ChemicalBook > CAS DataBase List > 4-(N-Boc-amino)phenylboronic acid pinacol ester

4-(N-Boc-amino)phenylboronic acid pinacol ester

Product Name
4-(N-Boc-amino)phenylboronic acid pinacol ester
CAS No.
330793-01-6
Chemical Name
4-(N-Boc-amino)phenylboronic acid pinacol ester
Synonyms
4-BUT;SKL693;[4-(4,4,5;tert-Butyl-N-[4-(4;2-dioxaborolan-2-yl)phenyl]carbaMate;4-n-boc-phenylboronic acid pinacol ester;tert-Butyl-N-[4-(4,4,5,5-tetramethyl-1,3,2-;4-(Boc-aMino)benzenboronic acid pinacol ester;N-Boc-4-aminophenylboronic acid pinacol ester;4-(tert-Butoxycarbonylamino)benzeneboronicacid
CBNumber
CB3686465
Molecular Formula
C17H26BNO4
Formula Weight
319.2
MOL File
330793-01-6.mol
More
Less

4-(N-Boc-amino)phenylboronic acid pinacol ester Property

Melting point:
167-170 °C(lit.)
Boiling point:
381.1±25.0 °C(Predicted)
Density 
1.07±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Crystalline Powder
pka
14.00±0.70(Predicted)
color 
White to off-white
InChI
InChI=1S/C17H26BNO4/c1-15(2,3)21-14(20)19-13-10-8-12(9-11-13)18-22-16(4,5)17(6,7)23-18/h8-11H,1-7H3,(H,19,20)
InChIKey
HSJNIOYPTSKQBD-UHFFFAOYSA-N
SMILES
C(OC(C)(C)C)(=O)NC1=CC=C(B2OC(C)(C)C(C)(C)O2)C=C1
CAS DataBase Reference
330793-01-6(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22-43
Safety Statements 
37/39-26-36-36/37
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29349990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
562351
Product name
4-(N-Boc-amino)phenylboronic acid pinacol ester
Purity
97%
Packaging
1g
Price
$51.66
Updated
2025/07/31
Sigma-Aldrich
Product number
562351
Product name
4-(N-Boc-amino)phenylboronic acid pinacol ester
Purity
97%
Packaging
5g
Price
$212
Updated
2025/07/31
TCI Chemical
Product number
B5588
Product name
N-(tert-Butoxycarbonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
Purity
>99.0%(HPLC)(T)
Packaging
1g
Price
$40
Updated
2025/07/31
TCI Chemical
Product number
B5588
Product name
N-(tert-Butoxycarbonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
Purity
>99.0%(HPLC)(T)
Packaging
5g
Price
$133
Updated
2025/07/31
Strem Chemicals
Product number
05-0360
Product name
t-Butyl-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate, min. 97%
Packaging
1g
Price
$101
Updated
2024/03/01
More
Less

4-(N-Boc-amino)phenylboronic acid pinacol ester Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Uses

4-(Boc-amino)benzeneboronic acid pinacol ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

73183-34-3

131818-17-2

330793-01-6

Anhydrous dioxane (100 mL) was added to a 250 mL round-bottom flask using pinacol ester of bisboronic acid (10.5 g, 41.5 mmol) and N-tert-butoxycarbonyl-4-bromoaniline (7.75 g, 28.5 mmol). Pd(dppf)Cl2 (0.79 g, 1.1 mmol) and potassium acetate (7.0 g, 71.4 mmol) were subsequently added. The reaction mixture was stirred at 110 °C for 12 h under argon protection. After completion of the reaction, it was cooled to room temperature, filtered and the filtrate was concentrated by rotary evaporator. The residue was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate, 10:1) to afford N-Boc-4-aminophenylboronic acid pinacol ester (3.26 g, 36% yield) as a white solid.1H NMR (400 MHz, DMSO-d6) δ 9.53 (s, 1H), 7.56 (d, J = 8.5 Hz, 2H), 7.47 (d, J = 8.5 Hz, 2H), 1.48 (s, 9H), 1.29 (s, 12H).

References

[1] Dyes and Pigments, 2017, vol. 137, p. 229 - 235
[2] Patent: US2002/156081, 2002, A1
[3] Patent: US6921763, 2005, B2
[4] Tetrahedron Letters, 2014, vol. 55, # 2, p. 305 - 309
[5] MedChemComm, 2014, vol. 5, # 10, p. 1507 - 1514

4-(N-Boc-amino)phenylboronic acid pinacol ester Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-(N-Boc-amino)phenylboronic acid pinacol ester Suppliers

Americas 1 Belgium 1 China 132 Europe 2 France 1 Germany 3 India 6 Japan 2 Switzerland 2 United Kingdom 10 United States 31 Global 191
Hangzhou SuGuan Chemical Technology Co., Ltd.
Tel
15958048562
Fax
-
Email
2032153781@qq.com
Country
China
ProdList
463
Advantage
58
Shanghai Suweike New Materials Co., Ltd
Tel
0512-18896959461 18896959461
Email
efp409@163.com
Country
China
ProdList
500
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
18515581800 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9400
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
More
Less

View Lastest Price from 4-(N-Boc-amino)phenylboronic acid pinacol ester manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
Carbamic acid, N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-, 1,1-dimethylethyl ester 330793-01-6
Price
US $3.00-9.00/KG
Min. Order
0.1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2025-07-03

330793-01-6, 4-(N-Boc-amino)phenylboronic acid pinacol esterRelated Search:

Phenylboronic acid Butyl acetate 3-Aminobenzeneboronic acid Sulfanilic acid Cyhalofop-butyl Aniline Sulfanilamide Methyl acrylate BUTYL OLEATE Tris(trimethylsilyl)phosphate Bis(pinacolato)diboron Dibutyl phthalate PHENYL VALERATE Diethylene glycol monobutyl ether 4-Aminobenzoic acid Dimethyl succinate 4-Aminophenylacetic acid Buprofezin

  • 4-(N-Boc-amino)phenylboronic acid pinacol ester, 97%
  • Carbamic acid, [4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-, 1,1-dimethylethyl ester (9CI)
  • 4-(tert-Butoxycarbonylamino)benzeneboronicacid
  • T-BUTYL-N-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]CARBAMATE
  • T-BUTYL N-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE-2-YL)PHENYL]CARBAMATE
  • T-BUTYL-N-[(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]CARBAMATE
  • TERT-BUTYL-N-[4-(4,4,5,5-TETRAMETHYL-1,2,3-DIOXABOROLAN-2-YL)PHENYL]CARBAMATE
  • TERT-BUTYL-N-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]CARBAMATE
  • TERT-BUTYL-N-METHYL-N-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]CARBAMATE
  • N-BOC-N-METHYL-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ANILINE
  • (4-BOC-N-METHYL-AMINOPHENYL)BORONIC ACID PINACOL ESTER
  • 4-(BOC-AMINO)PHENYLBORONIC ACID PINACOL CYCLIC ESTER
  • (4-BOC-AMINOPHENYL)BORONIC ACID, PINACOL ESTER
  • 4-(BOC-AMINO)BENZENEBORONIC ACID PINACOL ESTER
  • 4-BUTOXYCARBONYLAMINOPHENYLBORONIC ACID, PINACOL ESTER
  • 4-(TERT-BUTOXYCARBONYL-N-METHYLAMINO)PHENYLBORONIC ACID, PINACOL ESTER
  • 4-(TERT-BUTOXYCARBONYLAMINO)PHENYLBORONIC ACID, PINACOL ESTER
  • 4-(T-BUTOXYCARBONYLAMINO)PHENYLBORONIC ACID, PINACOL ESTER
  • 4-(Boc-amino)phenylboronic acid~4-(tert-Butoxycarbonylamino)benzeneboronic acid~4-(tert-Butoxycarbonylamino)phenylboronic acid
  • Carbamic acid, N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-, 1,1-dimethylethyl ester
  • tert-Butyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)
  • N-(tert-Butoxycarbonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
  • 4-BUT
  • 4-n-boc-phenylboronic acid pinacol ester
  • tert-Butyl-N-[4-(4,4,5,5-tetramethyl-1,3,2-
  • tert-Butyl-N-methyl-N-[4-(4,4,5,5-tetramethyl-
  • 4-BUTOXYCARBONYLAMINOPHENYLBORONIC ACID, PINACOL
  • 4-N-Boc-phenylboronic acid pinacol ester, tert-Butyl N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate
  • tert-Butyl-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate, 97+%
  • t-Butyl-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate, min. 97%
  • t-Butyl-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate,min.97%
  • tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylcarbamate
  • 4-Aminobenzeneboronic acid, pinacol ester, N-BOC protected
  • tert-Butyl [4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate, 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline, N-BOC protected
  • 4-(Boc-aMino)benzenboronic acid pinacol ester
  • 2-dioxaborolan-2-yl)phenyl]carbaMate
  • tert-Butyl-N-[4-(4
  • 4-(N-Boc-amino)phenylboronic acid pinacol ester 97%
  • tert-butyl N-[4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbaMate
  • t-Butyl N-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)
  • ert-butylN-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate
  • [4-(4,4,5
  • N-Boc-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
  • SKL693
  • 4-(<i>N</i>-Boc-amino)phenylboronic acid pinacol ester
  • tert-Butyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate - [B1992]
  • N-Boc-4-aminophenylboronic acid pinacol ester
  • N-Boc-4-aminobenzeneboronic acid pinacol ester
  • 4-(N-Boc-amino)phenylboronic acid pinacol ester
  • 330793-01-6
  • C18H28BNO4
  • C11H26BNO4
  • C17H26BNO4
  • Organometallic Reagents
  • Boronate Esters
  • Boronic Acids and Derivatives
  • Aryl
  • organic or inorganic borate