Metoprine

Product Name: Metoprine
CAS No.: 7761-45-7
Chemical Name: Metoprine
Synonyms: DDMP;U-197;BW 197U;SK 5265;NSC 7364;NSC-19494;BW-50-197;Metoprine;methodichlorophen;Metoprine, 10 mM in DMSO
CBNumber: CB31179180
Molecular Formula: C11H10Cl2N4
Formula Weight: 269.13
MOL File: 7761-45-7.mol

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Metoprine Property

Melting point:: 275-276℃
Boiling point:: 418.42°C (rough estimate)
Density: 1.447
refractive index: 1.6300 (estimate)
storage temp.: Hygroscopic, Refrigerator, under inert atmosphere
solubility: DMSO (Slightly, Heated), Methanol (Slightly, Heated, Sonicated)
form: Solid
pka: 6.80±0.10(Predicted)
color: Off-White to Light Yellow
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: M338835
Product name: Metoprine
Packaging: 25mg
Price: $185
Updated: 2021/12/16

Usbiological

Product number: 017618
Product name: Metoprine
Packaging: 25mg
Price: $460
Updated: 2021/12/16

ChemScene

Product number: CS-0105542
Product name: Metoprine
Purity: 99.04%
Packaging: 10mg
Price: $110
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0009149
Product name: METOPRINE
Purity: 95.00%
Packaging: 1MG
Price: $154.35
Updated: 2021/12/16

ChemScene

Product number: CS-0105542
Product name: Metoprine
Purity: 99.04%
Packaging: 50mg
Price: $320
Updated: 2021/12/16

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Metoprine Chemical Properties,Usage,Production

Uses

A 2,4-Diaminopyrimidine derivative as antimalarial agent.

in vivo

Metoprine (BW 197U; 2-10 mg/kg; IP) ameliorates the memory deficits induced by nucleus basalis magnocellularis (NBM) lesions in a dose-dependent manner^[2].
Intraperitoneal administration of Metoprine produces various behavioral effects, including decreases in food intake and increases in water consumption^[1].

Animal Model:	Male Sprague-dawley rats (200-280g)^[2]
Dosage:	2, 5, 10 mg/kg
Administration:	IP
Result:	Ameliorated the memory deficits induced by nucleus basalis magnocellularis (NBM) lesions in a dose-dependent manner and significanty prolonged transfer latency at a high dose of 10 mg/kg.

Metoprine Preparation Products And Raw materials

Raw materials

Preparation Products

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Metoprine Suppliers

Canada 1 China 40 United States 8 Global 49

J & K SCIENTIFIC LTD.

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TargetMol Chemicals Inc.

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7761-45-7, MetoprineRelated Search:

5-(4-CHLOROPHENYL)PYRIMIDIN-4-AMINE Etoprine Metoprine

5-(3,4-dichlorophenyl)-6-MethylpyriMidine-2,4-diaMine

5-(3,4-Dichlorophenyl)-6-Methyl-2,4-pyriMidinediaMine

BW 197U

NSC 7364

SK 5265

Metoprine

methodichlorophen

2,4-DIAMINO-5-(3,4-DICHLOROPHENYL)-6-METHYLPYRIMIDINE

BW-50-197

DDMP

NSC-19494

U-197

Inhibitor,histamine,HMT,Antifolate,barrier,Metoprine,Histone Methyltransferase,antitumor,N-methyltransferase,diaminopyrimidine,inhibit,BW 197U,blood-brain

2,4-Pyrimidinediamine, 5-(3,4-dichlorophenyl)-6-methyl-

Metoprine, 10 mM in DMSO

7761-45-7

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