Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
- Product Name
- Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
- CAS No.
- 220731-04-4
- Chemical Name
- Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
- Synonyms
- N2-Boc-pyridine-2,5-diamine;tert-Butyl (5-aminopyridin-2-yl);tert-butyl 5-aminopyridin-2-ylcarbamate;ert-butylN-(5-aminopyridin-2-yl)carbamate;tert-Butyl N-(5-aminopyridin-2-yl)carbamate;Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester;Carbamic acid, N-(5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester;Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
- CBNumber
- CB31064815
- Molecular Formula
- C10H15N3O2
- Formula Weight
- 209.24
- MOL File
- 220731-04-4.mol
Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI) Property
- Boiling point:
- 330.2±27.0 °C(Predicted)
- Density
- 1.202±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 12.19±0.70(Predicted)
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C10H15N3O2/c1-10(2,3)15-9(14)13-8-5-4-7(11)6-12-8/h4-6H,11H2,1-3H3,(H,12,13,14)
- InChIKey
- NHVPESPHUUFULF-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)NC1=NC=C(N)C=C1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B750878
- Product name
- tert-butyl(5-aminopyridin-2-yl)carbamate
- Packaging
- 50mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FA54514
- Product name
- (5-Aminopyridin-2-yl)-carbamic acid tert-butyl ester
- Packaging
- 50mg
- Price
- $63
- Updated
- 2021/12/16
- Product number
- FA54514
- Product name
- (5-Aminopyridin-2-yl)-carbamic acid tert-butyl ester
- Packaging
- 100mg
- Price
- $101
- Updated
- 2021/12/16
- Product number
- FA54514
- Product name
- (5-Aminopyridin-2-yl)-carbamic acid tert-butyl ester
- Packaging
- 250mg
- Price
- $122.5
- Updated
- 2021/12/16
- Product number
- FA54514
- Product name
- (5-Aminopyridin-2-yl)-carbamic acid tert-butyl ester
- Packaging
- 500mg
- Price
- $225
- Updated
- 2021/12/16
Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI) Chemical Properties,Usage,Production
Synthesis
161117-88-0
220731-04-4
General procedure for the synthesis of tert-butyl (5-aminopyridin-2-yl)carbamate from tert-butyl (5-nitropyridin-2-yl)carbamate: tert-butyl (5-nitropyridin-2-yl)carbamate (1 eq.), 10% palladium carbon by weight of the raw material and ethyl acetate were added to a reaction flask under hydrogen atmosphere. The reaction mixture was stirred and reacted at room temperature overnight. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and the filtrate was concentrated under reduced pressure to give the target product tert-butyl (5-aminopyridin-2-yl)carbamate. The product was analyzed by HPLC-MS (Method A): retention time Rt = 1.50 min, molecular ion peak [M + H]+ m/z: 210. The reaction yield was quantitative.
References
[1] Patent: WO2016/120808, 2016, A1. Location in patent: Page/Page column 104
[2] Patent: US2010/249099, 2010, A1. Location in patent: Page/Page column 96
[3] Patent: US2011/9405, 2011, A1. Location in patent: Page/Page column 54
[4] Patent: EP2518071, 2012, A1. Location in patent: Page/Page column 41-42
[5] Patent: WO2012/146667, 2012, A1. Location in patent: Page/Page column 95-96
Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI) Suppliers
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- India
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View Lastest Price from Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI) manufacturers
- Product
- tert-Butyl (5-aminopyridin-2-yl)carbamate 220731-04-4
- Price
- US $14.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2021-09-25
- Product
- tert-butyl N-(5-aminopyridin-2-yl)carbamate 220731-04-4
- Price
- US $14.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2021-09-25
- Product
- Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI) 220731-04-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kgs
- Release date
- 2020-01-29