Grb2 Antibody
Source Reactivity Background References- Product Name
- Grb2 Antibody
- Chemical Name
- Grb2 Antibody
- Synonyms
- Grb2 Antibody
- CBNumber
- CB2994848
- Formula Weight
- 0
- MOL File
- Mol file
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N-Bromosuccinimide Price
Biorbyt Ltd
- Product number
- orb18345
- Product name
- GRB2 antibody
- Purity
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Packaging
- 20μg(Trial Size)
- Price
- $127.5
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb378826
- Product name
- GRB2 antibody
- Purity
- Peptide affinity purified
- Packaging
- 100μL
- Price
- $399.5
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb10737
- Product name
- Grb2 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb18345
- Product name
- GRB2 antibody
- Purity
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Packaging
- 100μg
- Price
- $499.8
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb10737
- Product name
- Grb2 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 200μg
- Price
- $673.2
- Updated
- 2021/12/16
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Grb2 Antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human;Mouse;Rat;Hamster;Monkey;Bovine
Background
Growth factor receptor-binding protein 2 is an adaptor protein that is involved in RTK signal transduction. The SH2 domain of GRB2 binds to tyrosine phosphorylated proteins such as EGFR, IRS-1, Shc and Gab1. The SH3 domain of GRB2 associates with Sos, which stimulates the GTP binding activity of Ras, leading to the activation of the MAP kinase and other signaling pathways. Phosphorylation of Tyr209 of GRB2 by Bcr-Abl and EGFR abolishes its association with Sos and negatively regulates downstream signaling.
References
[1] Pawson, T. and Scott, J.D. (1997) Science 278, 2075-80.
[2] Li, S. et al. (2001) EMBO J 20, 6793-804.
Grb2 Antibody Preparation Products And Raw materials
Raw materials
Preparation Products
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Grb2 Antibody Suppliers
- Tel
- 021-38015121 18438616290
- lanwu@univ-bio.com
- Country
- China
- ProdList
- 24731
- Advantage
- 58
- Tel
- 18007124176 19384116026
- 2706668885@qq.com
- Country
- China
- ProdList
- 4987
- Advantage
- 58
- Tel
- 027-19371278702 18008634902
- 19384116026@163.com
- Country
- China
- ProdList
- 3008
- Advantage
- 58
- Tel
- 0755-26755892 1-949-553-1900
- international@genetex.com
- Country
- China
- ProdList
- 6092
- Advantage
- 58
- Tel
- 858.663.9055 8586639055
- NSJBioname@qq.com
- Country
- China
- ProdList
- 6941
- Advantage
- 58
- Tel
- Enzo Biochem Inc. 13797054060
- Enzoname@qq.com
- Country
- China
- ProdList
- 6174
- Advantage
- 58
- Tel
- 18886812933
- sales@biosynth.com
- Country
- China
- ProdList
- 6218
- Advantage
- 58
- Tel
- 21-80243558 86218024
- info@cellsignal.cn
- Country
- China
- ProdList
- 6725
- Advantage
- 58
- Tel
- 4006-123-828 13162017139
- market@ab-mart.com
- Country
- China
- ProdList
- 6917
- Advantage
- 58
- Tel
- 025-58868422
- info@sabbiotech.com
- Country
- China
- ProdList
- 6243
- Advantage
- 58
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Grb2 Antibody