PROSTAGLANDIN H1
- Product Name
- PROSTAGLANDIN H1
- CAS No.
- 52589-22-7
- Chemical Name
- PROSTAGLANDIN H1
- Synonyms
- PGH1;PGR1;GPR153;Prostaglandin R1;PROSTAGLANDIN H1;Prostaglandin?H1?(PGH1);NTAYABHEVAQSJS-ZKEWMDECSA-N;G-protein coupled receptor PGR1;Probable G-protein coupled receptor 153;(13E,15S)-9α,11α-Epidioxy-15-hydroxyprost-13-en-1-oic acid
- CBNumber
- CB7166518
- Molecular Formula
- C20H34O5
- Formula Weight
- 354.48
- MOL File
- 52589-22-7.mol
PROSTAGLANDIN H1 Property
- Boiling point:
- 486.2±38.0 °C(Predicted)
- Density
- 1.113±0.06 g/cm3(Predicted)
- Flash point:
- -17 °C
- storage temp.
- −70°C
- solubility
- Ethanol: >100 mg/ml; PBS pH 7.2: >2 mg/ml
- form
- acetone solution
- pka
- 4.78±0.10(Predicted)
Safety
- Hazard Codes
- F,Xi
- Risk Statements
- 11-36-66-67
- Safety Statements
- 9-16-26
- RIDADR
- UN 1090 3/PG 2
- WGK Germany
- 1
N-Bromosuccinimide Price
- Product number
- 17015
- Product name
- Prostaglandin H1
- Purity
- ≥95%
- Packaging
- 25μg
- Price
- $57
- Updated
- 2024/03/01
- Product number
- 17015
- Product name
- Prostaglandin H1
- Purity
- ≥95%
- Packaging
- 50μg
- Price
- $107
- Updated
- 2024/03/01
- Product number
- 17015
- Product name
- Prostaglandin H1
- Purity
- ≥95%
- Packaging
- 100μg
- Price
- $198
- Updated
- 2024/03/01
- Product number
- 17015
- Product name
- Prostaglandin H1
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $874
- Updated
- 2024/03/01
- Product number
- CCH0005999
- Product name
- PROSTAGLANDIN H1
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1683
- Updated
- 2021/12/16
PROSTAGLANDIN H1 Chemical Properties,Usage,Production
Description
Prostaglandin H1 (PGH1) is the unstable precursor to all 1-series PGs and thromboxanes.1,2,3 It is produced from dihomo-γ-linolenic acid (DGLA; Item No. 90230) by COX-1 and COX-2. 4,2 PGH1 is an agonist of the PGD2 receptor CRTH2.5 It increases intracellular calcium levels in HEK293 cells expressing CRTH2 when used at a concentration of 3 µM and induces CRTH2 internalization at 1 µM, an effect that can be blocked by the CRTH2 antagonist TM30089 (CAY10471; Item No. 10006735). PGH1 is also a suicide inhibitor of platelet thromboxane synthase (Ki = 28 µM).6WARNING This product is not for human or veterinary use.
Definition
ChEBI: Prostaglandin H1 is a member of the class of prostaglandins H that is prostaglandin H2 lacking the double bond at position 5. It has a role as a human xenobiotic metabolite. It is a prostaglandins H, an oxylipin, a bridged compound, an olefinic compound, an organic peroxide and a secondary alcohol. It is a conjugate acid of a prostaglandin H1(1-).
PROSTAGLANDIN H1 Preparation Products And Raw materials
Raw materials
Preparation Products
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