2,4-Dichloro-5-thiazolecarboxylic acid
- Product Name
- 2,4-Dichloro-5-thiazolecarboxylic acid
- CAS No.
- 62019-56-1
- Chemical Name
- 2,4-Dichloro-5-thiazolecarboxylic acid
- Synonyms
- 2,4-Dichloro-5-thiazolecarboxylic acid;dichloro-1,3-thiazole-5-carboxylic acid;5-Thiazolecarboxylic acid, 2,4-dichloro-;Thiazole-5-carboxylic acid, 2,4-dichloro-;2,4-DICHLORO-5-THIAZOLECARBOXYLIC ACID, 98% [62019-56-1
- CBNumber
- CB31094157
- Molecular Formula
- C4HCl2NO2S
- Formula Weight
- 198.03
- MOL File
- 62019-56-1.mol
2,4-Dichloro-5-thiazolecarboxylic acid Property
- Boiling point:
- 385.0±45.0 °C(Predicted)
- Density
- 1.824±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 1.05±0.28(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2934100090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D435988
- Product name
- 2,4-Dichloro-5-thiazolecarboxylicacid
- Packaging
- 50mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FD152100
- Product name
- 2,4-Dichloro-5-thiazolecarboxylicacid
- Packaging
- 25mg
- Price
- $67
- Updated
- 2021/12/16
- Product number
- 072323
- Product name
- 2,4-Dichloro-5-thiazolecarboxylic acid
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $79
- Updated
- 2021/12/16
- Product number
- FD152100
- Product name
- 2,4-Dichloro-5-thiazolecarboxylicacid
- Packaging
- 50mg
- Price
- $117
- Updated
- 2021/12/16
- Product number
- 072323
- Product name
- 2,4-Dichloro-5-thiazolecarboxylic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $177
- Updated
- 2021/12/16
2,4-Dichloro-5-thiazolecarboxylic acid Chemical Properties,Usage,Production
Uses
2,4-Dichloro-5-thiazolecarboxylic acid is an organic synthesis intermediate, widely used in the synthesis of thiazole compounds in the pharmaceutical and pesticide industries. It has multiple biological activities such as antibacterial, antifungal, anti-inflammatory, and antitumor.
Synthesis
92972-48-0
62019-56-1
General procedure for the synthesis of 2,4-dichloro-5-thiazole carboxylic acid from 2,4-dichlorothiazole-5-carboxaldehyde: To a mixed solution of 2,4-dichlorothiazole-5-carboxaldehyde (500 mg, 2.74 mmol) in tetrahydrofuran (18 ml) and water (12 ml) was added sulfonamide (346 mg, 3.56 mmol) and sodium chlorite (323 mg, 3.56 mmol) to an aqueous solution (2 ml). The reaction mixture was stirred at room temperature for 2 h. After completion of the reaction, it was diluted with ethyl acetate and washed with deionized water. The organic phase was separated and concentrated under reduced pressure to give the target product 2,4-dichloro-5-thiazolecarboxylic acid (440 mg, 88% yield) as a yellow solid.
References
[1] Patent: US2009/270456, 2009, A1. Location in patent: Page/Page column 8
2,4-Dichloro-5-thiazolecarboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,4-Dichloro-5-thiazolecarboxylic acid manufacturers
- Product
- 5-Thiazolecarboxylic acid, 2,4-dichloro- 62019-56-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-14