Pomisartan

Product Name: Pomisartan
CAS No.: 144702-17-0
Chemical Name: Pomisartan
Synonyms: BIBR363;BIBR 363;BIBR-363;Pomisartan;Unii-7539319jyi;Pomisartan [inn];4'-((2-Ethyl-4-methyl-6-(5,6,7,8-tetrahydroimidazo(1,2-A)pyridin-2-yl)-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid;[1,1'-Biphenyl]-2-carboxylic acid, 4'-[[2-ethyl-4-methyl-6-(5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-2-yl)-1H-benzimidazol-1-yl]methyl]-
CBNumber: CB31117401
Molecular Formula: C31H30N4O2
Formula Weight: 490.6
MOL File: 144702-17-0.mol

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Pomisartan Property

Boiling point:: 779.5±60.0 °C(Predicted)
Density: 1.27±0.1 g/cm3(Predicted)
pka: 3.86±0.36(Predicted)

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Hazard and Precautionary Statements (GHS)

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Pomisartan Chemical Properties,Usage,Production

Uses

Pomisartan is an orally active angiotensin II receptor type AT1 antagonist (IC50=0.26 μM). Pomisartan works by inhibiting the binding of angiotensin II to the AT1 receptor, thereby blocking the vasoconstriction and aldosterone release caused by this interaction. Pomisartan results in a blood pressure-lowering effect[1].

References

[1] Krovat EM, et al. Non-peptide angiotensin II receptor antagonists: chemical feature based pharmacophore identification. J Med Chem. 2003 Feb 27;46(5):716-26. DOI:10.1021/jm021032v

Pomisartan Preparation Products And Raw materials

Raw materials

Preparation Products

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Pomisartan Suppliers

China 7 United States 4 Global 11

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Suzhou Meishi Biotechnology Co., Ltd.

Tel: 1173954148q
Email: meishipharma@126.com
Country: China
ProdList: 20033
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Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
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TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29423
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
Advantage: 58

TargetMol Chemicals Inc.

Tel: +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 19962
Advantage: 58

144702-17-0, PomisartanRelated Search:

2-ETHYL-4-METHYL IMIDAZOLE ACETATE 4'-METHYL-BIPHENYL-2-CARBALDEHYDE Pomisartan 4'-Methylbiphenyl-2-carboxylic acid

Pomisartan

4'-((2-Ethyl-4-methyl-6-(5,6,7,8-tetrahydroimidazo(1,2-A)pyridin-2-yl)-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid

Pomisartan [inn]

Unii-7539319jyi

[1,1'-Biphenyl]-2-carboxylic acid, 4'-[[2-ethyl-4-methyl-6-(5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-2-yl)-1H-benzimidazol-1-yl]methyl]-

BIBR 363

BIBR363

BIBR-363

144702-17-0

C31H30N4O2