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PROSTAGLANDIN D2

Product Name
PROSTAGLANDIN D2
CAS No.
41598-07-6
Chemical Name
PROSTAGLANDIN D2
Synonyms
PGDS;PGD2;Prostaglandin D?;PROSTAGLANDIN D2;PROSTAGLANDINS D2;PGD2 (Prostaglandin D2);RP23-47P18.11-006, 21kDa;11-dehydroprostaglandinf2-alpha;Prostaglandin D2 MaxSpecStandard;prostaglandin D2 synthase (brain)
CBNumber
CB2433095
Molecular Formula
C20H32O5
Formula Weight
352.47
MOL File
41598-07-6.mol
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PROSTAGLANDIN D2 Property

Melting point:
68°C
Boiling point:
406.07°C (rough estimate)
alpha 
+7.5°(D/21℃)(c=1,THF)
Density 
1.0601 (rough estimate)
refractive index 
1.6120 (estimate)
storage temp. 
-20°C
solubility 
Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly), THF (Slightly)
pka
4.76±0.10(Predicted)
form 
White solid
color 
White to Light Orange
BRN 
2170623
Stability:
Light Sensitive
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Safety

Hazard Codes 
T
Risk Statements 
60-22
Safety Statements 
53-22-26-36
WGK Germany 
3
RTECS 
UK7930000
F 
10
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P5172
Product name
Prostaglandin D2
Purity
≥95%, synthetic
Packaging
1mg
Price
$200
Updated
2024/03/01
Sigma-Aldrich
Product number
SAB2502046
Product name
Anti-Ptgds antibody produced in goat
Purity
affinity isolated antibody, buffered aqueous solution
Packaging
100μG
Price
$568
Updated
2024/03/01
Sigma-Aldrich
Product number
538909
Product name
Prostaglandin D?
Packaging
1mg
Price
$182
Updated
2024/03/01
Cayman Chemical
Product number
12010
Product name
Prostaglandin D2
Purity
≥98%
Packaging
1mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
12010
Product name
Prostaglandin D2
Purity
≥98%
Packaging
5mg
Price
$216
Updated
2024/03/01
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PROSTAGLANDIN D2 Chemical Properties,Usage,Production

Description

Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD2 is also produced in the brain via an alternative pathway involving a soluble, secreted PGD-synthase also known as β-trace. In the brain, PGD2 produces normal physiological sleep and lowering of body temperature. Further pharmacological actions include inhibition of platelet aggregation and relaxation of vascular smooth muscle. PGD2 inhibits human ovarian tumor cell proliferation with an IC50 of 6.8 μM.

Uses

Prostaglandin D2 is a fatty acid compound present in the human body. Elevated levels of localized Prostaglandin D2 has been linked to hair loss and growth inhibition. It has also been seen to contribute to the activity of allergic asthma.

Definition

ChEBI: A member of the class of prostaglandins D that is prosta-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9 and 15 and an oxo group at position 11 (the 5Z,9alpha,13E,15S- s ereoisomer).

Biochem/physiol Actions

Primary prostaglandin in brain; induces inflammation; stimulates adenylyl cyclase.

PROSTAGLANDIN D2 Preparation Products And Raw materials

Raw materials

Preparation Products

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PROSTAGLANDIN D2 Suppliers

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41598-07-6, PROSTAGLANDIN D2Related Search:

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  • 9,15-dihydroxy-11-oxo-,(5z,9-alpha,13e,15s)-prosta-13-dien-1-oicacid
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  • Prostaglandin D2 Lipid Maps MS Standard
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  • Anti-Ptgds antibody produced in goat
  • PGDS
  • prostaglandin D2 synthase (brain)
  • RP23-47P18.11-006, 21kDa
  • PGD2 (Prostaglandin D2)
  • Prostaglandin D?
  • PROSTAGLANDIN D2
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  • 11-dehydroprostaglandinf2-alpha
  • Prostaglandin D2 MaxSpecStandard
  • Prostaglandin D - CAS 41598-07-6 - Calbiochem
  • Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9α,13E,15S)-
  • 41598-07-6
  • Fatty Acids
  • Prostaglandins
  • Lipids
  • BioChemical
  • Biochemicals and Reagents