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Mitonafide

Product Name
Mitonafide
CAS No.
54824-17-8
Chemical Name
Mitonafide
Synonyms
Nsc300288;Mitonafide;Aids070527;Aids-070527;M-4212【pharmaceutical】;Mitonafide, 10 mM in DMSO;N-(2-(Dimethylamino)ethyl)-3-nitronaphthalimide;3-Nitro-N-(2-dimethylaminoethyl)-1,8-naphthalimide;2-[2-(Dimethylamino)ethyl]-5-nitro-1H-benz[de]isoquinoline-1,3(2H)-dione;2-[2-(Dimethylamino)ethyl]-5-nitro-1H-benzo[de]isoquinoline-1,3(2H)-dione
CBNumber
CB31179221
Molecular Formula
C16H15N3O4
Formula Weight
313.31
MOL File
54824-17-8.mol
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Mitonafide Property

Melting point:
138-139 °C(Solv: ethanol (64-17-5))
Boiling point:
496.8±30.0 °C(Predicted)
Density 
1.384±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
8.76±0.28(Predicted)
color 
Brown
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
M371990
Product name
Mitonafide
Packaging
50mg
Price
$315
Updated
2021/12/16
Usbiological
Product number
017682
Product name
Mitonafide
Packaging
25mg
Price
$446
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010547
Product name
3-NITRO-N-(2-DIMETHYLAMINOETHYL)-1,8-NAPHTHALIMIDE
Purity
95.00%
Packaging
25MG
Price
$739.2
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010547
Product name
3-NITRO-N-(2-DIMETHYLAMINOETHYL)-1,8-NAPHTHALIMIDE
Purity
95.00%
Packaging
250MG
Price
$1871.1
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010547
Product name
3-NITRO-N-(2-DIMETHYLAMINOETHYL)-1,8-NAPHTHALIMIDE
Purity
95.00%
Packaging
10MG
Price
$315
Updated
2021/12/16
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Mitonafide Chemical Properties,Usage,Production

Uses

A Naphthalimides with potent anticancer activity.

in vivo

Mitonafide (0.5 and 1 mg/kg, i.p., 1-7 days) shows antitumoral potency in S-180 bearing mice[4].
Mitonafide (5 mg/kg, i.p., twice a day) shows anticancer activity in HepG2 xenograft model[6].
Mitonafide (single i.p. injection, S-180 bearing mice) shows the LD50 value of 10.0 mg/kg[5].

Animal Model:S-180 bearing mice[4]
Dosage:0.5 mg/kg and 1 mg/kg
Administration:Intraperitoneal injection (i.p.) for 1-7 days
Result:Increased in median survival times.
Animal Model:HepG2 xenograft model [6]
Dosage:5 mg/kg
Administration:Intraperitoneal injection (i.p.), twice a day.
Result:Exhibited a relative tumor increment rates (T/C) value of 28.8%.

Mitonafide Preparation Products And Raw materials

Raw materials

Preparation Products

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Mitonafide Suppliers

Canada 1 China 25 Germany 1 India 1 United States 4 Global 32
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
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86-10-82849933
Email
jkinfo@jkchemical.com
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China
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Chemsky（shanghai）International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
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China
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32321
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50
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
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info@efebio.com
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China
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9803
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58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
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+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57422
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58
Nantong Hi-Future Biotechnology Co., Ltd
Tel
18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
2998
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58
TargetMol Chemicals Inc.
Tel
4008200310
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marketing@tsbiochem.com
Country
China
ProdList
24961
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58
https://hanhongsci.com/
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021-54306202 18917919676
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info@hanhongsci.com
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China
ProdList
29995
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58
Nanjing Shizhou Biology Technology Co.,Ltd
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025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
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China
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Shaoguan Qicheng Biotechnology Co., Ltd
Tel
18122215013
Email
780229652@qq.com
Country
China
ProdList
1292
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Sangon Biotech (Shanghai) Co.,Ltd.
Tel
400-821-026
Email
Sales@sangon.com
Country
China
ProdList
6710
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58
Biosynth Biological Technology (Suzhou) Co Ltd
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51288865780
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sales@biosynth.com
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China
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6051
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58
Selleck Chemicals
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400-668-6834
Email
info@selleck.cn
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China
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6071
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Santa Cruz Biotechnology Inc
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021-60936350
Email
scbt@scbt.com
Country
China
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6594
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58
Guangzhou CATO Research Chemicals Inc.
Tel
+86-020-81960175-617 +8615602392859
Email
Intermediate@cato-chem.com
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China
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3858
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Nantong HI-FUTURE Biology Co., Ltd.
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+undefined18051384581
Email
sales@chemhifuture.com
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China
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3135
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Absin Bioscience Inc.
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chenjw@absin.cn
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CHINA
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Proteintech China
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Proteintech-CN@ptglab.com
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Xiamen Research Biotechnology Co., Ltd.
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1562893815@qq.com
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CHINA
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Shanghai Ziqi Biological Technology Co., Ltd.
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2453006496@qq.com
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Shanghai Hao Biological Technology Co., Ltd.
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shxiyuanbio@163.com
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Beijing Fubo Biotechnology Co., Ltd.
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CHINA
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Xiamen Huijia Biological Technology Co., Ltd.
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CHINA
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6973
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Shanghai yiji industries Co., Ltd.
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--
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yiji01@foxmail.com
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China
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6021
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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info@zzsrm.com
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Lanospharma Laboratories Co.,Ltd
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6329
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54824-17-8, MitonafideRelated Search:

Mitoguazone 5-NITRO-1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONE Amonafide 1-METHYL-6-NITRONAPHTHALENE Mitonafide Pinafide 5-NITRO-2,3-DIHYDRO-1H-BENZO[DE]ISOQUINOLINE

  • 2-[2-(Dimethylamino)ethyl]-5-nitro-1H-benz[de]isoquinoline-1,3(2H)-dione
  • 2-[2-(Dimethylamino)ethyl]-5-nitro-1H-benzo[de]isoquinoline-1,3(2H)-dione
  • M-4212【pharmaceutical】
  • 1H-Benz[de]isoquinoline-1,3 (2H)-dione, 2-[2-(dimethylamino)ethyl]-5-nitro-
  • Aids070527
  • Aids-070527
  • N-(2-(Dimethylamino)ethyl)-3-nitronaphthalimide
  • Nsc300288
  • 3-Nitro-N-(2-dimethylaminoethyl)-1,8-naphthalimide
  • Mitonafide
  • Mitonafide, 10 mM in DMSO
  • 54824-17-8
  • Amines
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals