ChemicalBook > CAS DataBase List > UNOPROSTONE

UNOPROSTONE

Product Name
UNOPROSTONE
CAS No.
120373-36-6
Chemical Name
UNOPROSTONE
Synonyms
UNOPROSTONE;Unii-6X4F561V3w;Unoprostone [inn];Emorfazone Impurity 6;Alprostadil Impurity 20;Unoprostone(solution in acetate);13,14-DIHYDRO-15-KETO-20-ETHYL PROSTAGLANDIN F2ALPHA;9ALPHA, 11ALPHA-DIHYDROXY-15-OXO-20A,20B-DIHOMOPROST-5-EN-1-OIC ACID;(E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoic acid;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-, (5Z)-
CBNumber
CB7220472
Molecular Formula
C22H38O5
Formula Weight
382.53
MOL File
120373-36-6.mol
More
Less

UNOPROSTONE Property

Boiling point:
562.9±40.0 °C(Predicted)
Density 
1.069±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 25 mg/ml; DMSO: 17 mg/ml; Ethanol: 12 mg/ml; PBS (7.2): 90 μg/ml
form 
Liquid
pka
4.76±0.10(Predicted)
color 
Colorless to light yellow
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
16680
Product name
Unoprostone
Purity
≥98%
Packaging
1mg
Price
$61
Updated
2024/03/01
Cayman Chemical
Product number
16680
Product name
Unoprostone
Purity
≥98%
Packaging
5mg
Price
$264
Updated
2024/03/01
Cayman Chemical
Product number
16680
Product name
Unoprostone
Purity
≥98%
Packaging
10mg
Price
$468
Updated
2024/03/01
Cayman Chemical
Product number
16680
Product name
Unoprostone
Purity
≥98%
Packaging
50mg
Price
$1862
Updated
2024/03/01
TRC
Product number
U847060
Product name
Unoprostane
Packaging
5mg
Price
$210
Updated
2021/12/16
More
Less

UNOPROSTONE Chemical Properties,Usage,Production

Uses

Unoprostane is a protectant against retinal degeneration in S334ter rhodopsin mutant rats. Neuroprotective agent.

Definition

ChEBI: Unoprostone is an oxo monocarboxylic acid, a prostaglandins Falpha and a ketone. It has a role as an antiglaucoma drug and an antihypertensive agent.

General Description

Unoprostone (Rescula) is supplied as a 0.15% sterileophthalmic solution. Unoprostone is somewhat unusual inthat it is a docosanoid (22-carbon atom) PGF2α analog marketedas the isopropyl ester. The natural 15-position alcoholis oxidized to the ketone as would be expected to occur invivo. Cautions and side effects are similar to those givenpreviously.

in vivo

Unoprostone (0.06%, 0.12%; topical instillation; 3 μl) reduces mouse intraocular pressure (IOP) in a dose-dependent manner[3].

Animal Model:Male mice (6 weeks old)[3]
Dosage:0.06%, 0.12%
Administration:Topical instillation; 3 μl
Result:Reduced mouse IOP in a dose-dependent manner.

UNOPROSTONE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

UNOPROSTONE Suppliers

China 34 Europe 1 Germany 1 India 2 South Korea 1 Switzerland 1 United Kingdom 1 United States 9 Global 50
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Alchemist-pharm chemical Technology Co. Ltd.
Tel
0371-67991738 13783628208
Fax
QQ 412703949
Email
carl@alchemist-pharm.com
Country
China
ProdList
1872
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-037163312495,13303845143 13303845143
Fax
QQ3001379618
Email
3001379618@qq.com
Country
China
ProdList
10267
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
Taizhou Crene Biotechnology Co. Ltd.
Tel
+86-0576-88813233 +86-13396860566
Email
sales@pharm-intermediates.com
Country
China
ProdList
1991
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58

120373-36-6, UNOPROSTONERelated Search:

UNOPROSTONE N-ETHYL AMIDE 13,14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA UNOPROSTONE isopropyl unoprostone,UNOPROSTONE ISOPROPYL ESTER cis-5-Eicosenoic acid

  • UNOPROSTONE
  • 9ALPHA, 11ALPHA-DIHYDROXY-15-OXO-20A,20B-DIHOMOPROST-5-EN-1-OIC ACID
  • Unii-6X4F561V3w
  • Unoprostone [inn]
  • 13,14-DIHYDRO-15-KETO-20-ETHYL PROSTAGLANDIN F2ALPHA
  • (E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoic acid
  • 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-, (5Z)-
  • Alprostadil Impurity 20
  • Emorfazone Impurity 6
  • Unoprostone(solution in acetate)
  • 120373-36-6