Epoprostenol

Product Name: Epoprostenol
CAS No.: 35121-78-9
Chemical Name: Epoprostenol
Synonyms: PGX;PGl2;U 53217;U-53217A;Vasocyclin;Cyclo-Prostin;ProstaglandinI;(+)-Alismoxide;Prostaglandin X;Prostaglandin l2
CBNumber: CB2969864
Molecular Formula: C20H32O5
Formula Weight: 352.47
MOL File: 35121-78-9.mol

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Epoprostenol Property

Boiling point:: 530.2±50.0 °C(Predicted)
Density: 1.221
pka: 4.70±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Medical Isotopes, Inc.

Product number: 18622
Product name: Epoprostenol
Packaging: 5mg
Price: $950
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0002571
Product name: EPOPROSTENOL
Purity: 95.00%
Packaging: 10MG
Price: $1000.52
Updated: 2021/12/16

AvaChem

Product number: 2641
Product name: Epoprostenol
Packaging: 100mg
Price: $1490
Updated: 2021/12/16

AvaChem

Product number: 2641
Product name: Epoprostenol
Packaging: 10mg
Price: $349
Updated: 2021/12/16

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Epoprostenol Chemical Properties,Usage,Production

Originator

Prostacyclin,ZYF Pharm Chemical

Uses

Inhibitor (platelet). [Names previously used: Prostacyclin, PGI2, Prostagland in I2, Prostaglandin X, PGX].

Definition

ChEBI: Prostaglandin I2 is a prostaglandins I. It has a role as a mouse metabolite. It is a conjugate acid of a prostaglandin I2(1-).

Manufacturing Process

Preparation of prostacyclin:
Pig aortas were stripped of adventitia, snap frozen in liquid nitrogen, crushed into a fine powder, resuspended in 0.05 M Tris buffer (pH 7.5) (1:4, w:v) andhomogenised at high speed in a Polytron (KIMENATIC, LUCERNE, SWITZERLAND) homogenizer. The homogenate was centrifuged for 15 min and the resulting supernatant centrifuged again for 5 min. The pellet was discarded, while the pellet obtained after centrifugation of the supernatant was resuspended in deionized water and lyophilized. An average yield of 150 mg of aortic microsomal powder (51% protein) per 100 g of aortic tissue was obtained.

brand name

Flolan (GlaxoSmithKline).

Therapeutic Function

Platelet aggregation inhibitor, Antimetastatic

Epoprostenol Preparation Products And Raw materials

Raw materials

Potassium tert-butoxide

Preparation Products

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Epoprostenol Suppliers

China 26 India 5 South Korea 1 United States 7 Global 39

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35121-78-9, EpoprostenolRelated Search:

Angiotensin Aprepitant Fludarabine phosphate Carboprost tromethamine Latanoprost Pipecuronium bromide PROMETHAZINE REMODULIN Prostaglandin E1 Beraprost PROSTACYCLIN SODIUM SALT

(5z,13e)-(15s)-6,9-alpha-epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoate

5Z13E-15S-69-ALPHA-EPOXY-11-ALPHA

PGX(prostaglandin)

ProstaglandinI

5-[7-hydroxy-8-(3-hydroxyoct-1-enyl)-4-oxabicyclo[3.3.0]oct-3-ylidene]pentanoic acid

6(9)-Oxy-11,15-dihydroxyprosta-5,13-dienoic acid

PGX

Prostaglandin X

U 53217

Vasocyclin

(5Z，9α，11α，13E，15S)-6，9-Epoxy-11，15-dihydroxyprosta-5，13-dien-1-oicacid

Cyclo-Prostin

PGl2

Prostaglandin l2

U-53217A

Prostacyclin (Epoprostenol)

Epoprostenol USP/EP/BP

(+)-Alismoxide

Prosta-5,13-dien-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (5Z,9α,11α,13E,15S)-

35121-78-9

API