LEUKOTRIENE D4

Product Name: LEUKOTRIENE D4
CAS No.: 73836-78-9
Chemical Name: LEUKOTRIENE D4
Synonyms: LTD4;leukotriened;LEUKOTRIENE D4;leukotriened(sub4);LTD4 (Leukotriene D4);Leukotriene D4 (LTD4);YEESKJGWJFYOOK-IJHYULJSSA-N;(r-(r*,s*-(e,e,z,z)))-inyl);Leukotriene D4 MaxSpecStandard;LEUKOTRIENE D4 (ETHANOL SOLUTION)
CBNumber: CB1283439
Molecular Formula: C25H40N2O6S
Formula Weight: 496.66
MOL File: 73836-78-9.mol

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LEUKOTRIENE D4 Property

Boiling point:: 785.8±60.0 °C(Predicted)
Density: 1.162±0.06 g/cm3(Predicted)
Flash point:: 9℃
storage temp.: -70°C
solubility: A solution in ethanol
form: Liquid.
pka: 3.03±0.10(Predicted)
color: Colorless to light yellow

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Safety

Hazard Codes: F,T
Risk Statements: 11-23/24/25-39/23/24/25
Safety Statements: 7-16-36/37-45
RIDADR: UN 1230 3/PG 2
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: L5011
Product name: Leukotriene D4
Purity: ~50?μg/mL (in methanol/ammonium acetate buffer, 70:30, pH 5.6), ≥97%
Packaging: 10μg
Price: $317
Updated: 2024/03/01

Sigma-Aldrich

Product number: L5011
Product name: Leukotriene D4
Purity: ~50?μg/mL (in methanol/ammonium acetate buffer, 70:30, pH 5.6), ≥97%
Packaging: 25μg
Price: $629
Updated: 2024/03/01

Sigma-Aldrich

Product number: L5011
Product name: Leukotriene D4
Purity: ~50?μg/mL (in methanol/ammonium acetate buffer, 70:30, pH 5.6), ≥97%
Packaging: 50μg
Price: $950
Updated: 2024/03/01

Sigma-Aldrich

Product number: L5011
Product name: Leukotriene D4
Purity: ~50?μg/mL (in methanol/ammonium acetate buffer, 70:30, pH 5.6), ≥97%
Packaging: 250μg
Price: $2130
Updated: 2022/05/15

Cayman Chemical

Product number: 20310
Product name: Leukotriene D4
Purity: ≥97%
Packaging: 25μg
Price: $144
Updated: 2024/03/01

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LEUKOTRIENE D4 Chemical Properties,Usage,Production

Description

Leukotriene D₄ (LTD₄) is an active metabolite of LTC₄ (Item Nos. 20210 | 10007241) and a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is formed via metabolism of LTC₄ by γ-glutamyl transpeptidase. Like LTC₄, LTD₄ (0.01-0.1 pM) induces contractions in isolated guinea pig parenchymal strips and tracheal spirals. In vivo, LTD₄ increases insufflation pressure, a marker of bronchoconstriction, in anesthetized guinea pigs by 100% when administered at a dose of 89 pmol per animal. It also increases vascular permeability in guinea pig skin when administered intradermally at a dose of 0.1 pmol per animal.

Uses

LTD4 (Leukotriene D4) is a member of the leukotriene family shown to be a potent contractor of smooth muscle.

Definition

ChEBI: A leukotriene that is (7E,9E,11Z,14Z)-icosa-7,9,11,14-tetraenoic acid substituted by a hydroxy group at position 5 (5S) and a L-cysteinylglycinyl group at position 6 (6R).

Biochem/physiol Actions

Slow reacting substance of anaphylaxis (SRS-A). Potent bronchoconstrictor and mediator of asthmatic and inflammatory processes. Increases cytosolic free Ca2+ in epithelial cells.

LEUKOTRIENE D4 Preparation Products And Raw materials

Raw materials

Preparation Products

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LEUKOTRIENE D4 Suppliers

China 19 Germany 2 India 1 Switzerland 1 United Kingdom 1 United States 8 Global 32

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-400-6206333 18521732826
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4428
Advantage: 55

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11217
Advantage: 58

Guangzhou Younan Technology Co., Ltd

Tel: 020-82000279 18988968278
Fax: QQ：3283937693
Email: sales@ubiochem.com
Country: China
ProdList: 4297
Advantage: 58

Taizhou Nanfeng Pharmaceutical Research Institute

Tel: 18616377689
Email: nanfengdrug@163.com
Country: China
ProdList: 20565
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

73836-78-9, LEUKOTRIENE D4Related Search:

ISOPROPYL N-PROPYL SULFIDE ALLYL ETHYL SULFIDE 2-Pentanethiol ALLYL N-PROPYL SULFIDE 2-Mercapto-3-butanol 1,3,5-UNDECATRIENE 2-[(2-AMINOETHYL)THIO]ETHAN-1-OL CYS-GLY 6-Mercaptohexan-1-ol LEUKOTRIENE B4-3-AMINOPROPYLAMIDE LEUKOTRIENE C4 2-HEPTANETHIOL ETHYL SEC-BUTYL SULFIDE 7-OCTENOIC ACID LEUKOTRIENE D4 Propanamide, 3-mercapto-N-methyl- 2-(butylthio)ethanamine LEUKOTRIENE A3 METHYL ESTER

LEUKOTRIENE D4

(r-(r*,s*-(e,e,z,z)))-inyl)

YEESKJGWJFYOOK-IJHYULJSSA-N

glycine,n-(s-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-l-cyste

leukotriened

leukotriened(sub4)

(5S,6R,7E,9E,11E,14E)-6-[2-amino-2-(carboxymethylcarbamoyl)ethyl]sulfanyl-5-hydroxy-icosa-7,9,11,14-tetraenoic acid

LEUKOTRIENE D4 (ETHANOL SOLUTION)

N-[S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-1-Hydroxy-4-carboxybutyl]-2,4,6,9-pentadecatetraene-1-yl]-L-cysteinyl]glycine

N-[S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-1-Hydroxy-4-carboxybutyl]-2,4,6,9-pentadecatetren-1-yl]-L-cysteinyl]glycine

N-[S-[(1R,2E,4E,6Z,9Z)-1-[(S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetren-1-yl]-L-cysteinyl]glycine

S-[(1R,2E,4E,6Z,9Z)-1-[(S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetren-1-yl]-L-Cys-Gly-OH

LTD4 (Leukotriene D4)

5S-HYDROXY-6R-(S-CYSTEINYLGLYCINYL)-7E,9E,11Z,14Z-EICOSATETRAENOIC ACID

5(S)-HYDROXY-6(R)-S-CYSTEINYLGLYCINYL-7-TRANS-9-TRANS-11-CIS-14-CIS-EICOSATETRAENOIC ACID

LTD4

Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinyl-

Leukotriene D4 (LTD4)

Leukotriene D4 MaxSpecStandard

73836-78-9

BioChemical

Biochemicals and Reagents

Leukotrienes

Lipids

Fatty Acids

Arachidonic Acid Cascade

Fatty Acids

Leukotrienes

LeukotrienesLipids

Lipids in Cell Signaling