ChemicalBook > CAS DataBase List > Tiazofurine

Tiazofurine

Product Name
Tiazofurine
CAS No.
60084-10-8
Chemical Name
Tiazofurine
Synonyms
TCAR;CI 909;Aids014479;tiazofurin;Riboxamide;NSC-286193;Aids-014479;NSC-286-193;Tiazofurine;Tiazofurinum
CBNumber
CB31179908
Molecular Formula
C9H12N2O5S
Formula Weight
260.269
MOL File
60084-10-8.mol
More
Less

Tiazofurine Property

Melting point:
145-146°
alpha 
D25 -9° (c = 0.5 in ethanol)
Density 
1.4797 (rough estimate)
refractive index 
1.6800 (estimate)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)
form 
Solid
color 
White to Pale Beige
Stability:
Very Very Hygroscopic
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Usbiological
Product number
295002
Product name
Tiazofurin
Packaging
2mg
Price
$486
Updated
2021/12/16
TRC
Product number
T437200
Product name
Tiazofurin
Packaging
25mg
Price
$795
Updated
2021/12/16
TRC
Product number
T437200
Product name
Tiazofurin
Packaging
50mg
Price
$1390
Updated
2021/12/16
Biosynth Carbosynth
Product number
MT16870
Product name
Tiazofurin
Packaging
1mg
Price
$95
Updated
2021/12/16
Biosynth Carbosynth
Product number
MT16870
Product name
Tiazofurin
Packaging
2mg
Price
$150
Updated
2021/12/16
More
Less

Tiazofurine Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Tiazofurin has antitumor activity and is a potential therapeutic agent in the treatment of cancer. Tiazofurin acts as an inhibitor of Inosine-5''-monophosphate (IMP) dehydrogenase.

Definition

ChEBI: A C-glycosyl compound that is 1,3-thiazole-4-carboxamide in which the hydrogen at position 2 has been replaced by a beta-D-ribofuranosyl group. It is metabolised to thiazole-4-carboxamide adenine dinucle tide (TAD), a selective inhibitor of inosine monophosphate dehydrogenase (IMP dehydrogenase).

brand name

Tiazofurine is INN.

Tiazofurine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Tiazofurine Suppliers

Canada 1 China 34 India 1 United Kingdom 1 United States 3 Global 40

60084-10-8, TiazofurineRelated Search:

Hydroxyethyl Cellulose Nitrofurazone TIAZOFURINE, [3H]- 1-(2-PROPYL-1,3-THIAZOL-4-YL)METHANAMINE (4-METHYLTHIAZOL-2-YL)METHANOL Tiazofurine thiazole-4-carboxamide adenine dinucleotide

  • NSC-286193
  • NSC-286-193
  • Riboxamide
  • TCAR
  • 2-.beta.-D-Ribofuranosyl-4-thiazolecarboxamide
  • Tiazofurine
  • tiazofurin
  • Aids014479
  • Aids-014479
  • 2-β-D-Ribofuranosyl-4-thiazolecarboxaMide
  • 2-β-D-Ribofuranosylthiazole-4-carboxaMide
  • CI 909
  • 2-b-D-Ribofuranosyl-4-thiazolecarboxaMide
  • 4-Thiazolecarboxamide, 2-β-D-ribofuranosyl-
  • 2-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide
  • 2-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)thiazole-4-carboxamide
  • Nucleoside Antimetabolite/Analog,NSC-286193,Inhibitor,Tiazofurin,inhibit,NSC286193,Orthopoxvirus
  • Tiazofurinum
  • 60084-10-8
  • Carbohydrates & Derivatives
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds