(5-chloro-1H-benzo[d]imidazol-2-yl)methanol
- Product Name
- (5-chloro-1H-benzo[d]imidazol-2-yl)methanol
- CAS No.
- 6953-65-7
- Chemical Name
- (5-chloro-1H-benzo[d]imidazol-2-yl)methanol
- Synonyms
- 2-Benzimidazolemethanol, 5-chloro-;(6-Chloro-1H-benzo[d]imidazol-2-yl);6-Chloro-1H-Benzimidazole-2-methanol;5-Chloro-2-hydroxymethylbenzimidazole;Benzimidazole, 5-chloro-2-hydroxymethyl-;1H-Benzimidazole-2-methanol,5-chloro-(9CI);(5-chloro-1H-benzo[d]imidazol-2-yl)methanol;(6-Chloro-1H-benzo[d]iMidazol-2-yl)Methanol;(5-chloro-1H-benzimidazol-2-yl)methanol(SALTDATA: 0.06NH4Cl)
- CBNumber
- CB31075077
- Molecular Formula
- C8H7ClN2O
- Formula Weight
- 182.61
- MOL File
- 6953-65-7.mol
(5-chloro-1H-benzo[d]imidazol-2-yl)methanol Property
- Melting point:
- 205 °C
- Boiling point:
- 443.9±25.0 °C(Predicted)
- Density
- 1.510±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 10.17±0.10(Predicted)
- Appearance
- Light brown to brown Solid
Safety
- WGK Germany
- 3
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CBR01079
- Product name
- (5-Chloro-1H-benzimidazol-2-yl)methanol
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $81.6
- Updated
- 2023/01/07
- Product number
- C381558
- Product name
- (5-Chloro-1H-benzimidazol-2-yl)methanol
- Packaging
- 500mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- FC120066
- Product name
- (6-Chloro-1H-benzimidazol-2-yl)methanol
- Packaging
- 1g
- Price
- $255
- Updated
- 2021/12/16
- Product number
- OR918810
- Product name
- (5-Chloro-1H-benzimidazol-2-yl)methanol
- Purity
- 95%
- Packaging
- 1g
- Price
- $315
- Updated
- 2021/12/16
- Product number
- FC120066
- Product name
- (6-Chloro-1H-benzimidazol-2-yl)methanol
- Packaging
- 2g
- Price
- $434
- Updated
- 2021/12/16
(5-chloro-1H-benzo[d]imidazol-2-yl)methanol Chemical Properties,Usage,Production
Synthesis
79-14-1
95-83-0
6953-65-7
a) A mixture of 4-chloro-1,2-benzenediamine (105 g, 736 mmol, 1 eq.) and ethanoic acid (112 g, 2 eq.) in xylene (1500 mL) was stirred and refluxed at 150 °C for 4 h. The reaction was carried out with the addition of 3N hydrochloric acid (480 mL). Upon completion of the reaction, the reaction solution was cooled to 60 °C and acidified by slow addition of 3N hydrochloric acid (480 mL), followed by adjusting the pH with ammonia to 7-8. The reaction mixture was filtered and the solid product was collected and washed with water and tert-butyl methyl ether sequentially to afford 123 g of (6-chloro-1H-benzimidazol-2-yl)methanol in 82% yield.
References
[1] Molecules, 2015, vol. 20, # 8, p. 15206 - 15223
[2] Patent: WO2014/60411, 2014, A1. Location in patent: Page/Page column 58
[3] Patent: WO2015/158653, 2015, A1. Location in patent: Page/Page column 37; 38
[4] Annales Pharmaceutiques Francaises, 2003, vol. 61, # 1, p. 57 - 61
[5] Bulletin of the Korean Chemical Society, 2013, vol. 34, # 4, p. 1272 - 1274
(5-chloro-1H-benzo[d]imidazol-2-yl)methanol Preparation Products And Raw materials
Raw materials
Preparation Products
(5-chloro-1H-benzo[d]imidazol-2-yl)methanol Suppliers
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