ChemicalBook > CAS DataBase List > Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI)

Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI)

Product Name: Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI)
CAS No.: 71257-38-0
Chemical Name: Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI)
Synonyms: Albb-009270;1H,2H,3H,4H-pyrrolo[1,2-a]pyrazine;pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro-;Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI);1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE 2-BUTENEDIOATE;1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine(SALTDATA: FREE)
CBNumber: CB31066253
Molecular Formula: C7H10N2
Formula Weight: 122.17
MOL File: 71257-38-0.mol

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Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI) Property

Boiling point:: 239.6±28.0 °C(Predicted)
Density: 1.18±0.1 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
pka: 7.40±0.20(Predicted)
Appearance: Colorless to light yellow Liquid

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Safety

RIDADR: 3265
HazardClass: IRRITANT
PackingGroup: Ⅲ
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: T205558
Product name: 1,2,3,4-Tetrahydropyrrolo[1,2-A]pyrazine
Packaging: 50mg
Price: $155
Updated: 2021/12/16

Matrix Scientific

Product number: 027102
Product name: 1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazine
Packaging: 500mg
Price: $145
Updated: 2021/12/16

Apolloscientific

Product number: OR914166
Product name: 1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazine
Purity: 95%
Packaging: 250mg
Price: $170
Updated: 2021/12/16

Matrix Scientific

Product number: 027102
Product name: 1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazine
Packaging: 1g
Price: $223
Updated: 2021/12/16

AK Scientific

Product number: 1057AC
Product name: 1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazine
Packaging: 500mg
Price: $245
Updated: 2021/12/16

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Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI) Chemical Properties,Usage,Production

Synthesis

29709-35-1

50-00-0

71257-38-0

General procedure for the synthesis of 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine from 2-(1H-pyrrol-1-yl)ethylamine and formaldehyde: 2-(1H-pyrrol-1-yl)ethylamine (2 g, 18 mmol) was dissolved in 40 mL of ethanol, followed by the addition of 40% aqueous formaldehyde (1.5 mL, 18 mmol) and the slow dropwise addition of 1 mL trifluoroacetic acid. The reaction mixture was heated to 50 °C and maintained for 15 minutes, then cooled to room temperature and stirred continuously for 12 hours. Upon completion of the reaction, the solvent was removed by concentration under reduced pressure, diluted by adding 50 mL of ethyl acetate, and the organic phase was washed with 50 mL of saturated sodium bicarbonate solution, followed by drying with anhydrous sodium sulfate and filtration. Finally, the filtrate was concentrated by decompression to afford 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine (1.60 g, 72.7% yield) as a light yellow oil.

References

[1] Patent: EP2604610, 2013, A1. Location in patent: Paragraph 0082; 0084
[2] Patent: US2013/131068, 2013, A1. Location in patent: Paragraph 0105
[3] Patent: US2008/153843, 2008, A1. Location in patent: Page/Page column 75
[4] Patent: CN108250128, 2018, A. Location in patent: Paragraph 0787; 0789; 0792; 0793
[5] Patent: US2009/186899, 2009, A1. Location in patent: Page/Page column 37; 41

Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI) manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI) 71257-38-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI) 71257-38-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI) 71257-38-0
Price: US $9.80/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2020-01-10

71257-38-0, Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI)Related Search:

1-METHYL-1,2,3,4-TETRAHYDRO-PYRROLO[1,2-A]PYRAZINE 2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Metralindole 2,3,3A,4,5,6-HEXAHYDRO-8-CYCLOHEXYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE 1-benzyl-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine 2-CHLORO-1-(8-METHYL-1,2,3A,4,5,6-HEXAHYDRO-PYRAZINO[3,2,1-JK]CARBAZOL-3-YL)-ETHANONE 1-(4-METHOXY-PHENYL)-1,2,3,4-TETRAHYDRO-PYRROLO[1,2-A]PYRAZINE 1-(4-CHLOROPHENYL)-1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE 1-PROPYL-1,2,3,4-TETRAHYDRO-PYRROLO[1,2-A]-PYRAZINE Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI) 1-(4-FLUORO-PHENYL)-1,2,3,4-TETRAHYDRO-PYRROLO[1,2-A]PYRAZINE tert-butyl2-(piperazin-1-yl)ethylcarbamate 2,3,3A,4,5,6-HEXAHYDRO-1H-PYRAZINO-[3,2,1-JK]CARBAZOLE 10-CYCLOHEXYL-1,2,3,3A,4,5-HEXAHYDRO-6H-PYRAZINO[1,2,3-L,M]CARBAZOLE 8-METHYL-1,2,3A,4,5,6-HEXAHYDRO-3H-PYRAZINO[3,2,1-JK]CARBAZOLE-3-CARBALDEHYDE 3-BENZYL-2,3,3A,4,5,6-HEXAHYDRO-1H-PYRAZINO[3,2,1-JK]CARBAZOLE-8-CARBALDEHYDE 3-(8-METHYL-1,2,3A,4,5,6-HEXAHYDRO-PYRAZINO-[3,2,1-JK]CARBAZOL-3-YL)PROPIONIC ACID

Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI)

pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro-

Albb-009270

1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine(SALTDATA: FREE)

1H,2H,3H,4H-pyrrolo[1,2-a]pyrazine

1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE 2-BUTENEDIOATE

71257-38-0

AMINETERTIARY