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11-DEOXY PROSTAGLANDIN F1ALPHA

Product Name
11-DEOXY PROSTAGLANDIN F1ALPHA
CAS No.
37785-98-1
Chemical Name
11-DEOXY PROSTAGLANDIN F1ALPHA
Synonyms
11-deoxy Prostaglandin F1α;HYBPXYQCXNOTFK-DUSCRHDRSA-N;11-DEOXY PROSTAGLANDIN F1ALPHA;9ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC ACID
CBNumber
CB7204575
Molecular Formula
C20H36O4
Formula Weight
340.5
MOL File
37785-98-1.mol
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11-DEOXY PROSTAGLANDIN F1ALPHA Property

storage temp. 
Store at -20°C
solubility 
DMF: >50 mg/ml (from PGF1a); DMSO: >50 mg/ml (from PGF1a); Ethanol: >75 mg/ml (from PGF1a); PBS pH 7.2: >2 mg/ml (from PGF1a)
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
15512
Product name
11-deoxy Prostaglandin F1α
Purity
≥99%
Packaging
1mg
Price
$54
Updated
2024/03/01
Cayman Chemical
Product number
15512
Product name
11-deoxy Prostaglandin F1α
Purity
≥99%
Packaging
5mg
Price
$231
Updated
2024/03/01
Cayman Chemical
Product number
15512
Product name
11-deoxy Prostaglandin F1α
Purity
≥99%
Packaging
10mg
Price
$410
Updated
2024/03/01
AK Scientific
Product number
1152AH
Product name
11-DeoxyprostaglandinF1alpha
Packaging
1mg
Price
$156
Updated
2021/12/16
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11-DEOXY PROSTAGLANDIN F1ALPHA Chemical Properties,Usage,Production

Description

11-deoxy PGF1α is a synthetic analog of PGF1α. In whole animal studies, a dose of 32 mg/kg inhibited gastric acid secretion by 35%. 11-deoxy PGF1α is also known to cause rat uterine contractions at a dose 0.3 times that of PGF1α. It also exhibits vasopressor and bronchoconstrictor activities at about half the potency of PGF2α in guinea pigs.

Uses

11-deoxy Prostaglandin F1α (11-deoxy PGF1α) is an analog of prostaglandin F1α, exhibits side effects on intestines and causes the uterine contraction. 11-deoxy Prostaglandin F1α exhibits activity as vasopressor and bronchoconstrictor[1][2].

Definition

ChEBI: 11-Deoxy-PGF1alpha is a prostanoid.

in vivo

11-deoxy PGF1α (0-10 mg/kg, i.v., single dose) stimulates the uterine contraction in pregnant SD rats, while reveals slightly efficacy on hamster fertility[1].

Animal Model:pregnant Sprague-Dawley rats[1]
Dosage:0-10 mg/kg
Administration:i.v., single dose
Result:Stimulated uterine contraction 3 times active as PGF1α.

References

[1] Broughton BJ, et al., Uterine stimulant action of some omega-chain modified (+)-11-deoxyprostaglandins. Prostaglandins. 1981 Jul;22(1):53-64. DOI:10.1016/0090-6980(81)90053-8
[2] Hall DW, et al., Structure-activity relationships in a series of 11-deoxy prostaglandins. Prostaglandins. 1976 Mar;11(3):573-87. DOI:10.1016/0090-6980(76)90106-4

11-DEOXY PROSTAGLANDIN F1ALPHA Preparation Products And Raw materials

Raw materials

Preparation Products

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11-DEOXY PROSTAGLANDIN F1ALPHA Suppliers

China 9 United States 2 Global 11
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
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China
ProdList
6777
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58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
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58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11973
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58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
29496
Advantage
58
Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
Advantage
58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
Advantage
58
Guangzhou Biopark Technology Co., Ltd.
Tel
020-83808789
Country
CHINA
ProdList
179
Advantage
58

37785-98-1, 11-DEOXY PROSTAGLANDIN F1ALPHARelated Search:

PGG1 6-KETO[5,8,9,11,12,14,15(N)-3H]-PROSTAGLANDIN F1ALPHA 19(R)-HYDROXY PROSTAGLANDIN F1ALPHA PROSTAGLANDIN F1ALPHA 6-KETO PROSTAGLANDIN F1ALPHA-D4 17,20-DIMETHYL PROSTAGLANDIN F1ALPHA 5,6BETA-DIHYDRO PGI2 PROSTAGLANDIN H1 9ALPHA, 15S-DIHYDROXY-11-OXO-PROST-13E-EN-1-OIC-3,3,4,4-D4 ACID 3-METHOXY PROSTAGLANDIN F1ALPHA 6-KETO-PROSTAGLANDIN F1ALPHA 11-DEOXY PROSTAGLANDIN F1ALPHA 9ALPHA,15S-DIHYDROXY-11-OXO-PROST-13E-EN-1-OIC ACID

  • 9ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC ACID
  • HYBPXYQCXNOTFK-DUSCRHDRSA-N
  • 11-DEOXY PROSTAGLANDIN F1ALPHA
  • 11-deoxy Prostaglandin F1α
  • 37785-98-1