ChemicalBook > CAS DataBase List > LEUKOTRIENE D4

LEUKOTRIENE D4

Product Name
LEUKOTRIENE D4
CAS No.
73836-78-9
Chemical Name
LEUKOTRIENE D4
Synonyms
LTD4;leukotriened;LEUKOTRIENE D4;leukotriened(sub4);LTD4 (Leukotriene D4);Leukotriene D4 (LTD4);YEESKJGWJFYOOK-IJHYULJSSA-N;(r-(r*,s*-(e,e,z,z)))-inyl);Leukotriene D4 MaxSpecStandard;LEUKOTRIENE D4 (ETHANOL SOLUTION)
CBNumber
CB1283439
Molecular Formula
C25H40N2O6S
Formula Weight
496.66
MOL File
73836-78-9.mol
More
Less

LEUKOTRIENE D4 Property

Boiling point:
785.8±60.0 °C(Predicted)
Density 
1.162±0.06 g/cm3(Predicted)
Flash point:
9℃
storage temp. 
-70°C
solubility 
A solution in ethanol
form 
Liquid.
pka
3.03±0.10(Predicted)
color 
Colorless to light yellow
More
Less

Safety

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
7-16-36/37-45
RIDADR 
UN 1230 3/PG 2
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L5011
Product name
Leukotriene D4
Purity
~50?μg/mL (in methanol/ammonium acetate buffer, 70:30, pH 5.6), ≥97%
Packaging
10μg
Price
$317
Updated
2024/03/01
Sigma-Aldrich
Product number
L5011
Product name
Leukotriene D4
Purity
~50?μg/mL (in methanol/ammonium acetate buffer, 70:30, pH 5.6), ≥97%
Packaging
25μg
Price
$629
Updated
2024/03/01
Sigma-Aldrich
Product number
L5011
Product name
Leukotriene D4
Purity
~50?μg/mL (in methanol/ammonium acetate buffer, 70:30, pH 5.6), ≥97%
Packaging
50μg
Price
$950
Updated
2024/03/01
Sigma-Aldrich
Product number
L5011
Product name
Leukotriene D4
Purity
~50?μg/mL (in methanol/ammonium acetate buffer, 70:30, pH 5.6), ≥97%
Packaging
250μg
Price
$2130
Updated
2022/05/15
Cayman Chemical
Product number
20310
Product name
Leukotriene D4
Purity
≥97%
Packaging
25μg
Price
$144
Updated
2024/03/01
More
Less

LEUKOTRIENE D4 Chemical Properties,Usage,Production

Description

Leukotriene D4 (LTD4) is an active metabolite of LTC4 (Item Nos. 20210 | 10007241) and a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is formed via metabolism of LTC4 by γ-glutamyl transpeptidase. Like LTC4, LTD4 (0.01-0.1 pM) induces contractions in isolated guinea pig parenchymal strips and tracheal spirals. In vivo, LTD4 increases insufflation pressure, a marker of bronchoconstriction, in anesthetized guinea pigs by 100% when administered at a dose of 89 pmol per animal. It also increases vascular permeability in guinea pig skin when administered intradermally at a dose of 0.1 pmol per animal.

Uses

LTD4 (Leukotriene D4) is a member of the leukotriene family shown to be a potent contractor of smooth muscle.

Definition

ChEBI: A leukotriene that is (7E,9E,11Z,14Z)-icosa-7,9,11,14-tetraenoic acid substituted by a hydroxy group at position 5 (5S) and a L-cysteinylglycinyl group at position 6 (6R).

Biochem/physiol Actions

Slow reacting substance of anaphylaxis (SRS-A). Potent bronchoconstrictor and mediator of asthmatic and inflammatory processes. Increases cytosolic free Ca2+ in epithelial cells.

LEUKOTRIENE D4 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

LEUKOTRIENE D4 Suppliers

China 19 Germany 2 India 1 Switzerland 1 United Kingdom 1 United States 8 Global 32
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4674
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Guangzhou Younan Technology Co., Ltd
Tel
020-82000279 18988968278
Fax
QQ：3283937693
Email
sales@ubiochem.com
Country
China
ProdList
4297
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Shanghai Universal Biotech Co.,Ltd
Tel
13774214275
Email
zhouzz@univ-bio.com
Country
China
ProdList
24994
Advantage
58
Shanghai Yaji Biological Technology Co., Ltd.
Tel
021-34661275 15301693058
Email
yajikit@163.com
Country
China
ProdList
9670
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24644
Advantage
58
Aikon International Limited
Tel
18626450290
Email
yftan@aikonchem.com
Country
China
ProdList
10715
Advantage
58
Shanghai Maclean Biochemical Technology Co., LTD
Tel
021-50706066 15221275939
Email
shenlinxing@macklin.cn
Country
China
ProdList
29902
Advantage
58
Nantong QuanYi Biotechnology Co., Ltd
Tel
0513-66337626 18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
4988
Advantage
58
Taizhou Zhongzhi Biotechnology Co., Ltd
Tel
13012344321
Email
3995296515@qq.com
Country
China
ProdList
7996
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58
Guangzhou WeiBo Chemical Co., Ltd.
Tel
--
Fax
--
Email
weibochem@163.com
Country
China
ProdList
6187
Advantage
67
Advanced Technology & Industrial Co., Ltd.
Tel
--
Fax
--
Email
sales@advtechind.com
Country
China
ProdList
6523
Advantage
75

73836-78-9, LEUKOTRIENE D4Related Search:

ISOPROPYL N-PROPYL SULFIDE ALLYL ETHYL SULFIDE 2-Pentanethiol ALLYL N-PROPYL SULFIDE 2-Mercapto-3-butanol 1,3,5-UNDECATRIENE 2-[(2-AMINOETHYL)THIO]ETHAN-1-OL CYS-GLY 6-Mercaptohexan-1-ol LEUKOTRIENE B4-3-AMINOPROPYLAMIDE LEUKOTRIENE C4 2-HEPTANETHIOL ETHYL SEC-BUTYL SULFIDE 7-OCTENOIC ACID LEUKOTRIENE D4 Propanamide, 3-mercapto-N-methyl- 2-(butylthio)ethanamine LEUKOTRIENE A3 METHYL ESTER

  • LEUKOTRIENE D4
  • (r-(r*,s*-(e,e,z,z)))-inyl)
  • YEESKJGWJFYOOK-IJHYULJSSA-N
  • glycine,n-(s-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-l-cyste
  • leukotriened
  • leukotriened(sub4)
  • (5S,6R,7E,9E,11E,14E)-6-[2-amino-2-(carboxymethylcarbamoyl)ethyl]sulfanyl-5-hydroxy-icosa-7,9,11,14-tetraenoic acid
  • LEUKOTRIENE D4 (ETHANOL SOLUTION)
  • N-[S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-1-Hydroxy-4-carboxybutyl]-2,4,6,9-pentadecatetraene-1-yl]-L-cysteinyl]glycine
  • N-[S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-1-Hydroxy-4-carboxybutyl]-2,4,6,9-pentadecatetren-1-yl]-L-cysteinyl]glycine
  • N-[S-[(1R,2E,4E,6Z,9Z)-1-[(S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetren-1-yl]-L-cysteinyl]glycine
  • S-[(1R,2E,4E,6Z,9Z)-1-[(S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetren-1-yl]-L-Cys-Gly-OH
  • LTD4 (Leukotriene D4)
  • 5S-HYDROXY-6R-(S-CYSTEINYLGLYCINYL)-7E,9E,11Z,14Z-EICOSATETRAENOIC ACID
  • 5(S)-HYDROXY-6(R)-S-CYSTEINYLGLYCINYL-7-TRANS-9-TRANS-11-CIS-14-CIS-EICOSATETRAENOIC ACID
  • LTD4
  • Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinyl-
  • Leukotriene D4 (LTD4)
  • Leukotriene D4 MaxSpecStandard
  • 73836-78-9
  • BioChemical
  • Biochemicals and Reagents
  • Leukotrienes
  • Lipids
  • Fatty Acids
  • Arachidonic Acid Cascade
  • Fatty Acids
  • Leukotrienes
  • LeukotrienesLipids
  • Lipids in Cell Signaling