H-TRP-PHE-TYR-SER(PO3H2)-PRO-ARG-PNA

Product Name: H-TRP-PHE-TYR-SER(PO3H2)-PRO-ARG-PNA
CAS No.: 202739-41-1
Chemical Name: H-TRP-PHE-TYR-SER(PO3H2)-PRO-ARG-PNA
Synonyms: H-TRP-PHE-TYR-SER(PO3H2)-PRO-ARG-PNA;H-Trp-Phe-Tyr-Ser(PO?H?)-Pro-Arg-pNA;H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA trifluoroacetate salt;L-Argininamide, L-tryptophyl-L-phenylalanyl-L-tyrosyl-O-phosphono-L-seryl-L-prolyl-N-(4-nitrophenyl)- (9CI)
CBNumber: CB3111202
Molecular Formula: C49H59N12O13P
Formula Weight: 1055.04
MOL File: Mol file

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H-TRP-PHE-TYR-SER(PO3H2)-PRO-ARG-PNA Property

Density: 1.53±0.1 g/cm3(Predicted)
storage temp.: -15°C
pka: 1.80±0.10(Predicted)
Sequence: Trp-Phe-Tyr-{PO2}-Ser-Pro-Arg

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Chem-Impex

Product number: 32863
Product name: H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNAtrifluoroacetatesalt
Packaging: 1MG
Price: $186.37
Updated: 2021/12/16

Chem-Impex

Product number: 32863
Product name: H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNAtrifluoroacetatesalt
Packaging: 5MG
Price: $745.47
Updated: 2021/12/16

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H-TRP-PHE-TYR-SER(PO3H2)-PRO-ARG-PNA Chemical Properties,Usage,Production

Uses

H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is a chromogenic substrate for Pin1. Pin1 is an essential and conserved mitotic peptidyl-prolyl isomerase, and can recognize the phosphoserine-proline bonds present in mitotic phosphoproteins[1][2].

References

[1] M B Yaffe, et al. Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism. Science. 1997 Dec 12;278(5345):1957-60. DOI:10.1126/science.278.5345.1957
[2] Kelly E Duncan, et al. Discovery and characterization of a nonphosphorylated cyclic peptide inhibitor of the peptidylprolyl isomerase, Pin1. J Med Chem. 2011 Jun 9;54(11):3854-65. DOI:10.1021/jm200156c

H-TRP-PHE-TYR-SER(PO3H2)-PRO-ARG-PNA Preparation Products And Raw materials

Raw materials

Preparation Products

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H-TRP-PHE-TYR-SER(PO3H2)-PRO-ARG-PNA Suppliers

China 32 United States 1 Global 33

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202739-41-1, H-TRP-PHE-TYR-SER(PO3H2)-PRO-ARG-PNARelated Search:

Glutathione Ethyl Ester Acetyl Hexapeptide-46 Oligopeptide-108 Nicotinoyl Tripeptide-35 EMD 270179 Oligopeptide-81 (Asp28)-Exenatide Hexapeptide-22 Hexapeptide-7 Octapeptide-8

H-TRP-PHE-TYR-SER(PO3H2)-PRO-ARG-PNA

L-Argininamide, L-tryptophyl-L-phenylalanyl-L-tyrosyl-O-phosphono-L-seryl-L-prolyl-N-(4-nitrophenyl)- (9CI)

H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA trifluoroacetate salt

H-Trp-Phe-Tyr-Ser(PO?H?)-Pro-Arg-pNA

202739-41-1