PROSTACYCLIN SODIUM SALT

Product Name: PROSTACYCLIN SODIUM SALT
CAS No.: 61849-14-7
Chemical Name: PROSTACYCLIN SODIUM SALT
Synonyms: PGI2;Flolan;PG12-NA;PGI2-NA;PGI2 sodium;Sodium PGI2;EPOPROSTENOL;Eprostol sodium;PROSTAGLANDIN I2;Prostaglandin 12
CBNumber: CB8167138
Molecular Formula: C20H33NaO5
Formula Weight: 376.47
MOL File: 61849-14-7.mol

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PROSTACYCLIN SODIUM SALT Property

Melting point:: 168-170 °C
RTECS: UK8008700
storage temp.: -20°C
solubility: H₂O: 1 mg/mL Hydrolyzes to 6-ketoprostaglandin F_1α in aqueous solution.
form: powder
color: white
Water Solubility: Soluble to 100 mM in water
Sensitive: Moisture Sensitive
Merck: 13,7967
BRN: 6472195
Stability:: Light Sensitive, Temperature Sensitive
CAS DataBase Reference: 61849-14-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22
Safety Statements: 22-26-36
WGK Germany: 3
F: 3-10
HS Code: 29329900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P321Specific treatment (see … on this label).

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1237600
Product name: Epoprostenol sodium
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 100mg
Price: $3490
Updated: 2024/03/01

Alfa Aesar

Product number: J67115
Product name: Prostaglandin I2 sodium salt, 99%
Packaging: 1mg
Price: $159
Updated: 2023/06/20

Cayman Chemical

Product number: 18220
Product name: Prostaglandin I2 (sodium salt)
Purity: ≥98%
Packaging: 1mg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 18220
Product name: Prostaglandin I2 (sodium salt)
Purity: ≥98%
Packaging: 5mg
Price: $324
Updated: 2024/03/01

Sigma-Aldrich

Product number: P6188
Product name: Prostaglandin I2 sodium salt
Purity: ≥96% (HPLC), synthetic, powder
Packaging: 1mg
Price: $435
Updated: 2024/03/01

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PROSTACYCLIN SODIUM SALT Chemical Properties,Usage,Production

Description

Epoprostenol is a naturally occurring prostaglandin indicated for the preservation of platelet function during cardiopulmonary bypass, prevention of platelet aggregation during charcoal hemoperfusion of patients in hepatic failure, and as an alternative to heparin during renal dialysis.

Chemical Properties

Epoprostenol is white crystalline powder

Originator

Burroughs Wellcome (United Kingdom)

Uses

Prostaglandin I2 sodium salt has been used:

in the preparation of stock solution for platelet washing procedure
as supplement in platelet-rich-plasma, for platelet preparation
to prevent platelet activation

Uses

Epoprostenol is an Eicosanoid which prevents the formation of platelet plugs and is an effective vasodilator.

Manufacturing Process

Preparation of prostacyclin:
Pig aortas were stripped of adventitia, snap frozen in liquid nitrogen, crushed into a fine powder, resuspended in 0.05 M Tris buffer (pH 7.5) (1:4, w:v) andhomogenised at high speed in a Polytron (KIMENATIC, LUCERNE, SWITZERLAND) homogenizer. The homogenate was centrifuged for 15 min and the resulting supernatant centrifuged again for 5 min. The pellet was discarded, while the pellet obtained after centrifugation of the supernatant was resuspended in deionized water and lyophilized. An average yield of 150 mg of aortic microsomal powder (51% protein) per 100 g of aortic tissue was obtained.

brand name

Flolan (GlaxoSmithKline);CYCLO-PROSTIN.

Therapeutic Function

Platelet aggregation inhibitor, Antimetastatic

Biological Activity

Epoprostenol is a potent agonist at IP prostanoid receptors. Inhibits platelet aggregation and induces vasodilation.

Biochem/physiol Actions

Prostacyclin therapy improves hemodynamics in pulmonary arterial hypertension.

storage

Desiccate at -80°C

PROSTACYCLIN SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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PROSTACYCLIN SODIUM SALT Suppliers

Belgium 2 Canada 1 China 91 Czech Republic 2 Europe 2 France 1 Germany 2 Greece 1 India 13 Japan 3 South Korea 1 Switzerland 3 United Arab Emirates 1 United Kingdom 7 United States 31 Global 161

J & K SCIENTIFIC LTD.

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INTATRADE GmbH

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China Nobel Chem Co., Limited

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View Lastest Price from PROSTACYCLIN SODIUM SALT manufacturers

Dideu Industries Group Limited

Product: PROSTACYCLIN SODIUM SALT 61849-14-7
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-06-11

Career Henan Chemical Co

Product: PROSTACYCLIN SODIUM SALT 61849-14-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 25kg
Release date: 2019-07-12

61849-14-7, PROSTACYCLIN SODIUM SALTRelated Search:

PROSTAGLANDIN F1ALPHA Latanoprost Misoprostol Acid REMODULIN 5-Aminosalicylic acid 13,14-DIHYDROPROSTAGLANDIN E1 Prostaglandin F2a PROSTAGLANDIN D2 6(R)-(4-CARBOXYPHENYLTHIO)-5(S)-HYDROXY-7(E),9(E),11(Z),14(Z)-EICOSATETRAENOIC ACID L-161,982 11BETA-PROSTAGL AND IN F2ALPHA LEUKOTRIENE B4 DIMETHYL AMIDE LEUKOTRIENE D4 Epoprostenol PROSTACYCLIN SODIUM SALT 5-CAPROLEIC ACID 5-TRANS PROSTAGLANDIN F2ALPHA PROSTACYCLIN

EPOPROSTENOL

EPOPROSTENOL SODIUM

EPOPROSTENOL SODIUM SALT

(5-Z)-9-DEOXY-6,9ALPHA-EPOXY-PGF1ALPHA, SODIUM SALT

[5Z,9ALPHA,11ALPHA,13E,15S]-6,9-EPOXY-11,15-DIHYDROXYPROSTA-5,13-DIEN-1-OIC ACID SODIUM SALT

6,9ALPHA-EPOXY-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID, SODIUM SALT

PROSTACYCLINE SODIUM SALT

PROSTACYCLIN SODIUM SALT

PROSTAGLANDINS I2 SODIUM SALT

PROSTAGLANDIN I2

PROSTAGLANDIN I2 NA

PROSTAGLANDIN I2 SODIUM SALT

PG12-NA

PGI2

PGI2-NA

PGI2, SODIUM SALT

(5z,9α,11α,13e,15s)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt

Flolan

PGI2 sodium

Prosta-5,13-dien-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, monosodium salt, (5Z,9α,11α,13E,15S)-

Prostacyclin sodium

Sodium PGI2

Sodium prostacyclin

Epoprostenol sodium salt, PGI2-Na, Prostacyclin sodium salt, (5Z,9α,11α,13E,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt

sodium (5Z,13E,15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dien-1-oate

PROSTAGLANDIN I2 SODIUM

Prostaglandin 12

(5-Z)-9-DEOXY-6,9ALPHA-EPOXY-PGF1ALPHA, SODIUM SALT, 98%, STABILIZED

(5-Z)-9-Deoxy-6,9alpha-epoxy-PGF1alpha, sodium salt, stabilized

Sodium (5Z,13E,15S)-6,9a-epoxy-11a,15-dihydroxyprosta-5,13-dien-1-oate

cGMP Epoprostenol (sodium salt)

(5Z,13E,8R,9S,11R,12R,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oicacidsodiumsalt

Prostacyclin sodium salt Epoprostenol sodium

PGI2Na (Prostaglandin I2Na, Prostacyclin)

Prostaglandin I?, Sodium Salt

(5Z)-5-[(3aR,4R,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]pentanoate

Prostaglandin I, Sodium Salt - CAS 61849-14-7 - Calbiochem

PROSTACYCLIN SODIUM SALT USP/EP/BP

Epoprostenol ELISA Kit

Epoprostenol sodiumQ: What is Epoprostenol sodium Q: What is the CAS Number of Epoprostenol sodium Q: What is the storage condition of Epoprostenol sodium Q: What are the applications of Epoprostenol sodium

TIANFU CHEM--PROSTACYCLIN SODIUM SALT

Epoprostenol Sodium (COLD SHIPMENT REQUIRED) (1237600)

Eprostol sodium

61849-14-7

C20H32NaO5

C20H31O5Na

C20H31NaO5

Fatty Acids

Lipids

Prostaglandins

Biochemicals and Reagents

BioChemical

Chiral Reagents

Intermediates & Fine Chemicals

Pharmaceuticals