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Pyrido[3,4-d]pyrimidin-4(3H)-one (8CI,9CI)

Product Name
Pyrido[3,4-d]pyrimidin-4(3H)-one (8CI,9CI)
CAS No.
19178-25-7
Chemical Name
Pyrido[3,4-d]pyrimidin-4(3H)-one (8CI,9CI)
Synonyms
Pyrido[3.4-d]pyrimidin-4-ol;Pyrido[3,4-d]pyrimidin-4(3H);Pyrido[3,4-d]pyriMidin-4-one;1H-pyrido[3,4-d]pyrimidin-4-one;3H-Pyrido[3,4-d]pyrimidin-4-one;Pyrido[3,4-d]pyriMidin-4(3H)-one;3H,4H-Pyrido[3,4-d]pyrimidin-4-one;3,4-Dihydropyrido[3,4-d]pyrimidin-4-one;3,4-Dihydropyrido[3,4-D]pyrimidine-4-one;Pyrido[3,4-d]pyrimidin-4(3H)-one (8CI,9CI)
CBNumber
CB31045078
Molecular Formula
C7H5N3O
Formula Weight
147.13
MOL File
19178-25-7.mol
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Pyrido[3,4-d]pyrimidin-4(3H)-one (8CI,9CI) Property

Melting point:
305℃
Boiling point:
346.2±34.0 °C(Predicted)
Density 
1.47±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
2.95±0.20(Predicted)
Appearance
Light brown to gray Solid
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

TRC
Product number
P841018
Product name
Pyrido[3,4-d]pyrimidin-4(3H)-one
Packaging
100mg
Price
$65
Updated
2021/12/16
ChemScene
Product number
CS-0046977
Product name
Pyrido[3,4-d]pyrimidin-4(3H)-one
Packaging
250mg
Price
$70
Updated
2021/12/16
ChemScene
Product number
CS-0046977
Product name
Pyrido[3,4-d]pyrimidin-4(3H)-one
Packaging
100mg
Price
$52
Updated
2021/12/16
ChemScene
Product number
CS-0046977
Product name
Pyrido[3,4-d]pyrimidin-4(3H)-one
Packaging
1g
Price
$168
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD144237
Product name
3,4-Dihydropyrido[3,4-d]pyrimidin-4-one
Packaging
250mg
Price
$170
Updated
2021/12/16
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Pyrido[3,4-d]pyrimidin-4(3H)-one (8CI,9CI) Chemical Properties,Usage,Production

Synthesis

3473-63-0

7579-20-6

19178-25-7

3-Aminoisonicotinic acid (691 mg, 5.0 mmol), formamidine acetate (573 mg, 5.5 mmol) and anhydrous ethanol (10 mL) were added to a Biotage microwave reactor tube. The reaction mixture was placed in a microwave reactor and heated at 160 °C for 30 min. After completion of the reaction, the reaction solution was diluted with deionized water (20 mL) and cooled to 0 °C in an ice bath. The resulting suspension was extracted and the filter cake was washed with ice-cooled deionized water (10 mL) to afford quinazoline A2 (259 mg, 35% yield) in white solid form. The product was analyzed by LC-MS showing purity >98% (m/z = 148.0 [M + H]+, retention time Rt = 0.604 min).

References

[1] Journal of Medicinal Chemistry, 2016, vol. 59, # 4, p. 1370 - 1387
[2] Patent: WO2014/179237, 2014, A1. Location in patent: Paragraph 00491

Pyrido[3,4-d]pyrimidin-4(3H)-one (8CI,9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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Pyrido[3,4-d]pyrimidin-4(3H)-one (8CI,9CI) Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
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View Lastest Price from Pyrido[3,4-d]pyrimidin-4(3H)-one (8CI,9CI) manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Pyrido[3,4-d]pyrimidin-4(3H)-one (8CI,9CI) 19178-25-7
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-13