2(1H)-Pyrimidinone, hydrazone (9CI)
- Product Name
- 2(1H)-Pyrimidinone, hydrazone (9CI)
- CAS No.
- 7504-94-1
- Chemical Name
- 2(1H)-Pyrimidinone, hydrazone (9CI)
- Synonyms
- 2-HydrazinylpyriMidine;2-Pyrimidinylhydrazine;Pyrimidine, 2-hydrazinyl-;1-(2-Pyrimidinyl)hydrazine;2(1H)-Pyrimidinone hydrazone;1-(Pyrimidine-2-yl)hydrazine;2-Hydrazono-2,3-dihydropyrimidine;2(1H)-Pyrimidinone, hydrazone (9CI);2-hydrazinopyrimidine(SALTDATA: FREE);2(1H)-Pyrimidinone, hydrazone (9CI) ISO 9001：2015 REACH
- CBNumber
- CB31081108
- Molecular Formula
- C4H6N4
- Formula Weight
- 110.12
- MOL File
- 7504-94-1.mol
2(1H)-Pyrimidinone, hydrazone (9CI) Property
- Melting point:
- 86-88 °C(Solv: benzene (71-43-2))
- Boiling point:
- 246.3±23.0 °C(Predicted)
- Density
- 1.39±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- form
- solid
- pka
- 6.17±0.20(Predicted)
- color
- Off-white
- InChI
- InChI=1S/C4H6N4/c5-8-4-6-2-1-3-7-4/h1-3H,5H2,(H,6,7,8)
- InChIKey
- QDGHXQFTWKRQTG-UHFFFAOYSA-N
- SMILES
- C1(NN)=NC=CC=N1
- CAS DataBase Reference
- 7504-94-1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- 758094
- Product name
- 2-Hydrazinopyrimidine hydrate
- Purity
- 95%
- Packaging
- 500MG
- Price
- $143
- Updated
- 2023/06/20
- Product number
- H1906
- Product name
- 2-Hydrazinopyrimidine
- Purity
- min. 95.0 %
- Packaging
- 1G
- Price
- $40
- Updated
- 2025/07/31
- Product number
- H1906
- Product name
- 2-Hydrazinopyrimidine
- Purity
- min. 95.0 %
- Packaging
- 5G
- Price
- $120
- Updated
- 2025/07/31
- Product number
- H714413
- Product name
- 2-Hydrazinopyrimidine
- Packaging
- 500mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- AK-81374
- Product name
- 2-Hydrazinylpyrimidine
- Purity
- 97%
- Packaging
- 5g
- Price
- $75
- Updated
- 2021/12/16
2(1H)-Pyrimidinone, hydrazone (9CI) Chemical Properties,Usage,Production
Uses
2-Hydrazinopyrimidine and other pyrimidinylhydrazones have been used to study the fungicidal activity of heteroaromatic aldehyde and ketone pyrimidinylhydrazones.
Synthesis
1722-12-9
7504-94-1
The general procedure for the synthesis of 2-hydrazinopyrimidine from 2-chloropyrimidine was as follows: first, 2-chloropyrimidine (1.145 g, 20 mmol) was dissolved in ethanol (30 mL). Subsequently, an excess of 85% hydrazine hydrate (6 mL) was slowly added to the above solution under continuous stirring. The reaction mixture gradually changed to a bright yellow solution and white needle-like crystals were precipitated after 2 hours. The crystals were collected by filtration and recrystallized in ethanol to afford the target product 2-hydrazinopyrimidine in 80% yield. Next, 3-methylsalicylaldehyde (1.36 g, 10 mmol) was added to an ethanolic solution (30 mL) of 2-hydrazinopyrimidine (1.10 g, 10 mmol) and the formation of a pale yellow precipitate was immediately observed. After refluxing the reaction mixture for 3 h, the precipitate was filtered and collected and washed with ethanol to give a final light yellow H2mphp powder in 95% yield.
References
[1] Patent: WO2018/64119, 2018, A1. Location in patent: Paragraph 1484
[2] Journal of Organic Chemistry, 1999, vol. 64, # 15, p. 5644 - 5649
[3] Patent: US2003/187014, 2003, A1
[4] Journal of Coordination Chemistry, 2016, vol. 69, # 7, p. 1218 - 1225
[5] Journal of Physical Organic Chemistry, 2015, vol. 28, # 2, p. 108 - 115
2(1H)-Pyrimidinone, hydrazone (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
2(1H)-Pyrimidinone, hydrazone (9CI) Suppliers
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- Fax
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- info@chemstep.com
- Country
- Europe
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- 6143
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View Lastest Price from 2(1H)-Pyrimidinone, hydrazone (9CI) manufacturers
- Product
- 2(1H)-Pyrimidinone, hydrazone (9CI) 7504-94-1
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-11-13
- Product
- 2(1H)-Pyrimidinone, hydrazone (9CI) 7504-94-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-28
- Product
- 2(1H)-Pyrimidinone, hydrazone (9CI) 7504-94-1
- Price
- US $1.00-1.00/Kg/Drum
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2020-05-14