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Metoprine

Product Name
Metoprine
CAS No.
7761-45-7
Chemical Name
Metoprine
Synonyms
DDMP;U-197;BW 197U;SK 5265;NSC 7364;NSC-19494;BW-50-197;Metoprine;methodichlorophen;Metoprine, 10 mM in DMSO
CBNumber
CB31179180
Molecular Formula
C11H10Cl2N4
Formula Weight
269.13
MOL File
7761-45-7.mol
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Metoprine Property

Melting point:
275-276℃
Boiling point:
418.42°C (rough estimate)
Density 
1.447
refractive index 
1.6300 (estimate)
storage temp. 
Hygroscopic, Refrigerator, under inert atmosphere
solubility 
DMSO (Slightly, Heated), Methanol (Slightly, Heated, Sonicated)
form 
Solid
pka
6.80±0.10(Predicted)
color 
Off-White to Light Yellow
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
M338835
Product name
Metoprine
Packaging
25mg
Price
$185
Updated
2021/12/16
Usbiological
Product number
017618
Product name
Metoprine
Packaging
25mg
Price
$460
Updated
2021/12/16
ChemScene
Product number
CS-0105542
Product name
Metoprine
Purity
99.04%
Packaging
10mg
Price
$110
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0009149
Product name
METOPRINE
Purity
95.00%
Packaging
1MG
Price
$154.35
Updated
2021/12/16
ChemScene
Product number
CS-0105542
Product name
Metoprine
Purity
99.04%
Packaging
50mg
Price
$320
Updated
2021/12/16
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Metoprine Chemical Properties,Usage,Production

Uses

A 2,4-Diaminopyrimidine derivative as antimalarial agent.

in vivo

Metoprine (BW 197U; 2-10 mg/kg; IP) ameliorates the memory deficits induced by nucleus basalis magnocellularis (NBM) lesions in a dose-dependent manner[2].
Intraperitoneal administration of Metoprine produces various behavioral effects, including decreases in food intake and increases in water consumption[1].

Animal Model:Male Sprague-dawley rats (200-280g)[2]
Dosage:2, 5, 10 mg/kg
Administration:IP
Result:Ameliorated the memory deficits induced by nucleus basalis magnocellularis (NBM) lesions in a dose-dependent manner and significanty prolonged transfer latency at a high dose of 10 mg/kg.

Metoprine Preparation Products And Raw materials

Raw materials

Preparation Products

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Metoprine Suppliers

Canada 1 China 42 United States 8 Global 51
J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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96815
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Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
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China
ProdList
15402
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Atop-Pharma (Shanghai) Technology Co., Ltd.
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+86 (21) 5196-9732
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+86 (21) 5196-9733
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China
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996
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Tianjin Derchemist Science & Technology Co., Ltd.
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22-58627059 13920586291
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022-58620305
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zdcomcon@126.com
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China
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4015
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
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400-6206333 13167063860
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021-50323701
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anhua.mao@aladdin-e.com
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China
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26682
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Cato Research Chemicals Inc.
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020-81960175
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+1-541-2553641
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min.he@cato-chem.com
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China
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Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
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China
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Shanghai Chaolan Chemical Technology Center
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021-QQ：65489617 15618227136
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21-5161 9052
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Sales@ATKchemical.com
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China
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 18892239720
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010-60605840
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psaitong@jm-bio.com
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China
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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+86-400-002-6226 +86-13028896684;
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sales@rrkchem.com
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China
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57422
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7761-45-7, MetoprineRelated Search:

5-(4-CHLOROPHENYL)PYRIMIDIN-4-AMINE Etoprine Metoprine

  • 5-(3,4-dichlorophenyl)-6-MethylpyriMidine-2,4-diaMine
  • 5-(3,4-Dichlorophenyl)-6-Methyl-2,4-pyriMidinediaMine
  • BW 197U
  • NSC 7364
  • SK 5265
  • Metoprine
  • methodichlorophen
  • 2,4-DIAMINO-5-(3,4-DICHLOROPHENYL)-6-METHYLPYRIMIDINE
  • BW-50-197
  • DDMP
  • NSC-19494
  • U-197
  • Inhibitor,histamine,HMT,Antifolate,barrier,Metoprine,Histone Methyltransferase,antitumor,N-methyltransferase,diaminopyrimidine,inhibit,BW 197U,blood-brain
  • 2,4-Pyrimidinediamine, 5-(3,4-dichlorophenyl)-6-methyl-
  • Metoprine, 10 mM in DMSO
  • 7761-45-7
  • Bases & Related Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Nucleotides
  • Pharmaceuticals