Misoprostol Acid

Product Name: Misoprostol Acid
CAS No.: 112137-89-0
Chemical Name: Misoprostol Acid
Synonyms: MISOPROSTOL ACID;MISOPROSTOL FREE ACID;8-iso Misoprostol acid;Misoprostol Acid USP/EP/BP;Misoprostol acid,racemic mixture;Misoprostol Acid, Technical Grade 65%;Misoprostol Acid (10 mg in 1 mL Methyl Acetate);(-15-Deoxy-(16RS)-16-hydroxy-16-methylprogestaglandin E;(+-)-15-DEOXY-[16RS]-16-HYDROXY-16-METHYLPROSTAGLANDINE1;(+/-)-15-DEOXY-[16RS]-16-HYDROXY-16-METHYLPROSTAGLANDIN E1
CBNumber: CB0713294
Molecular Formula: C21H36O5
Formula Weight: 368.51
MOL File: 112137-89-0.mol

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Misoprostol Acid Property

Boiling point:: 538.3±50.0 °C(Predicted)
Density: 1.118±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: Chloroform
form: Yellow viscous oil.
pka: 4.77±0.10(Predicted)
color: Pale Yellow
Stability:: Temperature Sensitive

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Safety

Hazard Codes: T
Risk Statements: 45-60-61-25-36/37/38
Safety Statements: 53-22-36/37/39-45-26
RIDADR: UN 2810 6.1/PG 3
WGK Germany: 2
HazardClass: 6.1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M6932
Product name: Misoprostol free acid
Purity: ≥90%
Packaging: 1mg
Price: $188
Updated: 2024/03/01

Alfa Aesar

Product number: J67475
Product name: Misoprostol, free acid
Packaging: 1mg
Price: $85.65
Updated: 2024/03/01

Alfa Aesar

Product number: J67475
Product name: Misoprostol, free acid
Packaging: 5mg
Price: $304
Updated: 2021/12/16

Cayman Chemical

Product number: 13821
Product name: Misoprostol (free acid)
Purity: ≥97%
Packaging: 1mg
Price: $56
Updated: 2024/03/01

Cayman Chemical

Product number: 13821
Product name: Misoprostol (free acid)
Purity: ≥97%
Packaging: 5mg
Price: $249
Updated: 2024/03/01

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Misoprostol Acid Chemical Properties,Usage,Production

Description

Misoprostol is a prostaglandin E₁ analog with agonist activity mediated by EP₂, EP₃, and EP₄ receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED₅₀ = 0.31 μg/kg), inhibit superoxide generation in human neutrophils (EC₅₀ = 0.35 μM), and relax fetal rabbit ductus arteriosus (EC₅₀ = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with mifepristone (RU-486; ) for the oral induction of first trimester abortion. Misoprostol contains a C-1 methyl ester and is readily absorbed and rapidly hydrolyzed in humans to the active free acid.

Chemical Properties

Pale Yellow Gel

Uses

A metabolite of Misoprostol. Cytoprotective PGE1 analog that prevents NSAID-induced gastric ulceration

Uses

A cytoprotective prostaglandin PGE1 analogue.

Uses

Misoprostol Acid is a prostaglandin E1 analog with agonist activity mediated by EP2, EP3, and EP4 receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED50 = 0.31 μg/kg), inhibit superoxide generation in human neutrophils (EC50 = 0.35 μM), and relax fetal rabbit ductus arteriosus (EC50 = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with mifepristone (RU-486; ) for the oral induction of first trimester abortion. Misoprostol contains a C-1 methyl ester and is readily absorbed and rapidly hydrolyzed in humans to the active free acid.

Biochem/physiol Actions

Misoprostol is a synthetic prostaglandin E1 (PGE1) analogue use to prevent non steroidal anti inflammatory drug-induced (NSAID) gastric ulcers; as a labor inducing and postpartum hemorrhage treatment agent.

Misoprostol Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Misoprostol Acid Suppliers

Canada 1 China 28 India 3 Switzerland 1 United Kingdom 3 United States 14 Global 50

J & K SCIENTIFIC LTD.

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Sigma-Aldrich

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BOC Sciences

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Aikon International Limited

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Shanghai Hongye Biotechnology Co. Ltd

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Shenzhen Polymeri Biochemical Technology Co., Ltd.

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112137-89-0, Misoprostol Acid Related Search:

PROSTAGLANDIN D2 PROSTAGLANDIN B1 Fluprostenol Prostaglandin F2a PROSTAGLANDIN F1ALPHA Latanoprost 13,14-DIHYDROPROSTAGLANDIN E1 11BETA-PROSTAGL AND IN F2ALPHA LEUKOTRIENE B4 DIMETHYL AMIDE LEUKOTRIENE D4 L-161,982 6(R)-(4-CARBOXYPHENYLTHIO)-5(S)-HYDROXY-7(E),9(E),11(Z),14(Z)-EICOSATETRAENOIC ACID Misoprostol Acid (+/-)-15-DEOXY-[16RS]-16-HYDROXY-16-METHYLPROSTAGLANDIN E1 Misoprostol acid-d5 MISOPROSTOL Mexiprostil MISOPROSTOL-D4

MISOPROSTOL FREE ACID

(+/-)-15-DEOXY-[16RS]-16-HYDROXY-16-METHYLPROSTAGLANDIN E1

(11a,13E)-11,16-Dihydroxy-16-methyl-9-oxo-prost-13-en-1-oic Acid

(-15-Deoxy-(16RS)-16-hydroxy-16-methylprogestaglandin E

MISOPROSTOL ACID

(+/-)-15-Deoxy-(16RS)-16-hydroxy-16-methylprogestaglandin E1

Misoprostol free acid,(±)-15-Deoxy-(16RS)-16-hydroxy-16-methylprostaglandin E1

Misoprostol Acid (10 mg in 1 mL Methyl Acetate)

Misoprostol Acid, Technical Grade 65% DISCONTINUED. See M368760

Misoprostol Acid, Technical Grade 65%

Misoprostol acid,racemic mixture

Prost-13-en-1-oic acid, 11,16-dihydroxy-16-methyl-9-oxo-, (11α,13E)-

Misoprostol Acid USP/EP/BP

8-iso Misoprostol acid

Misoprostol AcidQ: What is Misoprostol Acid Q: What is the CAS Number of Misoprostol Acid Q: What is the storage condition of Misoprostol Acid Q: What are the applications of Misoprostol Acid

(+-)-15-DEOXY-[16RS]-16-HYDROXY-16-METHYLPROSTAGLANDINE1

Misoprostol, free acid, Saponified analog of prostaglandin E1 methyl ester

112137-89-0

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