

NINGBO INNO PHARMCHEM CO.,LTD.

Tel: 86-574-27787657
Fax: 86-574-27912196
Email: info@dearchem.com
Country: China
ProdList: 4613
Advantage: 58

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

Shanghai Yongye Biotechnology Co., Ltd.

Tel: 86-021-61559134 15921386130
Fax: 021-55068248
Email: 3423497944@qq.com
Country: China
ProdList: 8144
Advantage: 55

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16679
Advantage: 50

Chengdu Miracle Pharmaceutical Co., Ltd.

Tel: 028-86136736 19130631884
Fax: 028-85265615
Email: sales@mic-pharma.com
Country: China
ProdList: 337
Advantage: 56

Changzhou Anxuan Chemical, Co., Ltd.

Tel: 13912302692 13912302692;
Fax: 0519-88064678
Email: sales@anxuanchem.com
Country: China
ProdList: 4828
Advantage: 58

Nanjing Endesa Bio-tech Co., Ltd.

Tel: 025-58862853 18915922038
Fax: +86-025-58862853
Email: sales@endesachem.com
Country: China
ProdList: 591
Advantage: 58

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

skychemical Co.Ltd

Tel: 021-20960837,QQ1332204249
Fax: 021-20960837
Email: sales@skychemical.com
Country: China
ProdList: 3341
Advantage: 55

Shanghai GL Peptide Ltd.

Tel: +86-21-61263340; 17609490614 13764994101
Fax: 021-61263399
Email: fisherwang@glschina.com
Country: China
ProdList: 8258
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai QianYan Bio-technology Co., Ltd

Tel: 02781293128
Email: orders@biochemsafebuy.com
Country: China
ProdList: 9923
Advantage: 55

parabiochem

Tel: 025-83453382-8005
Fax: 025-83453382
Email: sale@parabiochem.com
Country: China
ProdList: 9595
Advantage: 55

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20794
Advantage: 60

Wuxi Asia Peptide Biotechnology Limited Company

Tel: 0510-83583050 13771062561
Fax: 0510-83583039
Email: willsun@peptide-search.com
Country: China
ProdList: 6716
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Nanjing Peptide Biotech Ltd.

Tel: 025-58361106-805 15951641583
Fax: 025-58361106-806
Email: zhao.xu@njpeptide.com
Country: China
ProdList: 9979
Advantage: 55

Guangzhou Jhd Chemical Reagent Co., Ltd.

Tel: 020-84383047
Fax: 020-84380294
Email: sales@jhd.com.cn
Country: China
ProdList: 9186
Advantage: 65

Sichuan jiayinglai technology CO.,LTD

Tel: 028-028-88457210 18190964009
Fax: QQ3213375147
Email: 3054240163@qq.com
Country: China
ProdList: 2293
Advantage: 55

Hangzhou Molcore Biopharmatech Co.,Ltd

Tel: 400-711-5280 86-571-81025280
Fax: 86-571-85806285
Email: sales@molcore.com
Country: China
ProdList: 9967
Advantage: 58

Chiral Quest (Suzhou) Co., Ltd.

Tel: 0512-62956066 18112603058
Email: kendoll@cqpharm.com
Country: China
ProdList: 96
Advantage: 58

Jiaxing Deyi Chemical Co., Ltd.

Tel: 86-0573-85866609 13325730825
Fax: 0573-85866609
Email: 945717149@qq.com
Country: China
ProdList: 8595
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

Abydos Scientific

Tel: 025-84767922 18936879710
Email: sales@abydoscientific.com
Country: China
ProdList: 1002
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Cool Pharm, Ltd

Tel: 021-58581007 18019463053
Fax: 021-50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12878
Advantage: 58

Less

View Lastest Price from 3-Bromo-L-phenylalanine manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 3-Bromo-L-phenylalanine 82311-69-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-30

Career Henan Chemical Co

Product: 3-Bromo-L-phenylalanine 82311-69-1
Price: US $100.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2018-07-30

82311-69-1, 3-Bromo-L-phenylalanineRelated Search:

(2S)-2-amino-3-(3-carbamoylphenyl)propanoic acid L-3-Chlorophenylalanine FMOC-D-4-THIAZOLYLALANINE L-3-Cyanophenylalanine L-3-AMINOMETHYLPHE 4-Bromo-D-phenylalanine, N-BOC protected,N-alpha-t-Butyloxycarbonyl-4-bromo-D-phenylalanine,BOC-4-BROMO-D-PHENYLALANINE,BOC-P-BROMO-D-PHENYLALANINE FMOC-3-BROMO-L-PHENYLALANINE BOC-3-BROMO-L-PHENYLALANINE 2-BROMO-L-PHENYLALANINE BOC-(R)-4-BROMO-BETA-PHENYLALANINE FMOC-(S)-4-BROMO-BETA-PHENYLALANINE BOC-(S)-4-BROMO-BETA-PHENYLALANINE FMOC-2-BROMO-L-PHENYLALANINE,N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-2-BROMO-L-PHENYLALANINE 3-BROMO-DL-PHENYLALANINE 4-BROMO-D-PHENYLALANINE BOC-2-BROMO-L-PHENYLALANINE BOC-2-BROMO-D-PHENYLALANINE 4-BROMO-DL-PHENYLALANINE,4-Bromo-DL-phenylalanine, 98+%

3-Bromo-L-phenylalanine

(S)-2-Amino-3-(3'-Bromophenyl)Propanoic Acid

(L)-Bromophenyl alanine

3-Br-L-Phe-OH

(S)-2-((3-bromophenyl)amino)propanoic acid

L-Phe(3-Br)-OH

m-Bromo-L-phenylalanine

L-3-BR-PHE-OH

L-3-Br-phe

L-Phenylalanine, 3-bromo-

3-Bromo-L-phenylalanine,95%

3-Bromo-L-phenylalanine USP/EP/BP

RRSYY(Avadomide)-5

82311-69-1

Amino Acid Derivatives

Amino Acids