ChemicalBook > CAS DataBase List > KRP-203
KRP-203
- Product Name
- KRP-203
- CAS No.
- 509088-69-1
- Chemical Name
- KRP-203
- Synonyms
- KRP-203;KRP-203 HCl;KRP-203 (hydrochloride);Mocravimod hydrochloride;Mocravimod (KRP-203) HCl;Mocravimod dihydrochloride;Mocravimod hydrochloride, 10 mM in DMSO;2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol;2-Amino-2-[2-[2-chloro-4-[[3-(benzyloxy)phenyl]thio]phenyl]-ethyl]-1,3-propanediol HCl;2-AMINO-2-[2-[2-CHLORO-4-[[3-(PHENYLMETHOXY)PHENYL]THIO]PHENYL]ETHYL]-1,3-PROPANEDIOL HCL
- CBNumber
- CB31176381
- Molecular Formula
- C24H27Cl2NO3S
- Formula Weight
- 480.45
- MOL File
- 509088-69-1.mol
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KRP-203 Property
- Melting point:
- 199-200 ºC (DEC.)
- storage temp.
- Refrigerator
- solubility
- DMSO, Methanol
- form
- Solid
- color
- White to Off-White
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Usbiological
- Product number
- 281117
- Product name
- KRP-203
- Packaging
- 50mg
- Price
- $5699
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0000619
- Product name
- KRP-203
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $401.32
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0000619
- Product name
- KRP-203
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $413.2
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0000619
- Product name
- KRP-203
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $730
- Updated
- 2021/12/16
Chemenu
- Product number
- CM186548
- Product name
- 2-Amino-2-(4-((3-(benzyloxy)phenyl)thio)-2-chloro-phenethyl)propane-1,3-diolhydrochloride
- Purity
- 95%
- Packaging
- 1g
- Price
- $1234
- Updated
- 2021/12/16
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KRP-203 Chemical Properties,Usage,Production
Uses
A novel immunomodulator
Uses
A novel sphingosine-1-phosphate receptor agonists in the treatment of autoimmune diseases. Immunosuppressant.
in vivo
Mocravimod hydrochloride (KRP-203) ameliorates atherosclerosis in LDL-R / Mice[1].
Mocravimod hydrochloride (KRP-203) (orally; 0.1 and 1 mg/kg/day; for 100 days) prolongs graft survival and attenuates chronic rejection in mHC-disparate rat heart allografts[2].
| Animal Model: | Inbred male DA (MHC haplotype: RT1a) rats[2] |
| Dosage: | 0.1 and 1 mg/kg |
| Administration: | Orally; daily; for 100 days |
| Result: | Prolonged graft survival and attenuated chronic rejection in mHC-disparate rat heart allografts. |
KRP-203 Preparation Products And Raw materials
Raw materials
Preparation Products
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KRP-203 Suppliers
- Tel
- --
- Fax
- --
- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
- Advantage
- 71