ChemicalBook > CAS DataBase List > Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI)

Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI)

Product Name
Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
CAS No.
220731-04-4
Chemical Name
Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
Synonyms
N2-Boc-pyridine-2,5-diamine;tert-Butyl (5-aminopyridin-2-yl);tert-butyl 5-aminopyridin-2-ylcarbamate;ert-butylN-(5-aminopyridin-2-yl)carbamate;tert-Butyl N-(5-aminopyridin-2-yl)carbamate;Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester;Carbamic acid, N-(5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester;Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
CBNumber
CB31064815
Molecular Formula
C10H15N3O2
Formula Weight
209.24
MOL File
220731-04-4.mol
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Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI) Property

Boiling point:
330.2±27.0 °C(Predicted)
Density 
1.202±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
12.19±0.70(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1S/C10H15N3O2/c1-10(2,3)15-9(14)13-8-5-4-7(11)6-12-8/h4-6H,11H2,1-3H3,(H,12,13,14)
InChIKey
NHVPESPHUUFULF-UHFFFAOYSA-N
SMILES
C(OC(C)(C)C)(=O)NC1=NC=C(N)C=C1
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Safety

Risk Statements 
43
Safety Statements 
36/37
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B750878
Product name
tert-butyl(5-aminopyridin-2-yl)carbamate
Packaging
50mg
Price
$65
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA54514
Product name
(5-Aminopyridin-2-yl)-carbamic acid tert-butyl ester
Packaging
50mg
Price
$63
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA54514
Product name
(5-Aminopyridin-2-yl)-carbamic acid tert-butyl ester
Packaging
100mg
Price
$101
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA54514
Product name
(5-Aminopyridin-2-yl)-carbamic acid tert-butyl ester
Packaging
250mg
Price
$122.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA54514
Product name
(5-Aminopyridin-2-yl)-carbamic acid tert-butyl ester
Packaging
500mg
Price
$225
Updated
2021/12/16
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Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI) Chemical Properties,Usage,Production

Synthesis

161117-88-0

220731-04-4

General procedure for the synthesis of tert-butyl (5-aminopyridin-2-yl)carbamate from tert-butyl (5-nitropyridin-2-yl)carbamate: tert-butyl (5-nitropyridin-2-yl)carbamate (1 eq.), 10% palladium carbon by weight of the raw material and ethyl acetate were added to a reaction flask under hydrogen atmosphere. The reaction mixture was stirred and reacted at room temperature overnight. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and the filtrate was concentrated under reduced pressure to give the target product tert-butyl (5-aminopyridin-2-yl)carbamate. The product was analyzed by HPLC-MS (Method A): retention time Rt = 1.50 min, molecular ion peak [M + H]+ m/z: 210. The reaction yield was quantitative.

References

[1] Patent: WO2016/120808, 2016, A1. Location in patent: Page/Page column 104
[2] Patent: US2010/249099, 2010, A1. Location in patent: Page/Page column 96
[3] Patent: US2011/9405, 2011, A1. Location in patent: Page/Page column 54
[4] Patent: EP2518071, 2012, A1. Location in patent: Page/Page column 41-42
[5] Patent: WO2012/146667, 2012, A1. Location in patent: Page/Page column 95-96

Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI) Suppliers

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View Lastest Price from Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI) manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd
Product
tert-Butyl (5-aminopyridin-2-yl)carbamate 220731-04-4
Price
US $14.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2021-09-25
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
tert-butyl N-(5-aminopyridin-2-yl)carbamate 220731-04-4
Price
US $14.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2021-09-25
Career Henan Chemical Co
Product
Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI) 220731-04-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kgs
Release date
2020-01-29

220731-04-4, Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI)Related Search:

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