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SHK

Product Name
SHK
CAS No.
172450-46-3
Chemical Name
SHK
Synonyms
SHK;SHNA;SHPK;CARKL;Sedoheptulokinase;STICHODACTYLA TOXIN;Carbohydrate kinase-like protein;Stichodactyla Toxin (0.1mg vial);STICHODACTYLA HELIANTHUS NEUROTOXIN;Recombinant Human SHPK Protein, His Tag
CBNumber
CB3119925
Molecular Formula
C169H274N54O48S7
Formula Weight
4054.77186
MOL File
172450-46-3.mol
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SHK Property

storage temp. 
-15°C
Sequence
Arg-Ser-Cys-Ile-Asp-Thr-Ile-Pro-Lys-Ser-Arg-Cys-Thr-Ala-Phe-Gln-Cys-Lys-His-Ser-Met-Lys-Tyr-Arg-Leu-Ser-Phe-Cys-Arg-Lys-Thr-Cys-Gly-Thr-Cys (Disulfide bridge: Cys3-Cys35; Cys12-Cys28; Cys17-Cys32)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Usbiological
Product number
S7973-56B
Product name
Stichodactyla Helianthus Neurotoxin
Packaging
1mg
Price
$531
Updated
2021/12/16
Biorbyt Ltd
Product number
orb372820
Product name
SHNA
Purity
> 95%
Packaging
1mg
Price
$552.5
Updated
2021/12/16
Biorbyt Ltd
Product number
orb530329
Product name
SHPK
Packaging
10μg
Price
$785.4
Updated
2021/12/16
Biorbyt Ltd
Product number
orb372820
Product name
SHNA
Purity
> 95%
Packaging
5mg
Price
$1174.7
Updated
2021/12/16
Biorbyt Ltd
Product number
orb372820
Product name
SHNA
Purity
> 95%
Packaging
10mg
Price
$1756.1
Updated
2021/12/16
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SHK Chemical Properties,Usage,Production

Uses

ShK toxin blocks voltage-dependent potassium channel (Kv1.3 channel). ShK toxin can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus). ShK toxin competes with dendrotoxin I and α-dendrotoxin for binding to synaptosomal membranes of rat brain, facilitates acetylcholine release. ShK toxin suppresses K+ currents in cultured rat dorsal root ganglion neurons. ShK toxin also inhibits T lymphocyte proliferation[1][2].

References

[1] Casta?eda O, et al. Characterization of a potassium channel toxin from the Caribbean Sea anemone Stichodactyla helianthus. Toxicon. 1995 May;33(5):603-13. DOI:10.1016/0041-0101(95)00013-c
[2] Beeton C, et al. The D-diastereomer of ShK toxin selectively blocks voltage-gated K+ channels and inhibits T lymphocyte proliferation. J Biol Chem. 2008 Jan 11;283(2):988-97. DOI:10.1074/jbc.M706008200

SHK Preparation Products And Raw materials

Raw materials

Preparation Products

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SHK Suppliers

China 43 Japan 2 Switzerland 1 United States 6 Global 52
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Cellmano Biotech Limited
Tel
0551-65326643 18156095617
Fax
0551-65326641
Email
info@cellmano.com
Country
China
ProdList
1010
Advantage
55
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 15951641583
Fax
025-58361106-806
Email
zhao.xu@njpeptide.com
Country
China
ProdList
9979
Advantage
55
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
7408
Advantage
58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19103
Advantage
58
Chengdu Peter-like Biotechnology Co., Ltd.
Tel
18108052721
Email
2850505130@qq.com
Country
China
ProdList
5167
Advantage
58
Cellmano Biotech Limited
Tel
0551-65326643 18156095617
Fax
0551-65326641
Email
info@cellmano.com
Country
China
ProdList
995
Advantage
58

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  • SHNA
  • SHK
  • STICHODACTYLA HELIANTHUS NEUROTOXIN
  • STICHODACTYLA HELIANTHUS NEUROTOXIN (SHK)
  • STICHODACTYLA HELIANTHUS NEUROTOXIN (SHNA)
  • STICHODACTYLA TOXIN
  • ARG-SER-CYS-ILE-ASP-THR-ILE-PRO-LYS-SER-ARG-CYS-THR-ALA-PHE-GLN-CYS-LYS-HIS-SER-MET-LYS-TYR-ARG-LEU-SER-PHE-CYS-ARG-LYS-THR-CYS-GLY-THR-CYS
  • H-ALA-ALA-CYS-LYS-CYS-ASP-ASP-GLU-GLY-PRO-ASP-ILE-ARG-THR-ALA-PRO-LEU-THR-GLY-THR-VAL-ASP-LEU-GLY-SER-CYS-ASN-ALA-GLY-TRP-GLU-LYS-CYS-ALA-SER-TYR-TYR-THR-ILE-ILE-ALA-ASP-CYS-CYS-ARG-LYS-LYS-LYS-OH
  • H-ARG-SER-CYS-ILE-ASP-THR-ILE-PRO-LYS-SER-ARG-CYS-THR-ALA-PHE-GLN-CYS-LYS-HIS-SER-MET-LYS-TYR-ARG-LEU-SER-PHE-CYS-ARG-LYS-THR-CYS-GLY-THR-CYS-OH
  • Anti-CARKL, N-Terminal antibody produced in rabbit
  • Carbohydrate kinase-like protein
  • CARKL
  • Sedoheptulokinase
  • SHPK
  • Recombinant Human SHPK Protein, His Tag
  • Toxin ShK(Stoichactis helianthus potassium-channel)
  • Stichodactyla Toxin (0.1mg vial)
  • 172450-46-3
  • C169H274N54O48S7