ChemicalBook > CAS DataBase List > H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH

H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH

Product Name
H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH
CAS No.
131580-10-4
Chemical Name
H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH
Synonyms
β-Amyloid 1-16;DAEFRHDSGYEVHHQK;BETA-AMYLOID (1-16);Bate-Amyloid (1-16);β-Amyloid (1-16), human;AMyloid b-Protein (1-16);Amyloid β-Protein (1-16);Amyloid ?2-Protein (1-16);AMYLOID BETA-PROTEIN (1-16);Beta-Amyloid (1-16) Peptide
CBNumber
CB3110326
Molecular Formula
C84H119N27O28
Formula Weight
1955.01
MOL File
131580-10-4.mol
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H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH Property

Density 
1.57±0.1 g/cm3(Predicted)
storage temp. 
-15°C
solubility 
Soluble in DMSO
form 
Solid
color 
White to off-white
Water Solubility 
Soluble in water or aqueous buffer
Sequence
H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-OH
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
A2275-58B
Product name
β-Amyloid [1-16]
Packaging
1mg
Price
$531
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA108823
Product name
Amyloid beta-Protein (1-16) trifluoroacetate salt
Packaging
10mg
Price
$636
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0000658
Product name
BETA-AMYLOID (1-16)
Purity
95.00%
Packaging
1MG
Price
$636.7
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364307
Product name
Beta-Amyloid (1-16)
Purity
> 95%
Packaging
5mg
Price
$736.1
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364308
Product name
Beta-Amyloid (1-16)
Purity
> 95%
Packaging
5mg
Price
$788.8
Updated
2021/12/16
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H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH Chemical Properties,Usage,Production

Uses

Aβ(s) peptides, their peptide fragments and mutated fragments are used to study a wide range of metabolic and regulatory functions including activation of kinases, regulation of cholesterol transport, function as a transcription factor, and regulators of inflammation. Aβ(s) peptides and their peptide fragments are also used to study oxidative stress, metal binding and mechanisms of protein cross-linking in the context of diseases such as Alzheimer?s disease and neurodegeneration.

in vivo

β-amyloid (1-16) fragment is considered as valid models to examine the contribution of the key histidine residues (His , His in mouse and His , His , His in human fragments) to the Ab–Cu2+ interaction. Oxidation targets for β-Amyloid (1-16) are the histidine residues coordinated to the metal ions. Copper is bound to Aβ in senile plaque of Alzheimer’s disease with β-Amyloid (1-16) taking part in the coordination of the Cu2+ ions. Cu2+ and Zn2+ are linked with the neurotoxicity of -Amyloid and free radical damage[1]. β-amyloid (1-16) is the minimal amino acidic sequence display a Cu coordination mode which involves three Histidines (His6, His13 and His14). β-amyloid (1-16) is supposed to be involved in metal binding[2]. Human β-amyloid interacts with zinc ions through its metal-binding domain 1-16. The C-tails of the two polypeptide chains of the rat Aβ(1-16) dimer are oriented in opposite directions to each other, which hinders the assembly of rat Aβ dimers into oligomeric aggregates. Thus, the differences in the structure of zinc-binding sites of human and rat β-Amyloid (1-16), their ability to form regular cross-monomer bonds, and the orientation of their hydrophobic C-tails could be responsible for the resistance of rats to Alzheimer's disease[3].

H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH Suppliers

China 67 Japan 1 United Kingdom 1 United States 7 Global 76
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Cellmano Biotech Limited
Tel
0551-65326643 18156095617
Fax
0551-65326641
Email
info@cellmano.com
Country
China
ProdList
1010
Advantage
55
Creative Peptides
Tel
Email
info@creative-peptides.com
Country
United States
ProdList
6083
Advantage
56
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 18101056239
Email
3193328036@qq.com
Country
China
ProdList
29760
Advantage
68
Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5501
Advantage
55
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 15951641583
Fax
025-58361106-806
Email
zhao.xu@njpeptide.com
Country
China
ProdList
9979
Advantage
55
Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
4802
Advantage
58
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
7408
Advantage
58
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View Lastest Price from H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Bate-Amyloid (1-16) 131580-10-4
Price
US $0.10-0.30/kg
Min. Order
1kg
Purity
>98%
Supply Ability
20 tons
Release date
2024-01-06
Zibo Hangyu Biotechnology Development Co., Ltd
Product
[Gln11] -Bate- Amyloid (1 - 16) 131580-10-4
Price
US $0.10-0.30/kg
Min. Order
1kg
Purity
>95%
Supply Ability
20 tons
Release date
2024-01-08

131580-10-4, H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OHRelated Search:

Amyloid β-Protein (3-42) AMYLOID BETA-PROTEIN (HUMAN, 25-35) TRIFLUOROACETATE Amyloid β-Protein (1-42) (mouse, rat) Amyloid β-Peptide (1-42) (human) Amyloid β-Protein (1-12) AMYLOID BETA-PROTEIN (1-40) (MOUSE, RAT) Amyloid β-Protein (3-40) Amyloid Beta-Protein (1-14) H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH Amyloid β-Protein (4-42) H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-OH H-MET-LEU-GLY-ILE-ILE-ALA-GLY-LYS-ASN-SER-GLY-OH BETA-AMYLOID (1-43) β-Amyloid (18-28) AMYLOID BETA-PROTEIN (29-40) β-Amyloid（1-40) Amyloid beta-Protein (17-40) ammonium salt β-Amyloid (13-27)

  • BETA-AMYLOID (1-16)
  • DAEFRHDSGYEVHHQK
  • H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH
  • AMyloid b-Protein (1-16)
  • AMYLOID BETA-PROTEIN (1-16)
  • Amyloid beta-Protein (1-16) trifluoroacetate salt
  • L-Lysine, L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-α-aspartyl-L-serylglycyl-L-tyrosyl-L-α-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-
  • [Gln11] -β- Amyloid (1 - 16)
  • β-Amyloid 1-16
  • Amyloidβ-Protein(1-16)/β-Amyloid(1-16),human
  • H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH USP/EP/BP
  • Amyloid β-Protein (1-16)
  • β-Amyloid (1-16), human
  • Amyloid β-Protein (1-16) trifluoroacetate salt
  • Bate-Amyloid (1-16)
  • [Gln11] -Bate- Amyloid (1 - 16)
  • Beta-Amyloid (1-16) Peptide
  • Amyloid ?2-Protein (1-16)
  • 131580-10-4
  • 31580-10-4
  • C84H119N27O28
  • peptide