Carfimate

Carfimate Property

Melting point:

86-87°

Boiling point:

306.47°C (rough estimate)

Density 

1.1999 (rough estimate)

refractive index 

1.5460 (estimate)

pka

12.77±0.50(Predicted)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Carfimate Chemical Properties,Usage,Production

Uses

Phenylethynylcarbinol carbamate is a agent used for neurology disease[1]. Phenylethynylcarbinol carbamate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Definition

ChEBI: Carfimate is a carboxylic ester. It is functionally related to a benzyl alcohol.

Safety Profile

Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. See also CARBAMATES

References

[1] GHISONI T. A proposito di un nuovo ipnotico, carbammato di fenil-etinil-carbinolo [A new hypnotic drug, phenylethynylcarbinol carbamate]. Gazz Med Ital. 1956;115(8):242-247. PMID:13375868