ChemicalBook > CAS DataBase List > 7-Chlorothieno[3,2-b]pyridine
7-Chlorothieno[3,2-b]pyridine
- Product Name
- 7-Chlorothieno[3,2-b]pyridine
- CAS No.
- 69627-03-8
- Chemical Name
- 7-Chlorothieno[3,2-b]pyridine
- Synonyms
- 7-chlorothieno[3;7-Chlorothieno[3,2-b]pyri...;7-Chlorothieno[3,2-b]pyridine;Thieno[3,2-b]pyridine, 7-chloro-;7-Chlorothieno[3,2-b]pyridine 98%;7-Chlorothieno[3,2-B] pyridine, 98%min
- CBNumber
- CB31235200
- Molecular Formula
- C7H4ClNS
- Formula Weight
- 169.63
- MOL File
- 69627-03-8.mol
More
Less
7-Chlorothieno[3,2-b]pyridine Property
- Melting point:
- 34.0-35.5 °C
- Boiling point:
- 257.5±20.0 °C(Predicted)
- Density
- 1.435±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- powder to lump
- pka
- 2.87±0.30(Predicted)
- color
- White to Yellow to Orange
- InChI
- InChI=1S/C7H4ClNS/c8-5-1-3-9-6-2-4-10-7(5)6/h1-4H
- InChIKey
- GYQUXKQLCNFKQT-UHFFFAOYSA-N
- SMILES
- C12C=CSC1=C(Cl)C=CN=2
More
Less
Safety
- HS Code
- 2933399990
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
More
Less
N-Bromosuccinimide Price
TCI Chemical
- Product number
- C3541
- Product name
- 7-Chlorothieno[3,2-b]pyridine
- Packaging
- 1G
- Price
- $85
- Updated
- 2025/07/31
TCI Chemical
- Product number
- C3541
- Product name
- 7-Chlorothieno[3,2-b]pyridine
- Packaging
- 5G
- Price
- $300
- Updated
- 2025/07/31
TRC
- Product number
- C351375
- Product name
- 7-Chlorothieno[3,2-b]pyridine
- Packaging
- 5g
- Price
- $100
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FC53344
- Product name
- 7-Chlorothieno[3,2-B]Pyridine
- Packaging
- 5G
- Price
- $120
- Updated
- 2021/12/16
SynQuest Laboratories
- Product number
- 7H70-5-19
- Product name
- 7-Chlorothieno[3,2-b]pyridine
- Packaging
- 5G
- Price
- $150
- Updated
- 2021/12/16
More
Less
7-Chlorothieno[3,2-b]pyridine Chemical Properties,Usage,Production
Uses
7-Chlorothieno[3,2-b]pyridine is a pyridine derivative and a pharmaceutical intermediate compound. It can be used in the preparation of piperidines and deuterated thiophene pyridine compounds, and can also be used in the synthesis of compounds with anticancer activity.
Chemical Properties
7-Chlorothieno[3,2-b]pyridine is a white to yellow to orange powder to lumpy intermediate composition. It has a melting point of 35 °C and a flash point of 110 °C. It is stored at 0-10 °C. It is irritating to eyes and skin.
Synthesis
69627-02-7
69627-03-8
To a 250 mL round-bottomed flask were added 30 mL of methylene chloride and 20 mL of ethylene chloride, followed by N,N-dimethylformamide (1.8 mL, 23.28 mmol) and oxalyl chloride (2.9 mL, 33.86 mmol). Oxalyl chloride was slowly added dropwise to the mixture at 0 °C. Next, thieno[3,2-b]pyridin-7(4H)-one (1.6 g, 10.58 mmol) was added and the reaction mixture was heated to reflux for 6 hours. After completion of the reaction, the mixture was cooled to room temperature to afford 7-chlorothieno[3,2-b]pyridine (1.7 g, 90% yield) as a pale yellow solid. The product was characterized by 1H-NMR (400 MHz, CDCl3): δ 8.61 (d, J = 5.2 Hz, 1H), 7.81 (d, J = 5.2 Hz, 1H), 7.30 (d, J = 4.8 Hz, 1H).
References
[1] Patent: US2013/72482, 2013, A1. Location in patent: Paragraph 0281; 0286; 0287
[2] Patent: EP1724268, 2006, A1. Location in patent: Page/Page column 50-51
[3] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 1, p. 21 - 24
[4] Patent: CN107151240, 2017, A. Location in patent: Paragraph 0262; 0263; 0264
[5] Journal of Chemical Research, Miniprint, 1984, # 3, p. 771 - 795
7-Chlorothieno[3,2-b]pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
7-Chlorothieno[3,2-b]pyridine Suppliers
- Tel
- 021-34621078 13120882795
- Fax
- 021-34622517
- 465106944@qq.com
- Country
- China
- ProdList
- 857
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9310
- Advantage
- 66
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 86-0571-85151182
- Fax
- 86-0571-85151182
- Country
- China
- ProdList
- 5691
- Advantage
- 66
- Tel
- 021-64968085,64968086-5815,5812; 13472757003
- Fax
- +86 21 64968087
- xiaoxia.zeng@rainbowpharma.cn
- Country
- China
- ProdList
- 961
- Advantage
- 65
- Tel
- 0086-21-58956006
- Fax
- 0086-21-58956100
- Country
- China
- ProdList
- 7811
- Advantage
- 57
- Tel
- 021-54540637 18621091017
- Fax
- 021-34978309
- sales@amaspharm.com
- Country
- China
- ProdList
- 781
- Advantage
- 62
- Tel
- +86-25-68710855, +86-25-68710897
- Fax
- 025-68710856
- sales@springpharma.net
- Country
- China
- ProdList
- 1261
- Advantage
- 62
- Tel
- 021-56491756 13512199871
- Fax
- 021-5649-1756
- 2819742715@qq.com
- Country
- China
- ProdList
- 4000
- Advantage
- 55
- Tel
- 027-88041443 13072715837
- Fax
- 027-51829379
- sales@hetero-chem.com
- Country
- China
- ProdList
- 696
- Advantage
- 58
- Tel
- 15528092102
- Fax
- On Line QQ 2415375924
- Pharmsynth@hotmail.com
- Country
- China
- ProdList
- 116
- Advantage
- 60
- Tel
- 021-61551611 13296011611
- Fax
- ＋86 21-50676805
- contact@trustwe.com
- Country
- China
- ProdList
- 9895
- Advantage
- 58
- Tel
- 0531-81313138 13066006660
- Fax
- QQ: 3366077777
- chibapharm@foxmail.com
- Country
- China
- ProdList
- 3991
- Advantage
- 55
- Tel
- +86-21-60341587
- Fax
- +86-21-61294319
- sales@topbiochem.com
- Country
- China
- ProdList
- 6175
- Advantage
- 58
- Tel
- 18652989687
- Fax
- +86-25-52131256
- sales@norris-pharm.com
- Country
- China
- ProdList
- 8878
- Advantage
- 55
- Tel
- 150-2103-5486 18017383231
- Fax
- qq：2817624287
- 983544897@qq.com
- Country
- China
- ProdList
- 9342
- Advantage
- 55
- Tel
- +86-021-58975553
- Fax
- +86-021-58975554
- sales@cooperpharm.com
- Country
- China
- ProdList
- 1210
- Advantage
- 56
- Tel
- 021-60451683 15021268886
- Fax
- +86-21-60451682
- sales@arborchemical.com
- Country
- China
- ProdList
- 896
- Advantage
- 55
- Tel
- +86-18068513926
- Fax
- 0086-519-85153711
- Country
- China
- ProdList
- 1277
- Advantage
- 55
- Tel
- 027-027-87342388 18086026008
- Fax
- 027-87342388
- sales@kaymke.com
- Country
- China
- ProdList
- 3732
- Advantage
- 55
- Tel
- 021-62960152
- Fax
- 021-52212593
- 934678158@qq.com
- Country
- China
- ProdList
- 9899
- Advantage
- 55
- Tel
- 18939837085
- Fax
- 2880152141(QQ)
- youchemicals@gmail.com
- Country
- China
- ProdList
- 1839
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 0371-0371-13526885213 15637198702
- Fax
- 0371-63709726
- hsyykjchem@163.com
- Country
- China
- ProdList
- 3853
- Advantage
- 58
- Tel
- 18040571231/1402788087
- Fax
- sales@chemduro.com
- Country
- China
- ProdList
- 1973
- Advantage
- 58
- Tel
- 15281070185; 13038283958
- 2865097598@qq.com
- Country
- China
- ProdList
- 111
- Advantage
- 55
- Tel
- 021-61317773
- Fax
- 021-61486878
- sales@aspirebio.com
- Country
- China
- ProdList
- 2880
- Advantage
- 58
- Tel
- 18957373295
- Fax
- -
- Country
- China
- ProdList
- 1580
- Advantage
- 58
- Tel
- 0519-0519-83812535
- sales@qinuochem.com
- Country
- China
- ProdList
- 287
- Advantage
- 60
- Tel
- 0571-87396432
- Fax
- 0571-87396431
- sales@jhechem.com
- Country
- China
- ProdList
- 14912
- Advantage
- 59
- Tel
- 025-57018978 18251899859
- Fax
- 025-57018008
- sales@chalf-pharm.com
- Country
- China
- ProdList
- 5674
- Advantage
- 50
- Tel
- 0571-82896630 18969958410
- sales_hz@milestonepharmtech.com
- Country
- China
- ProdList
- 4894
- Advantage
- 55
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 716
- Advantage
- 55
- Tel
- Fax
- -
- eric_feng1954@126.com
- Country
- China
- ProdList
- 9248
- Advantage
- 55
- Tel
- 021-50908862，442785678，326799392 18721037013
- Fax
- 021-50908862
- siyansales@126.com
- Country
- China
- ProdList
- 9627
- Advantage
- 58
- Tel
- 526763801 13301653310
- Fax
- +86-21-51619052
- 526763801@qq.com
- Country
- China
- ProdList
- 9274
- Advantage
- 55
- Tel
- 0371-86658258
- Fax
- 0371-60996044
- info@coreychem.com
- Country
- China
- ProdList
- 10453
- Advantage
- 58
- Tel
- 021-58892003
- info@qiaochem.com
- Country
- China
- ProdList
- 6059
- Advantage
- 65
- Tel
- 0931-8235634 13321316780
- Fax
- +86(931) 4873122
- 1455540579@qq.com
- Country
- China
- ProdList
- 958
- Advantage
- 55
- Tel
- 00000000000
- Fax
- -
- sales@qingcangchem.com
- Country
- China
- ProdList
- 509
- Advantage
- 58
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 021-20242659 18930833303
- Fax
- +86 (21) 2024-2659
- Sales@changyanchem.cn
- Country
- China
- ProdList
- 5001
- Advantage
- 55
- Tel
- 028-83379370 13880556291
- Fax
- 028-87747383
- tcy@tcypharm.com
- Country
- China
- ProdList
- 7218
- Advantage
- 58
- Tel
- 0371-0371-55629727 13323845623
- Fax
- 037155629727
- 2885676761@qq.com
- Country
- China
- ProdList
- 10110
- Advantage
- 58
- Tel
- 18701958033
- Fax
- 021-60441077
- shzxchem@163.com
- Country
- China
- ProdList
- 649
- Advantage
- 58
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 18621295758
- Fax
- -QQ:1449085402
- 1449085402@qq.com
- Country
- China
- ProdList
- 1724
- Advantage
- 55
- Tel
- 025-66162170
- Fax
- 025-66162170
- Country
- China
- ProdList
- 7181
- Advantage
- 55
- Tel
- 17792809151
- Fax
- 18872220797
- 2355916837@ycphar.com
- Country
- China
- ProdList
- 6133
- Advantage
- 55
More
Less
View Lastest Price from 7-Chlorothieno[3,2-b]pyridine manufacturers
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
- Product
- 7-Chlorothieno[3,2-b]pyridine 69627-03-8
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-27
Career Henan Chemical Co
- Product
- 7-Chlorothieno[3,2-b]pyridine 69627-03-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%
- Supply Ability
- 500kg
- Release date
- 2018-08-19
69627-03-8, 7-Chlorothieno[3,2-b]pyridineRelated Search:
7-Chlorothieno[3,2-b]pyridine
7-CHLOROTHIENO[3,2-B]PYRIDINE-6-CARBONITRILE
7-CHLOROTHIENO[3,2-B]PYRIDINE-6-CARBOXYLIC ACID
7-CHLOROTHIENO[3,2-B]PYRIDINE-6-CARBOXAMIDE
5,7-DICHLORO-2-METHYLTHIENO[3,2-B]PYRIDINE
AKOS 93867
7-CHLORO-2-IODOTHIENO[3,2-B]PYRIDINE
7-CHLORO-2-IODOTHIENO[3,2-B]PYRIDINE-6-CARBONITRILE
5,7-DICHLORO-3-METHYLTHIENO[3,2-B]PYRIDINE
5,7-DICHLOROTHIENO[3,2-B]PYRIDINE
AKOS 93877