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RAC 8-HYDROXY EFAVIRENZ

Product Name
RAC 8-HYDROXY EFAVIRENZ
CAS No.
205754-33-2
Chemical Name
RAC 8-HYDROXY EFAVIRENZ
Synonyms
8-HydroxyEfavirenz;RAC 8-HYDROXY EFAVIRENZ;Efavirenz Impurity 11(8-Hydroxy Efavirenz);(4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one;6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one;2H-3,1-Benzoxazin-2-one,6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-;(S)-6-Chloro-4-(cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one;2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-;8-Hydroxy EfavirenzQ: What is 8-Hydroxy Efavirenz Q: What is the CAS Number of 8-Hydroxy Efavirenz Q: What is the storage condition of 8-Hydroxy Efavirenz Q: What are the applications of 8-Hydroxy Efavirenz
CBNumber
CB7501021
Molecular Formula
C14H9ClF3NO3
Formula Weight
331.67
MOL File
205754-33-2.mol
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RAC 8-HYDROXY EFAVIRENZ Property

Melting point:
144-154°C
Boiling point:
373.6±42.0 °C(Predicted)
Density 
1?+-.0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Acetonitrile: soluble; DMSO: soluble; Methanol: soluble
form 
A solid
pka
7.18±0.40(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27853
Product name
8-hydroxy Efavirenz
Packaging
1mg
Price
$605
Updated
2024/03/01
Usbiological
Product number
H9044-30
Product name
rac 8-Hydroxy Efavirenz
Packaging
1mg
Price
$460
Updated
2021/12/16
TRC
Product number
H941830
Product name
8-HydroxyEfavirenz(~90%)
Packaging
2.5mg
Price
$6595
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
51706
Product name
8-HydroxyEfavirenz
Packaging
50mg
Price
$7500
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010043
Product name
8-HYDROXYEFAVIRENZ
Purity
95.00%
Packaging
5MG
Price
$504.72
Updated
2021/12/16
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RAC 8-HYDROXY EFAVIRENZ Chemical Properties,Usage,Production

Description

8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz . 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic spines in rat primary hippocampal neuronal cultures when used at a concentration of 0.01 μM.

Chemical Properties

Off-White Solid

Uses

A labellebed metabolite of Efavirenz, a nonnucleoside HIV-1 reverse transcriptase inhibitor

Uses

8-Hydroxy Efavirenz is a metabolite of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor.

RAC 8-HYDROXY EFAVIRENZ Preparation Products And Raw materials

Raw materials

Preparation Products

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RAC 8-HYDROXY EFAVIRENZ Suppliers

Shanghai Devinchem Ltd
Tel
027-65318838 13646286950
Email
sales@devinchem.com
Country
China
ProdList
2997
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58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Shanghai SuperLan Chemcial Technique Centre
Tel
021-2022843681 15618226720
Fax
+86-21-51601218
Email
lucy@atkchemical.com
Country
China
ProdList
9952
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57423
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Guangzhou Dreampharm Biotechnology Co., Ltd.
Tel
020-36607679 17825480238
Fax
QQ 3008233717
Email
3008233746@qq.com
Country
China
ProdList
9919
Advantage
12

205754-33-2, RAC 8-HYDROXY EFAVIRENZRelated Search:


  • RAC 8-HYDROXY EFAVIRENZ
  • 8-HydroxyEfavirenz
  • 6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
  • (4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
  • Efavirenz Impurity 11(8-Hydroxy Efavirenz)
  • 2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-
  • 8-Hydroxy EfavirenzQ: What is 8-Hydroxy Efavirenz Q: What is the CAS Number of 8-Hydroxy Efavirenz Q: What is the storage condition of 8-Hydroxy Efavirenz Q: What are the applications of 8-Hydroxy Efavirenz
  • 2H-3,1-Benzoxazin-2-one,6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-
  • (S)-6-Chloro-4-(cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one
  • 205754-33-2
  • Intermediates & Fine Chemicals
  • Isotope Labeled Compounds
  • Metabolites
  • Non-nucleoside Reverse Transcriptase
  • Pharmaceuticals