13,14-DIHYDROPROSTAGLANDIN E1

Product Name: 13,14-DIHYDROPROSTAGLANDIN E1
CAS No.: 58962-34-8
Chemical Name: 13,14-DIHYDROPROSTAGLANDIN E1
Synonyms: 6-Keto Prostaglandin;6-KETOPROSTAGLANDIN F1A;6-Oxo-prostaglandin F1α;6-oxo-prostaglandin F1alpha;KFGOFTHODYBSGM-ZUNNJUQCSA-N;6-Keto-PGF_1alpha;6-KETO-PROSTAGLANDIN F1ALPHA;6-Keto-Prostaglandin F1-alfa;PROSTAGLANDIN F1-ALPHA, 6-KETO-;Epoprostenol Related CoMpound A
CBNumber: CB1721856
Molecular Formula: C20H34O6
Formula Weight: 370.48
MOL File: 58962-34-8.mol

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13,14-DIHYDROPROSTAGLANDIN E1 Property

Boiling point:: 575.3±50.0 °C(Predicted)
Density: 1.191±0.06 g/cm3(Predicted)
RTECS: UK8428300
storage temp.: −20°C
solubility: ethanol: 10 mg/mL, clear, faintly yellow
pka: 4.69±0.10(Predicted)
form: White to off-white solid.
color: White to off-white
BRN: 2821925

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 8-10
HS Code: 2937909000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1237611
Product name: Epoprostenol Related Compound A
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 15mg
Price: $1350
Updated: 2025/07/31

Cayman Chemical

Product number: 15210
Product name: 6-keto Prostaglandin F1α
Purity: ≥98%
Packaging: 1mg
Price: $97
Updated: 2024/03/01

Cayman Chemical

Product number: 15210
Product name: 6-keto Prostaglandin F1α
Purity: ≥98%
Packaging: 5mg
Price: $360
Updated: 2024/03/01

Cayman Chemical

Product number: 15210
Product name: 6-keto Prostaglandin F1α
Purity: ≥98%
Packaging: 10mg
Price: $672
Updated: 2024/03/01

Cayman Chemical

Product number: 10007219
Product name: 6-keto Prostaglandin F1α MaxSpec? Standard
Purity: ≥95%
Packaging: 100μg
Price: $143
Updated: 2023/06/20

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13,14-DIHYDROPROSTAGLANDIN E1 Chemical Properties,Usage,Production

Description

6-keto prostaglandin F_1α (6-keto PGF_1α) is the inactive, non-enzymatic hydrolysis product of PGI₂. 6-keto PGF_1α serves as a useful marker of PGI₂ biosynthesis in vivo. When [³H]-PGI₂ is injected into healthy human males, 6.6% of the radioactivity is recovered from urine as [³H]-6-keto PGF_1α.

Uses

6-Ketoprostaglandin F1α is the stable hydrolysis product of prostacyclin (P839060), an eicosanoid which prevents the formation of platelet plugs and an effective vasodilator.

Definition

ChEBI: A prostaglandin Falpha that is prostaglandin F1alpha bearing a keto substituent at the 6-position.

IC 50

Human Endogenous Metabolite

References

[1] PACE-ASCIAK C. Isolation, structure, and biosynthesis of 6-ketoprostaglandin F1.alpha. in the rat stomach[J]. Journal of the American Chemical Society, 1976, 98 8: 2348-2349. DOI: 10.1021/ja00424a065
[2] ROY A. JOHNSON. The chemical structure of prostaglandin X (prostacyclin)[J]. Prostaglandins, 1976, 12 6: Pages 915-928. DOI: 10.1016/0090-6980(76)90126-x
[3] A R BRASH. Metabolic disposition of prostacyclin in humans.[J]. Journal of Pharmacology and Experimental Therapeutics, 1983, 226 1: 78-87.
[4] MALARVIZHI GURUSAMY. Inhibition of microsomal prostaglandin E synthase-1 ameliorates acute lung injury in mice.[J]. Journal of Translational Medicine, 2021: 340. DOI: 10.1186/s12967-021-03016-9

13,14-DIHYDROPROSTAGLANDIN E1 Preparation Products And Raw materials

Raw materials

Preparation Products

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13,14-DIHYDROPROSTAGLANDIN E1 Suppliers

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58962-34-8, 13,14-DIHYDROPROSTAGLANDIN E1Related Search:

PROSTAGLANDIN F1-ALPHA, 6-KETO-

6-KETO-PROSTAGLANDIN F1ALPHA

6-OXO-9ALPHA,11ALPHA,15S-TRIHYDROXY-PROST-13E-EN-1-OIC ACID

6-KETOPROSTAGLANDIN F1A

6-keto Prostaglandin F1α Lipid Maps MS Standard

Epoprostenol Related CoMpound A

(9α,11α,13e,15s)-9,11,15-trihydroxy-6-oxoprosta-13-en-1-oic acid

7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]-6-oxoheptanoic acid

6-KETO-PROSTAGLANDIN F1ALPHA EIA STANDARD

6-Oxo-prostaglandin F1α, (9α,11α,13E,15S)-9,11,15-Trihydroxy-6-oxoprosta-13-en-1-oic acid

6-Keto Prostaglandin

6-Oxo-prostaglandin F1α

6-oxo-prostaglandin F1alpha

KFGOFTHODYBSGM-ZUNNJUQCSA-N

6-keto Prostaglandin F1 MaxSpecStandard

(9alpha,11alpha,13E,15S)-9,11,15-Trihydroxy-6-oxoprost-13-en-1-oic acid

6-Keto-PGF<sub>1alpha</sub>

6-Ketoprostaglandin F<sub>1alpha</sub>

6-Keto-Prostaglandin F1-alfa

6-Keto-Prostaglandin F1-alfa-d5

Prost-13-en-1-oic acid, 9,11,15-trihydroxy-6-oxo-, (9α,11α,13E,15S)-

6-keto Prostaglandin F1α MaxSpec? Standard

Epoprostenol Related Compound A (7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(S,E)-3-hydroxyoct-1-enyl]cyclop (1237611)

6-keto Prostaglandin F1α Lipid Maps? MS Standard

58962-34-8

58962-34-2