norisoboldine

Product Name: norisoboldine
CAS No.: 23599-69-1
Chemical Name: norisoboldine
Synonyms: quercitine;norisoboldine;Norisoboldine-RM;(+)-Laurelliptine;(+)-Norisoboldine;(+)-N-Norisoboldine;Modafinil Impurity 6;(S)-(+)-Laurelliptine;Norisoboldine, 98%, from Lindera aggregata (Sims) Kosterm.;(S)-2,10-Dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1,9-diol
CBNumber: CB31229250
Molecular Formula: C18H19NO4
Formula Weight: 313.35
MOL File: 23599-69-1.mol

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norisoboldine Property

Melting point:: 89-191℃
Boiling point:: 553.0±50.0 °C(Predicted)
Density: 1.313
solubility: ≥ 31.3mg/mL in DMSO
pka: 9.58±0.20(Predicted)
form: Powder
color: Brown to khaki
InChI: InChI=1S/C18H19NO4/c1-22-14-8-11-10(6-13(14)20)5-12-16-9(3-4-19-12)7-15(23-2)18(21)17(11)16/h6-8,12,19-21H,3-5H2,1-2H3/t12-/m0/s1
InChIKey: HORZNQYQXBFWNZ-LBPRGKRZSA-N
SMILES: N1[C@]2([H])C3=C(C(O)=C(OC)C=C3CC1)C1=CC(OC)=C(O)C=C1C2

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Safety

Safety Statements: 24/25
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL83266
Product name: Norisoboldine
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $549
Updated: 2025/07/31

TRC

Product number: N692025
Product name: (+)-Norisoboldine
Packaging: 5mg
Price: $275
Updated: 2021/12/16

Usbiological

Product number: 300689
Product name: Norisoboldine
Packaging: 20mg
Price: $390
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb259400
Product name: Norisoboldine
Purity: 98%
Packaging: 20mg
Price: $375.7
Updated: 2021/12/16

ApexBio Technology

Product number: N2400
Product name: Norisoboldine
Packaging: 20mg
Price: $400
Updated: 2021/12/16

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norisoboldine Chemical Properties,Usage,Production

Chemical Properties

Brown crystalline powder, soluble in methanol, derived from Linderae odorata.

Uses

(+)-Norisoboldine is an anti-arthritis alkaloid isolated from radix linderae which has been shown to attenuate osteoclast differentiation and inflammatory bone erosion in aryl hydrocarbon receptor-dependant manner.

in vivo

Norisoboldine (10~40 mg/kg; p.o.; 20 days) significantly reduces the severity of joint swelling and erythema during the course of the experiment^[1].
Norisoboldine (40 mg/kg; i.g.; 10 days) induces enhancement of CYP1A1 expression and suppresses expressions of Glut1 and HK2 in colons^[2].

Animal Model:	Male ICR mice (18–22 g)
Dosage:	10~40 mg/kg
Administration:	P.o.
Result:	Significantly reduced the severity of joint swelling and erythema during the course of the experiment.

Animal Model:	Female C57BL/6 mice (18–22 g)
Dosage:	40 mg/kg
Administration:	I.g.
Result:	Induced enhancement of CYP1A1 expression and suppressed expressions of Glut1 and HK2 in colons.

norisoboldine Preparation Products And Raw materials

Raw materials

Preparation Products

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norisoboldine Suppliers

China 165 Germany 1 United States 14 Global 180

Chengdu Nakeli Biotechnology Co., Ltd.

Tel: 028-61983833 19138982515
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Chembest Research Laboratories Limited

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Sichuan Kulinan Technology Co., Ltd

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Shenzhen Sungening Bio-Tech Co., Ltd

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Country: China
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Country: China
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ShangHai YuanYe Biotechnology Co., Ltd.

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Chengdu Biopurify Phytochemicals Ltd.

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Beijing HuaMeiHuLiBiological Chemical

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View Lastest Price from norisoboldine manufacturers

Career Henan Chemical Co

Product: norisoboldine 23599-69-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 25kg
Release date: 2019-07-12

23599-69-1, norisoboldineRelated Search:

LINDERANE Laetanine Boldine LAUROLITSINE HigenaMine Hydrochloride Linderene acetate (R,10E)-4,8,9,12-Tetrahydro-3,11-dimethyl-6H-4,7-methenofuro[3,2-c]oxacycloundecin-6-one Demethyl-Coclaurine Lindeneol norisoboldine BOLDINE DIMETHYL ETHER laurotetanine Thalicarpine L-DICENTRINE AKOS 208-03 4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)-

norisoboldine

(+)-Laurelliptine

(+)-N-Norisoboldine

(6aS)-5,6,6a,7-Tetrahydro-2,10-dimethoxy-4H-dibenzo[de,g]quinoline-1,9-diol

(S)-(+)-Laurelliptine

Norisoboldine, 98%, from Lindera aggregata (Sims) Kosterm.

4H-Dibenzo[de,g]quinoline-1,9-diol, 5,6,6a,7-tetrahydro-2,10-dimethoxy-, (6aS)-

(+)-Norisoboldine

(S)-2,10-Dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1,9-diol

quercitine

Norisoboldine-RM

Modafinil Impurity 6

23599-69-1

Cl8H19O4N

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract