ChemicalBook > CAS DataBase List > Tiazofurine

Tiazofurine

Product Name
Tiazofurine
CAS No.
60084-10-8
Chemical Name
Tiazofurine
Synonyms
TCAR;CI 909;Aids014479;tiazofurin;Riboxamide;NSC-286193;Aids-014479;NSC-286-193;Tiazofurine;Tiazofurinum
CBNumber
CB31179908
Molecular Formula
C9H12N2O5S
Formula Weight
260.269
MOL File
60084-10-8.mol
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Tiazofurine Property

Melting point:
145-146°
alpha 
D25 -9° (c = 0.5 in ethanol)
Density 
1.4797 (rough estimate)
refractive index 
1.6800 (estimate)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)
form 
Solid
color 
White to Pale Beige
Stability:
Very Very Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological
Product number
295002
Product name
Tiazofurin
Packaging
2mg
Price
$486
Updated
2021/12/16
TRC
Product number
T437200
Product name
Tiazofurin
Packaging
25mg
Price
$795
Updated
2021/12/16
TRC
Product number
T437200
Product name
Tiazofurin
Packaging
50mg
Price
$1390
Updated
2021/12/16
AK Scientific
Product number
8957AB
Product name
2-b-D-Ribofuranosyl-4-thiazolecarboxamide
Packaging
25mg
Price
$1553
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0009152
Product name
TIAZOFURIN
Purity
95.00%
Packaging
5G
Price
$3817.8
Updated
2021/12/16
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Tiazofurine Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Tiazofurin has antitumor activity and is a potential therapeutic agent in the treatment of cancer. Tiazofurin acts as an inhibitor of Inosine-5''-monophosphate (IMP) dehydrogenase.

Definition

ChEBI: A C-glycosyl compound that is 1,3-thiazole-4-carboxamide in which the hydrogen at position 2 has been replaced by a beta-D-ribofuranosyl group. It is metabolised to thiazole-4-carboxamide adenine dinucle tide (TAD), a selective inhibitor of inosine monophosphate dehydrogenase (IMP dehydrogenase).

brand name

Tiazofurine is INN.

Tiazofurine Preparation Products And Raw materials

Raw materials

Preparation Products

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Tiazofurine Suppliers

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60084-10-8, TiazofurineRelated Search:

Hydroxyethyl Cellulose Nitrofurazone TIAZOFURINE, [3H]- 1-(2-PROPYL-1,3-THIAZOL-4-YL)METHANAMINE (4-METHYLTHIAZOL-2-YL)METHANOL Tiazofurine thiazole-4-carboxamide adenine dinucleotide

  • NSC-286193
  • NSC-286-193
  • Riboxamide
  • TCAR
  • 2-.beta.-D-Ribofuranosyl-4-thiazolecarboxamide
  • Tiazofurine
  • tiazofurin
  • Aids014479
  • Aids-014479
  • 2-β-D-Ribofuranosyl-4-thiazolecarboxaMide
  • 2-β-D-Ribofuranosylthiazole-4-carboxaMide
  • CI 909
  • 2-b-D-Ribofuranosyl-4-thiazolecarboxaMide
  • 4-Thiazolecarboxamide, 2-β-D-ribofuranosyl-
  • 2-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide
  • 2-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)thiazole-4-carboxamide
  • Nucleoside Antimetabolite/Analog,NSC-286193,Inhibitor,Tiazofurin,inhibit,NSC286193,Orthopoxvirus
  • Tiazofurinum
  • Tiazofurin, 10 mM in DMSO
  • 60084-10-8
  • Carbohydrates & Derivatives
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds