Nestoron

ChemicalBook > CAS DataBase List > Nestoron

Product Name: Nestoron
CAS No.: 7759-35-5
Chemical Name: Nestoron
Synonyms: ST 1435;NESTORON;NESTORONE;Elcometrine;Nestorone Acetate;Nestoron (ST-1435);Norgestone acetate;Segesterone Acetate;ELCOMETRINE;NESTORONE;ST-1435;ST1435;ELCOMETRINE; NESTORONE; ST-1435; ST 1435; ST1435
CBNumber: CB31011778
Molecular Formula: C23H30O4
Formula Weight: 370.48
MOL File: 7759-35-5.mol

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Nestoron Property

Melting point:: 178-179°
alpha: D21 -105° (c = 1.2 in chloroform)
Boiling point:: 420.37°C (rough estimate)
Density: 1.0550 (rough estimate)
refractive index: 1.4433 (estimate)
storage temp.: 2-8°C
solubility: DMSO: soluble5mg/mL, clear
form: powder
color: white to beige
InChIKey: CKFBRGLGTWAVLG-GOMYTPFNSA-N

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H351Suspected of causing cancer

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0550
Product name: Nestorone
Purity: ≥97% (HPLC)
Packaging: 10mg
Price: $96.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0550
Product name: Nestorone
Purity: ≥97% (HPLC)
Packaging: 50mg
Price: $372
Updated: 2024/03/01

Cayman Chemical

Product number: 26441
Product name: Segesterone Acetate
Packaging: 10mg
Price: $78
Updated: 2024/03/01

Cayman Chemical

Product number: 26441
Product name: Segesterone Acetate
Packaging: 25mg
Price: $183
Updated: 2024/03/01

Cayman Chemical

Product number: 26441
Product name: Segesterone Acetate
Packaging: 5mg
Price: $44
Updated: 2024/03/01

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Nestoron Chemical Properties,Usage,Production

Uses

Segesterone Acetate has been used to study the: comparison of androgenic and estrogenic properties of progestins used in contraception and hormone therapy; impact on hepatic estrogen-sensitive proteins by 1-yr contraceptive vaginal ring delivering Nestorone and ethinyl estradiol.

Definition

ChEBI: Elcometrine is a corticosteroid hormone.

Pharmacokinetics

Elcometrine is a member of the 19-norprogesterone class of pr ogestins. when administered subcuta neously (implant), intravaginally (vaginal ring), or transdermally, elcometrine is an exceptionally potent progestin. It is 100-fold more potent when administered subcutaneously than when delivered orally. Its oral bioavaiability is only 10%，with a half life of just 1 to 2 hours because of rapid metabolism. The C16 methylene functionality substantially increases its affinity for the progesterone receptor.

Clinical Use

Because of its antiestrogenic action, elcometrine also can be administered transdermally along with estradiol as a treatment for menopausal symptoms .

Nestoron Preparation Products And Raw materials

Raw materials

Preparation Products

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Nestoron Suppliers

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View Lastest Price from Nestoron manufacturers

Career Henan Chemical Co

Product: Nestoron 7759-35-5
Price: US $1.00/KG
Min. Order: 1G
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-20

7759-35-5, NestoronRelated Search:

Diethylstilbestrol Testosterone undecanoate Medroxyprogesterone Acetate Methylene Blue Megestrol acetate Ethyl acetate Sodium acetate Hydroxyprogesterone acetate 4,4'-Diphenylmethane diisocyanate Norgesterone Cyproterone acetate Methylene Chloride ACETATE 17a-Hydroxy-19-norpregn-4-ene-3,20-dione Gestonoronacetat Nestoron CI NO 50205

ST 1435

NESTORONE

NESTORON

17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate

Elcometrine

17-(ACETYLOXY)-16-METHYLENE-19-NORPREGN-4-ENE-20-DIONE

16-Methylene-17-hydroxy-19-norpregn-4-ene-3,20-dione acetate

16-Methylene-17-alpha-acetoxy-19-nor-4-pregnene-3,20-dione

19-Norpregn-4-ene-3,20-dione, 17-(acetyloxy)-16-methylene- (9ci)

19-Norpregn-4-ene-3,20-dione, 17-hydroxy-16-methylene-, acetate

Nestoron (ST-1435)

17-(Acetyloxy)-16-methylene-19-norpregn-4-ene-3,20-dione

ELCOMETRINE;NESTORONE;ST-1435;ST1435

Segesterone Acetate

(8R,9S,10R,13S,14S,17R)-17-acetyl-13-methyl-16-methylene-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate

ELCOMETRINE; NESTORONE; ST-1435; ST 1435; ST1435

19-Norpregn-4-ene-3,20-dione, 17-(acetyloxy)-16-methylene-

Estr-4-en-3-one,17-acetyl-17-(acetyloxy)-16-methylene-,(17α)-

Norgestone acetate

ST 1435,Inhibitor,Nestoron,ST1435,inhibit,Progesterone Receptor,NR3C3

Nestorone Acetate

7759-35-5

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