PROSTACYCLIN SODIUM SALT
- Product Name
- PROSTACYCLIN SODIUM SALT
- CAS No.
- 61849-14-7
- Chemical Name
- PROSTACYCLIN SODIUM SALT
- Synonyms
- PGI2;Flolan;PG12-NA;PGI2-NA;PGI2 sodium;Sodium PGI2;EPOPROSTENOL;Eprostol sodium;PROSTAGLANDIN I2;Prostaglandin 12
- CBNumber
- CB8167138
- Molecular Formula
- C20H33NaO5
- Formula Weight
- 376.47
- MOL File
- 61849-14-7.mol
PROSTACYCLIN SODIUM SALT Property
- Melting point:
- 168-170 °C
- RTECS
- UK8008700
- storage temp.
- -20°C
- solubility
- H2O: 1 mg/mL Hydrolyzes to 6-ketoprostaglandin F1α in aqueous solution.
- form
- powder
- color
- white
- Water Solubility
- Soluble to 100 mM in water
- Sensitive
- Moisture Sensitive
- Merck
- 13,7967
- BRN
- 6472195
- Stability:
- Light Sensitive, Temperature Sensitive
- CAS DataBase Reference
- 61849-14-7(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P321Specific treatment (see … on this label).
N-Bromosuccinimide Price
- Product number
- 1237600
- Product name
- Epoprostenol sodium
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 100mg
- Price
- $3490
- Updated
- 2024/03/01
- Product number
- J67115
- Product name
- Prostaglandin I2 sodium salt, 99%
- Packaging
- 1mg
- Price
- $159
- Updated
- 2023/06/20
- Product number
- 18220
- Product name
- Prostaglandin I2 (sodium salt)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $73
- Updated
- 2024/03/01
- Product number
- 18220
- Product name
- Prostaglandin I2 (sodium salt)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $324
- Updated
- 2024/03/01
- Product number
- P6188
- Product name
- Prostaglandin I2 sodium salt
- Purity
- ≥96% (HPLC), synthetic, powder
- Packaging
- 1mg
- Price
- $435
- Updated
- 2024/03/01
PROSTACYCLIN SODIUM SALT Chemical Properties,Usage,Production
Description
Epoprostenol is a naturally occurring prostaglandin indicated for the preservation of platelet function during cardiopulmonary bypass, prevention of platelet aggregation during charcoal hemoperfusion of patients in hepatic failure, and as an alternative to heparin during renal dialysis.
Chemical Properties
Epoprostenol is white crystalline powder
Originator
Burroughs Wellcome (United Kingdom)
Uses
Prostaglandin I2 sodium salt has been used:
- in the preparation of stock solution for platelet washing procedure
- as supplement in platelet-rich-plasma, for platelet preparation
- to prevent platelet activation
Uses
Epoprostenol is an Eicosanoid which prevents the formation of platelet plugs and is an effective vasodilator.
Manufacturing Process
Preparation of prostacyclin:
Pig aortas were stripped of adventitia, snap frozen in liquid nitrogen, crushed
into a fine powder, resuspended in 0.05 M Tris buffer (pH 7.5) (1:4, w:v) andhomogenised at high speed in a Polytron (KIMENATIC, LUCERNE,
SWITZERLAND) homogenizer. The homogenate was centrifuged for 15 min
and the resulting supernatant centrifuged again for 5 min. The pellet was
discarded, while the pellet obtained after centrifugation of the supernatant
was resuspended in deionized water and lyophilized. An average yield of 150
mg of aortic microsomal powder (51% protein) per 100 g of aortic tissue was
obtained.
brand name
Flolan (GlaxoSmithKline);CYCLO-PROSTIN.
Therapeutic Function
Platelet aggregation inhibitor, Antimetastatic
Biological Activity
Epoprostenol is a potent agonist at IP prostanoid receptors. Inhibits platelet aggregation and induces vasodilation.
Biochem/physiol Actions
Prostacyclin therapy improves hemodynamics in pulmonary arterial hypertension.
storage
Desiccate at -80°C
PROSTACYCLIN SODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from PROSTACYCLIN SODIUM SALT manufacturers
- Product
- PROSTACYCLIN SODIUM SALT 61849-14-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 25kg
- Release date
- 2019-07-12