ChemicalBook > CAS DataBase List > KRP-203

KRP-203

Product Name
KRP-203
CAS No.
509088-69-1
Chemical Name
KRP-203
Synonyms
KRP-203;KRP-203 HCl;KRP-203 (hydrochloride);Mocravimod hydrochloride;Mocravimod (KRP-203) HCl;Mocravimod dihydrochloride;Mocravimod hydrochloride, 10 mM in DMSO;2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol;2-Amino-2-[2-[2-chloro-4-[[3-(benzyloxy)phenyl]thio]phenyl]-ethyl]-1,3-propanediol HCl;2-AMINO-2-[2-[2-CHLORO-4-[[3-(PHENYLMETHOXY)PHENYL]THIO]PHENYL]ETHYL]-1,3-PROPANEDIOL HCL
CBNumber
CB31176381
Molecular Formula
C24H27Cl2NO3S
Formula Weight
480.45
MOL File
509088-69-1.mol
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KRP-203 Property

Melting point:
199-200 ºC (DEC.)
storage temp. 
Refrigerator
solubility 
DMSO, Methanol
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological
Product number
281117
Product name
KRP-203
Packaging
50mg
Price
$5699
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000619
Product name
KRP-203
Purity
95.00%
Packaging
1MG
Price
$401.32
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000619
Product name
KRP-203
Purity
95.00%
Packaging
10MG
Price
$413.2
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000619
Product name
KRP-203
Purity
95.00%
Packaging
250MG
Price
$730
Updated
2021/12/16
Chemenu
Product number
CM186548
Product name
2-Amino-2-(4-((3-(benzyloxy)phenyl)thio)-2-chloro-phenethyl)propane-1,3-diolhydrochloride
Purity
95%
Packaging
1g
Price
$1234
Updated
2021/12/16
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KRP-203 Chemical Properties,Usage,Production

Uses

A novel immunomodulator

Uses

A novel sphingosine-1-phosphate receptor agonists in the treatment of autoimmune diseases. Immunosuppressant.

in vivo

Mocravimod hydrochloride (KRP-203) ameliorates atherosclerosis in LDL-R / Mice[1].
Mocravimod hydrochloride (KRP-203) (orally; 0.1 and 1 mg/kg/day; for 100 days) prolongs graft survival and attenuates chronic rejection in mHC-disparate rat heart allografts[2].

Animal Model:Inbred male DA (MHC haplotype: RT1a) rats[2]
Dosage:0.1 and 1 mg/kg
Administration:Orally; daily; for 100 days
Result:Prolonged graft survival and attenuated chronic rejection in mHC-disparate rat heart allografts.

KRP-203 Preparation Products And Raw materials

Raw materials

Preparation Products

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KRP-203 Suppliers

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509088-69-1, KRP-203Related Search:

KRP-203

  • 2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol Hydrochloride
  • KRP-203
  • 2-Amino-2-(2-(4-(3-benzyloxyphenylthio)-2-chlorophenyl)ethyl)-1,3-propanediol hydrochloride
  • KRP-203 (hydrochloride)
  • 2-Amino-2-(4-((3-(benzyloxy)phenyl)thio)-2-chloro-phenethyl)propane-1,3-diol hydrochloride
  • KRP203/2-AMino-2-(2-(4-(3-benzyloxyphenylthio)-2-chlorophenyl)ethyl)-1,3-propanediol hydrochloride
  • 2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol
  • 2-AMINO-2-[2-[2-CHLORO-4-[[3-(PHENYLMETHOXY)PHENYL]THIO]PHENYL]ETHYL]-1,3-PROPANEDIOL HCL
  • KRP-203 HCl
  • 2-amino-2-[2-[2-chloro-4-(3-phenylmethoxyphenyl)sulfanylphenyl]ethyl]propane-1,3-diol,hydrochloride
  • Mocravimod dihydrochloride
  • Mocravimod hydrochloride
  • 1,3-Propanediol, 2-amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-, hydrochloride (1:1)
  • 2-amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-Propanediol hydrochloride (1:1)
  • LPL Receptor,inhibit,KRP 203,KRP203,Mocravimod hydrochloride,Lysophospholipid Receptor,Inhibitor,Mocravimod
  • Mocravimod (KRP-203) HCl
  • Mocravimod hydrochloride, 10 mM in DMSO
  • 2-Amino-2-[2-[2-chloro-4-[[3-(benzyloxy)phenyl]thio]phenyl]-ethyl]-1,3-propanediol HCl
  • 509088-69-1
  • C24H27Cl2NO3S
  • C24H26ClNO3SHCl
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Amines
  • Aromatics
  • Sulfur & Selenium Compounds