Nepicastat
- Product Name
- Nepicastat
- CAS No.
- 173997-05-2
- Chemical Name
- Nepicastat
- Synonyms
- SYN117;CS-853;Nepitat;Nepicastat;RS-25560-197;Nepicastat HCl;Nepicastat [inn];Nepicastat (SYN 117);Nepicastat (free base) (SYN-117);SYN117;RS-25560-197;SYN-117;SYN 117
- CBNumber
- CB31116989
- Molecular Formula
- C14H15F2N3S
- Formula Weight
- 295.35
- MOL File
- 173997-05-2.mol
Nepicastat Property
- Boiling point:
- 401.8±55.0 °C(Predicted)
- Density
- 1.40
- storage temp.
- Store at -20°C
- solubility
- DMSO: ≥ 48 mg/mL (162.52 mM)
- form
- Powder
- pka
- 11.69±0.70(Predicted)
N-Bromosuccinimide Price
- Product number
- 474143
- Product name
- Nepicastat
- Packaging
- 100mg
- Price
- $1890
- Updated
- 2021/12/16
- Product number
- 093133
- Product name
- (S)-5-(Aminomethyl)-1-(5,7-difluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-1H-imidazole-2(3H)-thione
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $5670
- Updated
- 2021/12/16
- Product number
- INB0000869
- Product name
- NEPICASTAT
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $8610
- Updated
- 2021/12/16
- Product number
- INB0000869
- Product name
- NEPICASTAT
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $9435.2
- Updated
- 2021/12/16
- Product number
- INB0000869
- Product name
- NEPICASTAT
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $1006.58
- Updated
- 2021/12/16
Nepicastat Chemical Properties,Usage,Production
Uses
Treatment of congestive heart failure (dopamine β-hydroxylase inhibitor).
Definition
ChEBI: Nepicastat is a member of the class of 1,3-dihydroimidazole-2-thiones that is 1,3-dihydro-2H-imidazole-2-thione in which one of the nitrogens is substituted by a 5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl group while the carbon adjacent to it is substituted by an aminomethyl group (the S enantiomer). It is a potent and selective inhibitor of both bovine and human dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine. It has a role as an EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor. It is a member of tetralins, an organofluorine compound, a primary amino compound and a member of 1,3-dihydroimidazole-2-thiones.
target
DBH
Nepicastat Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Nepicastat manufacturers
- Product
- Nepicastat 173997-05-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- Nepicastat 173997-05-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- Nepicastat 173997-05-2
- Price
- US $1.00/KG
- Min. Order
- 1G
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-08-20