4-(Boc-aMino)-3-fluorobenzeneboronic acid pinacol ester

Product Name: 4-(Boc-aMino)-3-fluorobenzeneboronic acid pinacol ester
CAS No.: 262444-42-8
Chemical Name: 4-(Boc-aMino)-3-fluorobenzeneboronic acid pinacol ester
Synonyms: N-Boc-4-amino-3-fluorophenylboronic acid pi;4-(BOC-amino)-3-fluorophenylboronic acid,pinacol;N-Boc-4-amino-3-fluorophenylboronic Acid Pinacol Ester;N-Boc-4-amino-3-fluoro-benzeneboronic acid picol ester;N-Boc-3-fluoro-4-aminophenylboronic acid pinacol ester;4-(BOC-amino)-3-fluorophenyl boronic acid, pinacol ester;N-Boc-4-amino-3-fluoro-benzeneboronic acid pinacol ester;4-(Boc-aMino)-3-fluorobenzeneboronic acid pinacol ester, 96%;N-[2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate;tert-butyl N-[2-fluoro-4-(tetraMethyl-1,3,2- dioxaborolan-2-yl)phenyl]carbaMate
CBNumber: CB2970950
Molecular Formula: C17H25BFNO4
Formula Weight: 337.19
MOL File: 262444-42-8.mol

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4-(Boc-aMino)-3-fluorobenzeneboronic acid pinacol ester Property

Boiling point:: 376.6±37.0 °C(Predicted)
Density: 1.11
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 12.91±0.70(Predicted)
Appearance: White to off-white Solid

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Safety

HS Code: 2931900090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B663118
Product name: 4-(BOC-amino)-3-fluorophenylboronicacid,pinacolester
Packaging: 50mg
Price: $55
Updated: 2021/12/16

Matrix Scientific

Product number: 095416
Product name: tert-Butyl 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylcarbamate
Purity: 95+%
Packaging: 250mg
Price: $152
Updated: 2021/12/16

SynQuest Laboratories

Product number: 8H60-3-30
Product name: tert-Butyl N-[2-fluoro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate
Purity: 97%
Packaging: 250mg
Price: $173
Updated: 2021/12/16

Matrix Scientific

Product number: 095416
Product name: tert-Butyl 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylcarbamate
Purity: 95+%
Packaging: 1g
Price: $336
Updated: 2021/12/16

AK Scientific

Product number: X0663
Product name: 4-(BOC-amino)-3-fluorophenylboronicacidpinacolester
Packaging: 5g
Price: $459
Updated: 2021/12/16

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4-(Boc-aMino)-3-fluorobenzeneboronic acid pinacol ester Chemical Properties,Usage,Production

Synthesis

76-09-5

218301-87-2

262444-42-8

Step 3: 15 g (59 mmol) of (4-((tert-butoxycarbonyl)amino)-3-fluorophenyl)boronic acid obtained from step 2 was reacted with 14 g (118 mmol) of pinacol in methanol for 1 h at room temperature with stirring. The progress of the reaction was monitored by thin layer chromatography (TLC) and after confirming that the reaction was complete, 45 mL of water was added to the reaction mixture and the oily material started to crystallize after grinding. The precipitate was collected by filtration, washed with 70% methanol and dried to give 16 g (48 mmol) of N-Boc-3-fluoro-4-aminophenylboronic acid pinacol ester in 81% yield. The product was characterized by 1H-NMR (DMSO, 300 MHz): δ 9.11 (s, 1H), 7.73 (t, 1H), 7.38 (d, 1H), 7.28 (d, 1H), 1.43 (s, 9H), 1.25 (s, 12H).

References

[1] Patent: EP1878726, 2008, A1. Location in patent: Page/Page column 38
[2] Patent: WO2007/147574, 2007, A1. Location in patent: Page/Page column 56

4-(Boc-aMino)-3-fluorobenzeneboronic acid pinacol ester Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(Boc-aMino)-3-fluorobenzeneboronic acid pinacol ester Suppliers

China 58 Germany 1 India 1 United Kingdom 1 United States 12 Global 73

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262444-42-8, 4-(Boc-aMino)-3-fluorobenzeneboronic acid pinacol esterRelated Search:

4-N-Boc-amino-3-fluorophenylboronic acid (4-BOC-AMINOPHENYL)BORONIC ACID 4-(Boc-aMino)-3-fluorobenzeneboronic acid pinacol ester N-BOC-2-FLUOROANILINE 4-(N-Boc-amino)phenylboronic acid pinacol ester 4-Amino-3-fluorophenylboronic acid, pinacol ester 4-(METHOXYCARBONYLAMINO)BENZENEBORONIC ACID

tert-butyl-2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-ioxaborolan-2-yl)phenylcarbamate

N-Boc-4-amino-3-fluorophenylboronic Acid Pinacol Ester

N-Boc-4-amino-3-fluorophenylboronic acid pi

4-(BOC-amino)-3-fluorophenyl boronic acid, pinacol ester

t-Butyl 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylcarbamate

N-tert-butyl-N-[2-fluoro-4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbaMate

4-(BOC-amino)-3-fluorophenylboronic acid,pinacol

tert-butyl N-[2-fluoro-4-(tetraMethyl-1,3,2- dioxaborolan-2-yl)phenyl]carbaMate

N-[2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate

4-(Boc-aMino)-3-fluorobenzeneboronic acid pinacol ester, 96%

N-Boc-4-amino-3-fluoro-benzeneboronic acid pinacol ester

N-Boc-4-amino-3-fluoro-benzeneboronic acid picol ester

tert-butyl N-[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate

N-[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamic acid tert-butyl ester

Carbamic acid, N-[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-, 1,1-dimethylethyl ester

N-Boc-3-fluoro-4-aminophenylboronic acid pinacol ester

262444-42-8

C17H24BFNO4

C17H25BFNO4