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PROSTAGLANDIN F1ALPHA

Product Name
PROSTAGLANDIN F1ALPHA
CAS No.
745-62-0
Chemical Name
PROSTAGLANDIN F1ALPHA
Synonyms
PGF1;PGF1α;C06475;PGF1ALPHA;protaglandinf1;prostaglandinf1;PROSTAGLANDIN F1A;Prostaglandin F1α;PROSTAGLANDIN F1ALPHA;PROSTAGLANDINS F1ALPHA
CBNumber
CB1237881
Molecular Formula
C20H36O5
Formula Weight
356.5
MOL File
745-62-0.mol
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PROSTAGLANDIN F1ALPHA Property

Melting point:
102.5°C
Boiling point:
409.31°C (rough estimate)
alpha 
+24°(D/24℃)(c=0.87,THF)
Density 
1.0321 (rough estimate)
refractive index 
1.6120 (estimate)
storage temp. 
-20°C
solubility 
DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 2 mg/ml
form 
A crystalline solid
pka
4.78±0.10(Predicted)
BRN 
2704846
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
GY4569700
8-10
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
15010
Product name
Prostaglandin F1α
Purity
≥98%
Packaging
1mg
Price
$55
Updated
2024/03/01
Cayman Chemical
Product number
15010
Product name
Prostaglandin F1α
Purity
≥98%
Packaging
5mg
Price
$243
Updated
2024/03/01
Cayman Chemical
Product number
15010
Product name
Prostaglandin F1α
Purity
≥98%
Packaging
10mg
Price
$404
Updated
2024/03/01
Cayman Chemical
Product number
25900
Product name
Prostaglandin F1α MaxSpec? Standard
Purity
>95%
Packaging
100μg
Price
$94
Updated
2023/06/20
TRC
Product number
P294218
Product name
PGF1alpha(ProstaglandinF1alpha)
Packaging
2.5mg
Price
$105
Updated
2021/12/16
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PROSTAGLANDIN F1ALPHA Chemical Properties,Usage,Production

Description

Prostaglandin F (PGF) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF and PGF (Item Nos. 16010 | 10007221) have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10−11 M. PGF binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF. It is only half as active as PGF in inducing human respiratory smooth muscle contractions in vitro.

Description

Prostaglandin F (PGF) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF and PGF (Item Nos. 16010 | 10007221) have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10−11 M. PGF binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF. It is only half as active as PGF in inducing human respiratory smooth muscle contractions in vitro.

PGF MaxSpec® standard is a quantitative grade standard of PGF that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This PGF MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.

Uses

Prostaglandin F1α (PGF1α) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1α and PGF2α have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10?11 M. PGF1α binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2α. It is only half as active as PGF2α in inducing human respiratory smooth muscle contractions in vitro.

Uses

PGF1alpha (Prostaglandin F1alpha) is a smooth muscle relaxant and a stable metabolite of prostacyclin (PGI2).

Definition

ChEBI: Prostaglandin F1alpha is a prostaglandins Falpha. It has a role as a human metabolite.

General Description

Prostaglandins (PGs) contain prostanoic acid. They are divided as PGA, PGB, PGC, PGD, PGE and PGF groups. They all contain a five-member ring structure differing in their functions. PGF is known to be more soluble in phosphate buffer. PGF1α is a serum eicosanoid.

Biochem/physiol Actions

PGs mediate vasodilation and vasoconstriction.

PROSTAGLANDIN F1ALPHA Preparation Products And Raw materials

Raw materials

Preparation Products

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PROSTAGLANDIN F1ALPHA Suppliers

Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd
Tel
0571-85361029
Fax
0571-85361029
Email
synstar518@163.com
Country
China
ProdList
1990
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30241
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Shanghai Universal Biotech Co.,Ltd
Tel
13774214275
Email
gaojun@univ-bio.com
Country
China
ProdList
24990
Advantage
58
QUALITY CONTROL SOLUTIONS LTD.
Tel
0755-66853366; 13670046396
Email
ORDERS@QCSRM.COM
Country
China
ProdList
18882
Advantage
58
amyjetsci
Tel
027-59626688 18771149750
Email
sales@amyjet.com
Country
China
ProdList
3003
Advantage
58

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