ChemicalBook > CAS DataBase List > PROSTAGLANDIN D2

PROSTAGLANDIN D2

Product Name
PROSTAGLANDIN D2
CAS No.
41598-07-6
Chemical Name
PROSTAGLANDIN D2
Synonyms
PGDS;PGD2;Prostaglandin D?;PROSTAGLANDIN D2;PROSTAGLANDINS D2;PGD2 (Prostaglandin D2);RP23-47P18.11-006, 21kDa;11-dehydroprostaglandinf2-alpha;Prostaglandin D2 MaxSpecStandard;prostaglandin D2 synthase (brain)
CBNumber
CB2433095
Molecular Formula
C20H32O5
Formula Weight
352.47
MOL File
41598-07-6.mol
More
Less

PROSTAGLANDIN D2 Property

Melting point:
68°C
Boiling point:
406.07°C (rough estimate)
alpha 
+7.5°(D/21℃)(c=1,THF)
Density 
1.0601 (rough estimate)
refractive index 
1.6120 (estimate)
storage temp. 
-20°C
solubility 
Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly), THF (Slightly)
pka
4.76±0.10(Predicted)
form 
White solid
color 
White to Light Orange
BRN 
2170623
Stability:
Light Sensitive
More
Less

Safety

Hazard Codes 
T
Risk Statements 
60-22
Safety Statements 
53-22-26-36
WGK Germany 
3
RTECS 
UK7930000
10
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P308+P313IF exposed or concerned: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P5172
Product name
Prostaglandin D2
Purity
≥95%, synthetic
Packaging
1mg
Price
$200
Updated
2024/03/01
Sigma-Aldrich
Product number
SAB2502046
Product name
Anti-Ptgds antibody produced in goat
Purity
affinity isolated antibody, buffered aqueous solution
Packaging
100μG
Price
$568
Updated
2024/03/01
Sigma-Aldrich
Product number
538909
Product name
Prostaglandin D?
Packaging
1mg
Price
$182
Updated
2024/03/01
Cayman Chemical
Product number
12010
Product name
Prostaglandin D2
Purity
≥98%
Packaging
1mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
12010
Product name
Prostaglandin D2
Purity
≥98%
Packaging
5mg
Price
$216
Updated
2024/03/01
More
Less

PROSTAGLANDIN D2 Chemical Properties,Usage,Production

Description

Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD2 is also produced in the brain via an alternative pathway involving a soluble, secreted PGD-synthase also known as β-trace. In the brain, PGD2 produces normal physiological sleep and lowering of body temperature. Further pharmacological actions include inhibition of platelet aggregation and relaxation of vascular smooth muscle. PGD2 inhibits human ovarian tumor cell proliferation with an IC50 of 6.8 μM.

Uses

Prostaglandin D2 is a fatty acid compound present in the human body. Elevated levels of localized Prostaglandin D2 has been linked to hair loss and growth inhibition. It has also been seen to contribute to the activity of allergic asthma.

Definition

ChEBI: A member of the class of prostaglandins D that is prosta-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9 and 15 and an oxo group at position 11 (the 5Z,9alpha,13E,15S- s ereoisomer).

Biochem/physiol Actions

Primary prostaglandin in brain; induces inflammation; stimulates adenylyl cyclase.

PROSTAGLANDIN D2 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

PROSTAGLANDIN D2 Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185 18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3466
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16684
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Shanghai Synchem Pharma Co., ltd
Tel
21-619849051-1 18521059765
Email
synchempharma@aliyun.com
Country
China
ProdList
6463
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
Advantage
58

41598-07-6, PROSTAGLANDIN D2Related Search:


  • 9,15-dihydroxy-11-oxo-,(5z,9-alpha,13e,15s)-prosta-13-dien-1-oicacid
  • prostaglandin D2 cell culture tested
  • prostaglandind2synthetichygroscopic
  • (5z,9α,13e,15s)-9,15-dihydroxy-11-oxoprosta-5,13-dien-1-oic-acid
  • 7-[(1R,2R,5S)-5-hydroxy-2-[(3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enoic acid
  • PGD2, (5Z,9α,13E,15S)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic-acid
  • (5Z,13E,15S)-9α,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic acid
  • Prostaglandin D2,(5Z,9α,13E,15S)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic-acid, PGD2
  • Prostaglandin D2 Lipid Maps MS Standard
  • (Z)-7-((1R,2R,5S)-5-hydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)-3-oxocyclopentyl)hept-5-enoic acid
  • Anti-Ptgds antibody produced in goat
  • PGDS
  • prostaglandin D2 synthase (brain)
  • RP23-47P18.11-006, 21kDa
  • PGD2 (Prostaglandin D2)
  • Prostaglandin D?
  • PROSTAGLANDIN D2
  • PROSTAGLANDINS D2
  • PGD2
  • 9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID
  • [5Z,9ALPHA,13E,15S]9,15-DIHYDROXY-11-OXOPROSTA-5,13-DIEN-1-OIC ACID
  • 11-dehydroprostaglandinf2-alpha
  • Prostaglandin D2 MaxSpecStandard
  • Prostaglandin D - CAS 41598-07-6 - Calbiochem
  • Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9α,13E,15S)-
  • 41598-07-6
  • Fatty Acids
  • Prostaglandins
  • Lipids
  • BioChemical
  • Biochemicals and Reagents