N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride

Product Name: N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride
CAS No.: 1177141-67-1
Chemical Name: N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride
Synonyms: CKI-7 2HCL;CKI-7 dihydrochlorid;CKI-7 Dihydrochloride;CKI-7 (hydrochloride);N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide dihydrochloride;N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride;Serum and glucocorticoid-regulated kinase,inhibit,nestin,S6K,Inhibitor,CK1,Casein Kinase,Ribosomal S6 Kinase (RSK),differentiation,SGK,CKI-7,Cyclin dependent kinase,neural,Serum-glucocorticoid regulated kinase,S6K1,MSK1,CDK,CKI 7,Wnt,CKI7,βIII-tubulin,Sox1
CBNumber: CB31176497
Molecular Formula: C11H14Cl3N3O2S
Formula Weight: 358.67176
MOL File: 1177141-67-1.mol

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N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride Property

Melting point:: 187-189°C
storage temp.: -20°C
solubility: H2O: >5mg/mL
form: solid
color: white to light tan

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed
Precautionary statements: P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C0742
Product name: CKI-7 dihydrochloride
Purity: ≥98% (HPLC), solid
Packaging: 5mg
Price: $211
Updated: 2024/03/01

Sigma-Aldrich

Product number: C0742
Product name: CKI-7 dihydrochloride
Purity: ≥98% (HPLC), solid
Packaging: 25mg
Price: $883
Updated: 2024/03/01

Cayman Chemical

Product number: 28268
Product name: CKI-7 (hydrochloride)
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 28268
Product name: CKI-7 (hydrochloride)
Packaging: 25mg
Price: $533
Updated: 2024/03/01

Cayman Chemical

Product number: 28268
Product name: CKI-7 (hydrochloride)
Packaging: 5mg
Price: $161
Updated: 2024/03/01

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N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride Chemical Properties,Usage,Production

Chemical Properties

Beige Solid

Uses

Found to have a potent inhibitory action against casein kinase 1 completely with respect to ATP and a much weaker effect on casein kinase 2 and other protein kinases

Biochem/physiol Actions

CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1. CKI-7 inhibits SGK as potently as CK1. IC50 = 6 μM.

storage

Store at -20°C

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride Suppliers

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1177141-67-1, N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide DihydrochlorideRelated Search:

Choline kinase alpha 5-CHLOROISOQUINOLINE

CKI-7 Dihydrochloride

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride

CKI-7 dihydrochlorid

N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide dihydrochloride

CKI-7 2HCL

Serum and glucocorticoid-regulated kinase,inhibit,nestin,S6K,Inhibitor,CK1,Casein Kinase,Ribosomal S6 Kinase (RSK),differentiation,SGK,CKI-7,Cyclin dependent kinase,neural,Serum-glucocorticoid regulated kinase,S6K1,MSK1,CDK,CKI 7,Wnt,CKI7,βIII-tubulin,Sox1

CKI-7 (hydrochloride)

1177141-67-1

C11H14Cl3N3O2S

Inhibitors

Protein Kinase Inhibitors and Activators

All Inhibitors